Unit BIOMOLECULES APPLIED TO THE STUDY OF BIOLOGICAL SYSTEMS
- Course
- Industrial pharmacy
- Study-unit Code
- A003604
- Curriculum
- In all curricula
- Teacher
- Carmela Conte
- Teachers
-
- Carmela Conte
- Hours
- 32 ore - Carmela Conte
- CFU
- 4
- Course Regulation
- Coorte 2023
- Offered
- 2023/24
- Learning activities
- Affine/integrativa
- Area
- Attività formative affini o integrative
- Academic discipline
- BIO/10
- Type of study-unit
- Opzionale (Optional)
- Type of learning activities
- Attività formativa monodisciplinare
- Language of instruction
- Italian
- Contents
- Biomolecules and methods of study of their structural and functional properties. Interactions between macromolecules. Production of compounds with therapeutic potential.
- Reference texts
- BIOINFORMATICA, S. Pascarella-A.Paiardini, Zanichelli Editore; I PRINCIPI DI BIOCHIMICA DI LEHNINGER, D.L. Nelson, M.M. Cox, Zanichelli Editore; BIOLOGIA MOLECOLARE DELLA CELLULA, Bruce Alberts Alexander Johnson Julian Lewis David Morgan Martin Raff Keith Roberts Peter Walter, Zanichelli Editore; FONDAMENTI DI BIOINFORMATICA, Helmer Citterich, Ferrè, Pavesi, Pesole, Romualdi, Zanichelli Editore. Handouts provided by the teacher
- Educational objectives
- At the end of the study the student will be able to acquire the basic knowledge of the principles underlying the use of biomolecules and related to their structural and functional characterization. Furthermore, they will have acquired new knowledge relating to the diagnostic and therapeutic applications of some macromolecules.
- Prerequisites
- The course aims to address topics that the student will be able to follow if he has acquired the basic knowledge of general and molecular biochemistry. In order to understand the contents covered, it is essential that the student has acquired the fundamental notions on the structure and function of the main biological macromolecules and the fundamental mechanisms underlying the cellular regulatory processes.
- Teaching methods
- The course is organized as follows: Lectures in the classroom covering all the topics of the program.
- Learning verification modality
- The test will include an oral exam during which the student will have to answer questions concerning topics covered during the frontal lessons and listed in the programme. During the oral test, the student will have to demonstrate consistency with the proposed question, clarity of presentation and correctness of scientific terminology.
- Extended program
- - Biomolecules: Structure and function
- The omic sciences
- Protein folding.
- Concepts of proteomics
Databases as tools for similarity search or sequence alignment.
- Study of the interaction between macromolecules and investigation methods.
- Regulation of gene expression: antisense oligonucleotides, siRNA, anti-miRNA.
- Nanoparticles and interaction with biological systems.
- Lipid therapy membranes for the treatment of pathologies, such as neurodegenerative diseases. - Obiettivi Agenda 2030 per lo sviluppo sostenibile
- Health and wellness.