Unit GENERAL PHARMACOLOGY AND PHARMACOGNOSY

Course
Pharmacy
Study-unit Code
65903806
Location
PERUGIA
Curriculum
In all curricula
Teacher
Maria Teresa Pallotta
Teachers
  • Maria Teresa Pallotta
Hours
  • 42 ore - Maria Teresa Pallotta
CFU
10
Course Regulation
Coorte 2023
Offered
2023/24
Learning activities
Caratterizzante
Area
Discipline biologiche e farmacologiche
Academic discipline
BIO/14
Type of study-unit
Obbligatorio (Required)
Type of learning activities
Attività formativa monodisciplinare
Language of instruction
Italian
Contents
General principles of Pharmacology. Pharmacodynamics: drug receptors and receptors / mechanisms.
Reference texts
R. Paoletti, S. Nicosia, F Clementi, G. Fumagalli
Farmacologia generale e molecolare, UTET, Torino
e
R. Paoletti, S. Nicosia, F Clementi, G. Fumagalli
Farmacologia clinica, UTET, Torino
Educational objectives
The course of Pharmacotherapy I, is the first of three teachings concerning Pharmacology. The main goal of education is to provide to the students the pharmacological basis for the understanding of the other two teachings, represented by Pharmacotherapy II and Toxicology. The Pharmacotherapy I is the study of the fundamentals of drug action that evaluates the relationship between body and drug, and analyzes the general mechanisms of interaction between the two systems. All the drugs share some general principles that are independent of the nature of the effect and which are common to all. The main knowledge gained will be related to:
1) Receptors and theories of receptor activation
2) mechanisms of drug action and signal transduction pathways.
Prerequisites
The student who is going to the course Pharmacotherapy I must have successfully passed the exams of General and Applied Biochemistry and Molecular Biology that are very important for understanding the contents of the course of Pharmacology and the general objectives of learning. It would also be very useful that the student had successfully passed the exam in General physiology, which would allow him to easily understand the path of a drug in the body. The knowledge of these topics is indispensable for the student who wants to follow the course with profit.
Teaching methods
Face-to-face teaching
Other information
Compulsory course attendance
Learning verification modality
multiple choise exsam
Extended program
General pharmacodynamics: targets and mechanisms of drug action; receptors, classification of mebrane receptors, intracellular receptors, dose-response curve; agonists, partial agonists, antagonists; individual variations (effects of age, pathological states, drug interactions, tolerance, placebo effects). General toxicity: side-effects, overdose, idiosyncratic and allergic reactions; teratogenesis and foetal toxicity; carcinogenesis; drug dependency
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