Unit PHARMACEUTICAL AND HEALTH PRODUCT ANALYSIS
- Course
- Quality control of healthcare products
- Study-unit Code
- A005292
- Curriculum
- In all curricula
- Teacher
- Serena Massari
- Teachers
-
- Serena Massari
- Hours
- 73 ore - Serena Massari
- CFU
- 7
- Course Regulation
- Coorte 2025
- Offered
- 2026/27
- Learning activities
- Caratterizzante
- Area
- Discipline farmaceutiche e tecnologiche
- Sector
- CHIM/08
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa monodisciplinare
- Language of instruction
- Italian
- Contents
- Understanding the chemical and pharmacotoxicological aspects of the primary inorganic and organic compounds listed in the most recent edition of the Official Pharmacopoeia. Knowledge of the theoretical principles of quantitative volumetric analysis using acid-base, complexometric, and redox titrations. There are individual practical laboratory exercises focused on the qualitative and quantitative analysis of the studied compounds.
- Reference texts
- : i) PDF delle lezioni e dei procedimenti di analisi (UNISTUDIUM); ii) A. Carta, M. G. Mamolo, F. Novelli, S. Piras - Analisi Farmaceutica Qualitativa - Editrice EDISES; ii) A. Carrieri - Manuale di Analisi Quantitativa dei Medicinali - Editrice EDISES; iii) A. Crea. Principi di chimica analitica (Ed. Zanichelli); iv) V. Cavrini, V. Andrisano - Principi di analisi farmaceutica - Società Editrice Esculapio.
- Educational objectives
- This course provides the fundamental theoretical and practical knowledge necessary for working safely in a chemical-analytical laboratory and critically consulting the current Official Pharmacopoeia. Students will learn about the chemical and pharmacotoxicological aspects of inorganic, organometallic, and organic compounds of pharmaceutical interest. They will also learn about the chemical and physical principles of quantitative volumetric analysis. By the end of the course, students will have developed the manual dexterity and logical rigor necessary to independently apply qualitative and quantitative analytical methodologies. They will be able to identify unknown substances or formulations and perform acid-base, precipitation, and redox volumetric determinations. Students will also be able to critically evaluate experimental data, use appropriate scientific terminology, and write clear, comprehensive technical reports on their work.
- Prerequisites
- Students enrolling in this course must have a solid foundation in general, inorganic, and organic chemistry. These subjects are essential prerequisites for successfully completing the course. According to the Academic Regulations, students must pass the exams in General and Inorganic Chemistry and Organic and Bio-organic Chemistry to enroll in this course.
- Teaching methods
- The course consists of theoretical lectures and practical laboratory exercises. Lectures are delivered both synchronously and asynchronously online and in person. Course materials are made available in advance on the UNISTUDIUM platform to support lectures. Laboratory activities are conducted entirely in person. They consist of individual practical exercises aligned with the lectures and focused on performing qualitative and quantitative analyses. A summary introduction to the work to be carried out precedes each practical session, and the session features constant direct interaction between the instructor and students for clarifications and critical discussion.
- Other information
- As required by the Academic Regulations, attendance is mandatory for at least 70% of class hours.
- Learning verification modality
- Learning is assessed through ongoing laboratory tests focused on identifying unknown compounds. The final exam is an oral exam centered on discussing the theoretical and practical topics covered in the syllabus. This evaluation measures students’ knowledge of the qualitative and quantitative aspects of the studied compounds, their ability to identify inorganic, organometallic, and organic substances, and their ability to correctly perform volumetric determinations. Students will also be evaluated on their knowledge of the current Official Pharmacopoeia, ability to critically analyze experimental data, presentation skills, and proficiency in scientific language. The oral exam averages 30 minutes. For information on support services for students with disabilities and/or learning disabilities, visit http://www.unipg.it/disabilita-e-dsa.
- Extended program
- Safety Regulations and Management of Laboratory Materials: Analytical procedures for the qualitative inorganic analysis of anions, cations, and salt mixtures of pharmaceutical interest, as described in the current official pharmacopoeia. The study of the chemical and physical properties of drugs, solubility classes, behavior during calcination, and the experimental determination of physical constants, such as melting point and specific optical rotation. Qualitative organic elemental analysis using the Lassaigne and Beilstein methods. Reactive characterization of the main functional groups, aromatic structure, and degree of unsaturation. Analytical profile, identification reactions, sorting schemes, and specific chemical assays for classes of organic, organometallic, and derivative drugs listed in the Pharmacopoeia, with particular reference to carbohydrates, sulfonamides, and organic acids. Application and interpretation of thin-layer chromatography. Study of the theoretical principles of volumetric quantitative analysis, including preparation of standard solutions, use of stock solutions, expression of concentration, titration curves, criteria for selecting indicators, and analytical error. An in-depth study of acid-base volumetric titrations in aqueous and nonaqueous media, complexometric titrations, and redox titrations is also included. The hands-on laboratory exercises focus on applying Pharmacopoeia tests, qualitatively identifying unknown substances (whether isolated or in mixtures), and quantitatively determining the concentration of active ingredients using volumetric methods.
- Obiettivi Agenda 2030 per lo sviluppo sostenibile
- Salute e benessere
Istruzione di qualità