Unit APPLIED MOLECULAR VIROLOGY

Course
Biological sciences
Study-unit Code
A002584
Curriculum
Cellulare-molecolare
Teacher
Barbara Camilloni
Teachers
  • Barbara Camilloni
Hours
  • 42 ore - Barbara Camilloni
CFU
6
Course Regulation
Coorte 2021
Offered
2023/24
Learning activities
Affine/integrativa
Area
Attività formative affini o integrative
Academic discipline
MED/07
Type of study-unit
Opzionale (Optional)
Type of learning activities
Attività formativa monodisciplinare
Language of instruction
Italian
Contents
Virus structure, virus classification. Replication strategie of the viruses that infect humans: DNA viruses, positive-strand RNA viruses, negative-strand RNA viruses, duoble-stranded RNA-viruses and viruses that use a reverse trascriptase. Application fields of molecular virology: antiviral chemotherapy, viral vectors and vaccines.
Reference texts
Introduzione alla virologia moderna.
di Nigel J. Dimmock. Casa Editrice Ambrosiana
Educational objectives
The aim of the course is to provide the basic theoretical and practical notions of virology. In particular, issues related to the replication of the different viral families will be addressed by deepening the molecular aspect. The last part of the program will focus on applying this knowledge to the development of vaccines, antiviral drugs and the use of viruses as vectors.
Prerequisites
Basic knowledge of virology
Teaching methods
The course will be held through lectures in which the professor explains the basics, also through the aid of visual aids.
Other information
Attendance is not mandatory, but strongly recommended.
Learning verification modality
The student will have to take an oral test aimed at verifying: the ability to understand the main aspects concerning the topics covered during the course; the ability to autonomously elaborate connections between different topics, the quality of the oral exposition.
Extended program
Virus structure, virus classification. Replication strategie of the viruses that infect humans: DNA viruses (Adenovirus, Herpesvirus, Poxvirus), positive-strand RNA viruses (Picornavirus, Coronavirus, Flavivirus), negative-strand RNA viruses (Paramyxovirus, Orthomyxovirus, Filovirus), duoble-stranded RNA-viruses (Reobvirus) and viruses that use a reverse trascriptase (HBV, Retrovirus). Application fields of molecular virology: antiviral chemotherapy, viral vectors and vaccines.
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