Unit MOLECULAR AND BIOLOGICAL BASES

BIOCHEMISTRY

Code	GP003698
CFU	2
Teacher	Ilaria Bellezza
Teachers	Ilaria Bellezza
Hours	24 ore - Ilaria Bellezza
Learning activities	Base
Area	Scienze biomediche
Sector	BIOS-07/A
Type of study-unit	Obbligatorio (Required)

APPLIED BIOLOGY

Code	GP003700
CFU	1
Teacher	Cinzia Antognelli
Teachers	Cinzia Antognelli
Hours	12 ore - Cinzia Antognelli
Learning activities	Base
Area	Scienze biomediche
Sector	BIOS-10/A
Type of study-unit	Obbligatorio (Required)
Language of instruction	Italian
Contents	Cell Biology,main functions: Protein synthesis, Gene expression, cellular communication.
Reference texts	"Biochimica e biologia per le professioni sanitarie" di Roberti, Alunni Bistocchi, Antognelli e Talesa (McGraw-Hill) Biologia & genetica Donati - Stefani - Taddei Zanichelli
Educational objectives	The course in Applied Biology provides students with fundamental knowledge of the organization of living matter, as well as the structure and function of the cell and the main biological and molecular mechanisms that regulate cellular processes. Particular attention is given to the mechanisms of transmission and expression of genetic information, cellular proliferation and differentiation processes, and the basic principles of biological homeostasis. This course constitutes a foundational prerequisite for the understanding of subsequent courses in Histology, Biochemistry, Physiology, and the core professional disciplines.
Prerequisites	The achievement of the learning outcomes requires a basic knowledge of General Chemistry, with particular reference to the fundamental principles of the structure of matter and chemical interactions.
Teaching methods	Face-to-face lectures.
Other information	Instructor’s Office Location: Department of Medicine and Surgery – Building B, 4th floor – P.le L. Severi 1 – Sant’Andrea delle Fratte – Perugia, Italy. Student Office Hours: The instructor is available to meet students upon request. Appointments can be arranged by email at: cinzia.antognelli@unipg.it
Learning verification modality	Multiple-choice test consisting of 30 questions, each with 5 answer options, of which only one is correct. Each correct answer is awarded 1 point. There are no penalties for incorrect or unanswered questions. The time allowed for completing the test is 30 minutes. For information on support services for students with disabilities and/or Specific Learning Disorders (SLD), please visit: http://www.unipg.it/disabilita-e-dsa
Extended program	Characteristics of living organisms. Biological macromolecules: proteins, lipids, and carbohydrates (general overview). Organization of the eukaryotic cell. Bacteria and viruses: general overview. Animal eukaryotic cell. Plasma membrane: structure and functions, with particular reference to mechanisms of transport and cell communication; cytoplasm; ribosomes; smooth and rough endoplasmic reticulum; Golgi apparatus; lysosomes; peroxisomes; mitochondria and the energy problem; cytoskeleton (general overview); nucleus and nucleolus. DNA and RNA: structure and function. Chromatin organization and chromosomes. Human karyotype. Gene expression (general overview). Cell cycle and its regulation. Reproduction in multicellular organisms; meiosis and its significance; male and female gametogenesis.
Obiettivi Agenda 2030 per lo sviluppo sostenibile	3. Health and wellness

FUNCTIONAL HISTOLOGY

Code	GP003699
CFU	2
Teacher	Lorella Marinucci
Teachers	Lorella Marinucci
Hours	24 ore - Lorella Marinucci
Learning activities	Base
Area	Scienze biomediche
Sector	BIOS-13/A
Type of study-unit	Obbligatorio (Required)
Language of instruction	Italian
Contents	Epithelia. Exocrine and endocrine glands. Connective tissues tissue. Aponeurosis, tendons and ligaments. Adipose tissue. Types of cartilage. Bone tissue. Bone formation. Blood. Smooth, skeletal and cardiac muscle tissues. Nervous tissue.
Reference texts	G. Istologia per le professioni sanitarie G.Sica et al. Ed. Idelson Gnocchi
Educational objectives	Knowledge and understanding of the structure and ultrastructure of cells, tissues and organs and correlation between structure and function to understand the phisio-pathogenetic processes.
Prerequisites	In order to be able to understand and apply the majority of the contents described within the course, the student must have acquired basic knowledge of cellular biology and chemistry.
Teaching methods	Face to face with slide projections.
Other information	The attendance is compulsoryRoom first year of Fisiotherapy , via Oberdan 123 Foligno
Learning verification modality	The exam includes an oral exam of Histology (almost three questions. about 20 minutes) to assess logical and knowledge competence learning and the ability to interpret data. The oral exam will verify that the student is able to communicate, with method, propriety of language and of exposure. A further question on the minimum essential knowledge may be asked in the event of an unsatisfactory answer to the 3 previous questions. The final grade will be the arithmetic weighted average of the grades obtained in the individual disciplines.
Extended program	Stem cells. Epithelia. Exocrine and endocrine glands. Connective tissue. Extracellular matrix. The cells of the connective tissue. Aponeurosis, tendons and ligaments. Adipose tissue. Types of cartilage. Bone tissue. Intramembranous bone formation. Endochondral bone formation. Blood. Smooth, skeletal and cardiac muscle tissues. Nervous tissue. Nerve fibers, peripheral nerves. Interneuronic synapses. Neuromuscular synapse.
Obiettivi Agenda 2030 per lo sviluppo sostenibile	Zero poverty Health and wellness Decent work and economic growth