Unit GENERAL PHARMACOLOGY

Course
Biotechnology
Study-unit Code
55058306
Curriculum
In all curricula
Teacher
Maria Teresa Pallotta
Teachers
  • Maria Teresa Pallotta
Hours
  • 42 ore - Maria Teresa Pallotta
CFU
6
Course Regulation
Coorte 2020
Offered
2022/23
Learning activities
Affine/integrativa
Area
Attività formative affini o integrative
Academic discipline
BIO/14
Type of study-unit
Opzionale (Optional)
Type of learning activities
Attività formativa monodisciplinare
Language of instruction
Italian
Contents
Pharmacokinetics: the dynamic of drug absortion, distribution, metabolism and elimination. Routes of administration
Pharmacodynamics
- Molecular drug targets
- Families of receptors and signaling pathways
- Quantitation of drug-receptor interaction and effects, radioligand binding method, molecular characterization (ion channels, G-protein-coupled receptor, receptor protein kinases, intracellular receptors).
- Transcription factors.
- Agonist and antagonist ligands
- Regulation of receptors
- Pharmacogenomics and pharmacogenetics
- Pharmacology of biotechnologic drugs
Reference texts
Paoletti, Nicosia, Clementi, Fumagalli "Farmacologia generale e molecolare" UTET
Educational objectives
Biotechnologic competence - Knowledge and comprehension of the production, analysis and control of drugs obtained by means of
biotechnologic processes; general principles of pharmacology in relationship to the project of drugs and in general of bioactive molecules
obtained by means of biotechnologic processes; structura and biologic properties of animal and plant cells and tissues.
Prerequisites
Having passed the exams of Physiology and Biochemistry
Teaching methods
Face-to-face theoretical lessons
Other information
Private Facebook group
Learning verification modality
Written exam with open answers
Extended program
Introduction to pharmacology.
Concept of drug and medication.
Chemical and physical properties of drugs.
Pharmacokinetics: the dynamic of drug absortion, distribution, metabolism and elimination. Routes of administration
Pharmacodynamics
- Molecular drug targets
- Families of receptors and signaling pathways
- Quantitation of drug-receptor interaction and effects, radioligand binding method, molecular characterization (ion channels, G-protein-coupled receptor, receptor protein kinases, intracellular receptors).
- Transcription factors.
- Agonist and antagonist ligands
- Regulation of receptors
- Pharmacogenomics and pharmacogenetics
- Pharmacology of biotechnologic drugs
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