| Code |
A001762 |
| CFU |
6 |
| Teacher |
Claudio Costantini |
| Teachers |
|
| Hours |
- 42 ore - Claudio Costantini
|
| Learning activities |
Caratterizzante |
| Area |
Discipline biotecnologiche comuni |
| Sector |
MEDS-02/A |
| Type of study-unit |
Obbligatorio (Required) |
| Language of instruction |
English |
| Contents |
Biotechnologies that use immunological tools in the study, diagnosis and therapy of human pathology, with a selection of the most advanced immunological, cellular and molecular tools. |
| Reference texts |
Janeway's Immunobiology Garland Science Abbas, Lichtman, Pillai: Cellular and Molecular Immunology |
| Educational objectives |
Knowledge of the immune system and the main immunological approaches in the biotechnology sector. |
| Prerequisites |
Cell biology and signal transduction. Cells of the innate and specific immune system. Basic mechanisms of the immune response. |
| Teaching methods |
Frontal lessons, inverted classes. |
| Learning verification modality |
Classroom discussion. Oral exam on basic immunology and biotechnological applications |
| Extended program |
- Microbiota: definitions, general characteristics, gastrointestinal microbiota, respiratory microbiota, oral microbiota, the microbiome biotech landscape - Innate Immune System: macrophages and macrophage-based therapies, dendritic cells and dendritic cell-based therapies, innate immune receptors and receptor-ligand engineering, cytokines and cytokine therapeutics, NK cells and NK cell-based therapies. Adaptive Immune System: lymphoid organs and organ-on-a-chip technology, T cells and CAR-T cells, B cells and antibodies, monoclonal antibodies and antibody humanization, antibody-drug conjugate, bispecific antibodies, Fc-fusion proteins, nanobodies. |
