Unit INNOVATIVE THERAPIES IN PHARMACOLOGY

Course
Industrial pharmacy
Study-unit Code
A003607
Curriculum
In all curricula
Teacher
Marco Gargaro
Teachers
  • Marco Gargaro
Hours
  • 32 ore - Marco Gargaro
CFU
4
Course Regulation
Coorte 2023
Offered
2023/24
Learning activities
Affine/integrativa
Area
Attività formative affini o integrative
Academic discipline
BIO/14
Type of study-unit
Opzionale (Optional)
Type of learning activities
Attività formativa monodisciplinare
Language of instruction
Italian
Contents
This course will provide students with a general overview of innovative immunology-based therapies currently under development for the treatment of rare diseases, oncological conditions, inflammatory disorders, and autoimmune diseases. In particular, the basic concepts of immunology necessary for understanding advanced next-generation cellular therapies will be provided.
Reference texts
Immunobiologia di Janeway, a cura di Kenneth Murphy, Casey Weaver, Massimo Locati, Piccin-Nuova Libraria, 2019.
Educational objectives
The main objective of this course is to provide students with the basic concepts for identifying and validating new immunological targets for the development of advanced and personalized pharmacological strategies.
Prerequisites
Successful completion of exams in General Pharmacology, Pharmacotherapy, and Experimental Pharmacology is required. Knowledge of these subjects is essential for students who wish to successfully pursue the course.
Teaching methods
Theoretical lessons
Other information
Recommended frequency
Learning verification modality
Oral exams
Extended program
This course will provide the basic concepts of immunology necessary for understanding advanced next-generation cellular therapies, including:
- Innate and adaptive immunity;
- Mechanisms of cellular communication;
- Differentiation of immune cells;

Furthermore, concepts for the development of cell-based biological drugs will be covered, such as:
- Engineered immune cells for the treatment of solid or hematological tumors (CAR-T, CAR-NK, CAR-Mac);
- Vaccines based on dendritic cells or viral vectors;
- Engineered stem cells with viral vectors for the treatment of rare diseases;
- Extracellular vesicles as carriers of biotherapeutics.
Obiettivi Agenda 2030 per lo sviluppo sostenibile
Health and wellness
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