Unit PHYSICAL CHEMISTRY
- Course
- Biotechnology
- Study-unit Code
- 55009006
- Curriculum
- In all curricula
- CFU
- 6
- Course Regulation
- Coorte 2021
- Offered
- 2022/23
- Learning activities
- Caratterizzante
- Area
- Discipline biotecnologiche con finalità specifiche:chimiche e farmaceutiche
- Academic discipline
- CHIM/02
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa monodisciplinare
PHYSICAL CHEMISTRY - Canale A
| Code | 55009006 |
|---|---|
| CFU | 6 |
| Teacher | Fausto Elisei |
| Teachers |
|
| Hours |
|
| Learning activities | Caratterizzante |
| Area | Discipline biotecnologiche con finalità specifiche:chimiche e farmaceutiche |
| Academic discipline | CHIM/02 |
| Type of study-unit | Obbligatorio (Required) |
PHYSICAL CHEMISTRY - Canale B
| Code | 55009006 |
|---|---|
| CFU | 6 |
| Teacher | Loredana Latterini |
| Teachers |
|
| Hours |
|
| Learning activities | Caratterizzante |
| Area | Discipline biotecnologiche con finalità specifiche:chimiche e farmaceutiche |
| Academic discipline | CHIM/02 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian |
| Contents | Light-matter interaction. UV-Vis spectroscopy (absorption and emission). Circular dichroism. Applications to moleculari systems of biological interest. Kinetic laws. Reaction mechanisms. Reaction rate and temperature. Catalysis. |
| Reference texts | P. W. Atkins and J. de Paula, Physical Chemistry, Oxford University Press |
| Educational objectives | It is expected that at the end of the course the students have acquired basic knowledge of classical thermodynamics and chemical kinetics, are able to perform simple numerical exercises and are able to apply their knowledge to subsequent courses of study. It is also expected that the content of the teaching will contribute to the development of the following biotechnology skills: Knowledge and understanding of organic chemistry and biochemistry aimed at understanding the structural and functional properties of biological macromolecules, metabolism of nutrients and metabolic integrations, regulation mechanisms operating in biological systems and methodologies of molecular level analysis. |
| Prerequisites | In order to be able to understand the topics covered in the course, students must have basic knowledge of General and Inorganic Chemistry as regards the concepts of chemical bonding, chemical reaction, chemical equilibrium and Mathematical Analysis regarding the use of derivatives and integrals. The latter concepts will still be treated in some alignment lessons of the course of Physical Chemistry. |
| Teaching methods | Lectures with slide shows. Some lessons will be dedicated to revision and deepening of the issues addressed, some others to carry out numerical applications. |
| Other information | Attendance is not compulsory but strongly recommended. |
| Learning verification modality | They consist of an oral test dealing with concepts and their application in numerical exercises. This test will serve to verify the communication skills of the student, his/her properties of language and autonomous organization of the exposure on the topics covered in class. For information on support services for students with disabilities and / or DSA visit the page http://www.unipg.it/disabilita-e-dsa |
| Extended program | 1) SPECTROSCOPY: Optical spectroscopy as a tool for structural, conformational and energetic investigation of molecules of biological relevance. Elements of quantum mechanics. The electromagnetic radiation. Light-matter interaction. Absorption and diffusional processes of the electromagnetic radiation. UV-Vis spectroscopy; aromatic amino acids and proteins. Linear and circular dichroism. Lambert-Beer law. Analytical CD methods to determine the secondary structure of proteins. Emission processes of the electromagnetic radiation (fluorescence and phosphorescence); emission spectra, quantum yields and lifetimes. Processes of electronic energy transfer, FRET. 2) CHEMICAL KINETICS Chemical reaction rate. Order and molecularity. Rate laws. Reaction mechanisms. Steady-state approximation. Dependence of the reaction rate by the temperature. Experimental techniques. Collisions and transition state theories. Chemical reaction molecularity. reactions in homogenous and heterogenous media. Catalysis and inhibition. |