Unit BIOCHEMISTRY

Course
Biotechnology
Study-unit Code
55042606
Curriculum
In all curricula
CFU
6
Course Regulation
Coorte 2021
Offered
2022/23
Learning activities
Caratterizzante
Area
Discipline biotecnologiche comuni
Academic discipline
BIO/10
Type of study-unit
Obbligatorio (Required)
Type of learning activities
Attività formativa monodisciplinare

BIOCHEMISTRY - Canale A

Code 55042606
CFU 6
Teacher Carla Emiliani
Teachers
  • Lorena Urbanelli (Codocenza)
  • Carla Emiliani
Hours
  • 20 ore (Codocenza) - Lorena Urbanelli
  • 22 ore - Carla Emiliani
Learning activities Caratterizzante
Area Discipline biotecnologiche comuni
Academic discipline BIO/10
Type of study-unit Obbligatorio (Required)
Language of instruction Italian
Contents Aminoacids. Structure and function of proteins. Hemoglobin and myoglobin. Enzymes: enzyme catalysis and kinetics, mechanisms of enzyme control. Molecular constituents and supramolecular architecture of biological membranes. Introduction to the principles of metabolism and bioenergetics. Glycolysis and beta-oxidation of fatty acids. Tricarboxylic acid cycle. Chain electron transport and oxidative phosphorylation. Gluconeogenesis and fatty acid biosynthesis. Practical training: Determination of the protein concentration of a biological sample. Virtual Lab: Provides the student's active participation through a virtual path that will guide him in the design and implementation of an experiment about cellular respiration.
Reference texts D. Voet, J.G. Voet, Fondamenti di Biochimica, Ed. Zanichelli
Nelson, M.M.Cox, Introduzione alla biochimica di Lehninger, Ed. Zanichelli
Nelson, M.M.Cox, Principi di Biochimica di Lehninger, Ed. Zanichelli
Educational objectives Knowledge: at the end of the course the student will have to know the composition, structural and functional organization of bio-molecules and macromolecules (proteins, lipids, sugars) and their interaction methods. He will also need to know the main metabolic pathways and the molecular mechanisms of the cell's intermediate and energy metabolism.

Capacity: at the end of the course the student must be able to relate the knowledge acquired in the abiotic field, in the General Chemistry and Organic Chemistry courses, to a Chemical-Biological field. He must be able to integrate the acquired knowledge into a coherent framework.
Prerequisites In order to be able to understand and profitably attend the Course, it is useful that the student possesses a working knowledge of general and inorganic chemistry, organic chemistry and cell biology.
Teaching methods Lectures on all subjects of the course. Lessons will be integrated with slide projections and movies.
Other information Tutoring activities during the course and the practical training will be performed.

For the timetable of lessons please consult the website of the course: http://biotecnologie.unipg.it
Learning verification modality They consist of a written examination followed by an oral examination. In the written test via the omline platform LiBRE-EOL (Lasting up to 40 min) students have to answer to thirty multiple-choice questions. This text will be used to verify the level of knowledge acquired.
The oral exam is only for students who pass the written exam with a score equal to or greater than 18/30. This test will allow to resolve gaps emerged on written test and to check their communication ability, proper scientific language and autonomous capability of the presentation of topics of the course. The final score will consider both written and oral exams.
Students, who have not passed the written test, will have the possibility to discuss about their problems with the teacher, the day of the oral examination.
Extended program Aminoacids. Structure and function of proteins. Hemoglobin and myoglobin. Enzymes: enzyme catalysis and kinetic; mechanisms of inhibition and regulation of enzyme activity. Molecular constituents and supramolecular architecture of biological membranes. Introduction to metabolism. Principles of bioenergetics and biological redox reactions. ATP. Glycolysis. Beta-oxidation of fatty acids. Tricarboxylic acid cycle. Chain electron transport and oxidative phosphorylation. Gluconeogenesis and Biosynthesis of fatty acids . Outline of the metabolism of amino acids: glucogenic and ketogenic amino acids. Deamination of amino acids.

BIOCHEMISTRY - Canale B

Code 55042606
CFU 6
Teacher Brunella Tancini
Teachers
  • Brunella Tancini
Hours
  • 42 ore - Brunella Tancini
Learning activities Caratterizzante
Area Discipline biotecnologiche comuni
Academic discipline BIO/10
Type of study-unit Obbligatorio (Required)
Language of instruction Italian
Contents Aminoacids. Structure and function of proteins. Hemoglobin and myoglobin. Enzymes: enzyme catalysis and kinetics, mechanisms of enzyme control. Molecular constituents and supramolecular architecture of biological membranes. Introduction to the principles of metabolism and bioenergetics. Glycolysis and beta-oxidation of fatty acids. Tricarboxylic acid cycle. Chain electron transport and oxidative phosphorylation. Gluconeogenesis.
Reference texts - D. Voet, J.G. Voet, Fondamenti di Biochimica, Ed. Zanichelli
- Nelson, M.M.Cox, Introduzione alla biochimica di Lehninger, Ed. Zanichelli
- Nelson, M.M.Cox, Principi di Biochimica di Lehninger, Ed. Zanichelli
Educational objectives The main purpose of the course is to provide students with a solid knowledge and understanding of biochemistry aimed at understanding the structural and functional properties of biological macromolecules, nutrient metabolism and regulatory mechanisms in biological systems. Main knowledge acquired will be the composition, structural and functional organization of bio-molecules and -macromolecule (proteins, lipids, sugars) and their interaction mechanisms. Students will also gain knowledge of the main metabolic pathways and molecular mechanisms of the intermediary and energetic cell metabolism.
Prerequisites In order to be able to understand and profitably attend the Course, it is useful that the student possesses a working knowledge of general and inorganic chemistry, organic chemistry and cell biology
Teaching methods The course is organized in
Lectures on all subjects of the course. Lessons will be integrated with slide projections and movies.
Other information Tutoring activities during the course and the practical training will be performed.

For the timetable of lessons please consult the website of the course: http://biotecnologie.unipg.it
Learning verification modality It consists of an oral test based on three main questions related to the topics covered during the course: one question will be on structural biochemistry, one on metabolism and the third will depend on the general outcome of the exam. This test will aim to verify the student's communication skills with linguistic properties and autonomous organization of the exposure of the topics covered in class; the ability to reason and connect the various topics will also be assessed.
Extended program Theoretical lessons: Aminoacids. Structure and function of proteins. Hemoglobin and myoglobin. Enzymes: enzyme catalysis and kinetic; mechanisms of inhibition and regulation of enzyme activity. Molecular constituents and supramolecular architecture of biological membranes. Introduction to metabolism. Principles of bioenergetics and biological redox reactions. ATP. Glycolysis. Beta-oxidation of fatty acids. Tricarboxylic acid cycle. Chain electron transport and oxidative phosphorylation. Gluconeogenesis. Outline of the metabolism of amino acids: glucogenic and ketogenic amino acids. Deamination of amino acids.
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