Unit PHARMACOLOGY AND PHARMACOTHERAPY I

Course
Pharmacy
Study-unit Code
A000525
Location
PERUGIA
Curriculum
In all curricula
Teacher
Maria Teresa Pallotta
CFU
12
Course Regulation
Coorte 2020
Offered
2022/23
Type of study-unit
Obbligatorio (Required)
Type of learning activities
Attività formativa integrata

PHARMACOLOGY

Code A000526
Location PERUGIA
CFU 6
Teacher Maria Teresa Pallotta
Teachers
  • Maria Teresa Pallotta
Hours
  • 42 ore - Maria Teresa Pallotta
Learning activities Caratterizzante
Area Discipline biologiche e farmacologiche
Academic discipline BIO/14
Type of study-unit Obbligatorio (Required)
Language of instruction Italian
Contents Pharmacokinetics: disposition and metabolisms of drugs. Drug development, evaluation of new drugs and principles of therapeutics.
Reference texts R. Paoletti, S. Nicosia, F Clementi, G. Fumagalli
Farmacologia generale e molecolare, UTET, Torino
e
R. Paoletti, S. Nicosia, F Clementi, G. Fumagalli
Farmacologia clinica, UTET, Torino
Educational objectives The course of general pharmacology is the first of three teachings concerning Pharmacology. The main goal of education is to provide to the students the pharmacological basis for the understanding of the other two teachings, represented by Pharmacotherapy II Biological basis of biotechnologic drugs.. The general pharmacology is the study of the fundamentals of drug action that evaluates the relationship between body and drug, and analyzes the general mechanisms of interaction between the two systems. All the drugs share some general principles that are independent of the nature of the effect and which are common to all. The main knowledge gained will be related to: 1) absorption, distribution, metabolism and elimination of drugs 2) routes of administration of the drugs 3) bioavailability and bioequivalence 4) Receptors and theories of receptor activation 5) mechanisms of drug action and signal transduction pathways. The knowledge gained will enable the student to achieve the following skills: 1) be able to calculate the correct dosage of a drug 2) avoid toxic effects 3) rational use of medicines and achieve maximum efficacy with minimal toxicity
Prerequisites To effectively follow and understand the topics covered in the course of Pharmacognosy is necessary for the student to have a basic knowledge of Plant Biology.
The student who is going to the course Pharmacology, Pharmacognosy and Toxicology General must have successfully passed the exams of General and Applied Biochemistry and Molecular Biology that are very important for understanding the contents of the course of Pharmacology and the general objectives of learning. It would also be very useful that the student had successfully passed the exam in General physiology, which would allow him to easily understand the path of a drug in the body. The knowledge of these topics is indispensable for the student who wants to follow the course with profit.
Teaching methods Face-to-face teaching
Other information Compulsory course attendance
Learning verification modality witten exam
multple choise
Extended program General pharmacokinetics: passages of drugs across cell membranes; routes of administration and absorption; bioavailability; distribution of drugs in the body; volume of distribution, binding to plasma proteins; drug metabolism; excretion; time-course of drug plasmatic contents (after single or repeated administration).

PHARMACOTHERAPY I

Code 65007502
Location PERUGIA
CFU 6
Teacher Maria Teresa Pallotta
Teachers
  • Maria Teresa Pallotta
Hours
  • 42 ore - Maria Teresa Pallotta
Learning activities Caratterizzante
Area Discipline biologiche e farmacologiche
Academic discipline BIO/14
Type of study-unit Obbligatorio (Required)
Language of instruction Italian
Contents General principles of Pharmacology. Pharmacodynamics: drug receptors and receptors / mechanisms.
Reference texts R. Paoletti, S. Nicosia, F Clementi, G. Fumagalli
Farmacologia generale e molecolare, UTET, Torino
e
R. Paoletti, S. Nicosia, F Clementi, G. Fumagalli
Farmacologia clinica, UTET, Torino
Educational objectives The course of Pharmacotherapy I, is the first of three teachings concerning Pharmacology. The main goal of education is to provide to the students the pharmacological basis for the understanding of the other two teachings, represented by Pharmacotherapy II and Toxicology. The Pharmacotherapy I is the study of the fundamentals of drug action that evaluates the relationship between body and drug, and analyzes the general mechanisms of interaction between the two systems. All the drugs share some general principles that are independent of the nature of the effect and which are common to all. The main knowledge gained will be related to:
1) Receptors and theories of receptor activation
2) mechanisms of drug action and signal transduction pathways.
Prerequisites The student who is going to the course Pharmacotherapy I must have successfully passed the exams of General and Applied Biochemistry and Molecular Biology that are very important for understanding the contents of the course of Pharmacology and the general objectives of learning. It would also be very useful that the student had successfully passed the exam in General physiology, which would allow him to easily understand the path of a drug in the body. The knowledge of these topics is indispensable for the student who wants to follow the course with profit.
Teaching methods Face-to-face teaching
Other information Compulsory course attendance
Learning verification modality multiple choise exsam
Extended program General pharmacodynamics: targets and mechanisms of drug action; receptors, classification of mebrane receptors, intracellular receptors, dose-response curve; agonists, partial agonists, antagonists; individual variations (effects of age, pathological states, drug interactions, tolerance, placebo effects). General toxicity: side-effects, overdose, idiosyncratic and allergic reactions; teratogenesis and foetal toxicity; carcinogenesis; drug dependency
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