Unit PHYSIOLOGY

Course
Chemistry and technology of drugs
Study-unit Code
65013506
Location
PERUGIA
Curriculum
In all curricula
Teacher
Giovanna Traina
Teachers
  • Giovanna Traina
Hours
  • 48 ore - Giovanna Traina
CFU
6
Course Regulation
Coorte 2016
Offered
2017/18
Learning activities
Base
Area
Discipline biologiche
Academic discipline
BIO/09
Type of study-unit
Obbligatorio (Required)
Type of learning activities
Attività formativa monodisciplinare
Language of instruction
Italian
Contents
Physiology of neuron. Synapse. Physiology of muscle tissue. Spinal cord. Autonomic Nervous System.
Physiology of circulation. Physiology of respiration. Physiology of kidney. Physiology of digestive apparatus. Physiology of endocrine glands.
Reference texts
FISIOLOGIA, GL. Monticelli, CEA-ZANICHELLI
FISIOLOGIA, E.D'Angelo- A. Peres, Edi.Ermes
Educational objectives
The course has set itself the goal of illustrating the general operation of the main equipment, and stimulate the students' research of cellular and molecular mechanisms that underlie higher functions.
Prerequisites
In order to be able to understand and to know how to tackle the course, students must have the basic notions of human anatomy and biology, propedeutics to physiology.
Teaching methods
The course is organized as follows: Lectures on all subjects of the course.
Projection of movies concerning some topics that will complement the lectures.
Other information
Frequency: Compulsory, at least 70% of lessons
Learning verification modality
The exam consists of an oral test. Such oral test consists on an interview of about 20-30 minutes long aiming to ascertain the knowledge level and the understanding capability acquired by the student. The oral exam will also test the student communication skills and his autonomy in the organization and integration of the theoretical topics.
Extended program
Physiology of the neuron. Homeostasis. Transport phenomena across the plasma membrane. Ion channels. The neuron as a coaxial conductor. Diffusion potential.. Equilibrium potential. Resting potential. Action potential. The conduction of electrical signals along the excitable membranes. Conducting passive. Conduction of the action potential. Space constant. Time constant.
Physiology of synapses. Electrical synaptic transmission. Chemical synapse. Neural-muscular junction. Role of calcium. Presynaptic mechanisms of neurotransmitter release. Central chemical synapses. Chemical mediators. Synaptic integration. Criteria for defining a neurotransmitter. Synaptic receptors.
Physiology of skeletal muscle. Excitation-contraction coupling. Muscle contraction. Simple shock and tetanus muscle.
Smooth muscle.
The autonomic nervous system.
The Motor System. Physiology of reflexes.
Elementary models of learning.
Endocrine system. Steroid and peptide hormones. Hypothalamus. Releasing factors. Pituitary. Thyroid. Adrenal gland. Endocrine pancreas. Physiology of reproduction.
The cardiovascular system. The heart. Cardiac mechanics. Cardiac cycle. Heart's electrical activity. Action potential of nodal tissue and action potential of the contractile tissue. ECG. Cardiac output. Nervous and hormonal regulation. Circulation. Principles of hemodynamics. Blood pressure. Microcirculation. Blood pressure regulation. Venous return
The respiratory system. Respiratory mechanics. Respiratory volumes. Physical principles of gaseous exchange. Transport of oxygen and carbon dioxide in the blood. Regulation of respiration. Respiratory center. Chemical regulation of breathing.
The renal system. Kidney function. Renal processes. Glomerular filtration. Tubular reabsorption. Tubular secretion. GFR. Osmolarity and sodium concentration in the extracellular fluid. Countercurrent multiplication mechanism. Acid-base balance and its regulation.
The gastrointestinal system. Motility. Nervous control. Secretory functions of the digestive tract. Liver. Digestion and absorption.
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