Unit PHARMACOLOGY AND PHARMACOTHERAPY I
- Course
- Pharmacy
- Study-unit Code
- A000525
- Location
- PERUGIA
- Curriculum
- In all curricula
- Teacher
- Paolo Puccetti
- CFU
- 12
- Course Regulation
- Coorte 2017
- Offered
- 2019/20
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa integrata
PHARMACOLOGY
| Code | A000526 |
|---|---|
| Location | PERUGIA |
| CFU | 6 |
| Teacher | Roberta Bianchi |
| Teachers |
|
| Hours |
|
| Learning activities | Caratterizzante |
| Area | Discipline biologiche e farmacologiche |
| Academic discipline | BIO/14 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian |
| Contents | Pharmacokinetics: disposition and metabolisms of drugs. Drug development, evaluation of new drugs and principles of therapeutics. |
| Reference texts | R. Paoletti, S. Nicosia, F Clementi, G. Fumagalli Farmacologia generale e molecolare, UTET, Torino e R. Paoletti, S. Nicosia, F Clementi, G. Fumagalli Farmacologia clinica, UTET, Torino |
| Educational objectives | The course of general pharmacology is the first of three teachings concerning Pharmacology. The main goal of education is to provide to the students the pharmacological basis for the understanding of the other two teachings, represented by Pharmacotherapy II Biological basis of biotechnologic drugs.. The general pharmacology is the study of the fundamentals of drug action that evaluates the relationship between body and drug, and analyzes the general mechanisms of interaction between the two systems. All the drugs share some general principles that are independent of the nature of the effect and which are common to all. The main knowledge gained will be related to: 1) absorption, distribution, metabolism and elimination of drugs 2) routes of administration of the drugs 3) bioavailability and bioequivalence 4) Receptors and theories of receptor activation 5) mechanisms of drug action and signal transduction pathways. The knowledge gained will enable the student to achieve the following skills: 1) be able to calculate the correct dosage of a drug 2) avoid toxic effects 3) rational use of medicines and achieve maximum efficacy with minimal toxicity |
| Prerequisites | To effectively follow and understand the topics covered in the course of Pharmacognosy is necessary for the student to have a basic knowledge of Plant Biology. The student who is going to the course Pharmacology, Pharmacognosy and Toxicology General must have successfully passed the exams of General and Applied Biochemistry and Molecular Biology that are very important for understanding the contents of the course of Pharmacology and the general objectives of learning. It would also be very useful that the student had successfully passed the exam in General physiology, which would allow him to easily understand the path of a drug in the body. The knowledge of these topics is indispensable for the student who wants to follow the course with profit. |
| Teaching methods | Face-to-face teaching |
| Other information | Compulsory course attendance |
| Learning verification modality | witten exam multple choise |
| Extended program | General pharmacokinetics: passages of drugs across cell membranes; routes of administration and absorption; bioavailability; distribution of drugs in the body; volume of distribution, binding to plasma proteins; drug metabolism; excretion; time-course of drug plasmatic contents (after single or repeated administration). |
PHARMACOTHERAPY I
| Code | 65007502 |
|---|---|
| Location | PERUGIA |
| CFU | 6 |
| Teacher | Paolo Puccetti |
| Teachers |
|
| Hours |
|
| Learning activities | Caratterizzante |
| Area | Discipline biologiche e farmacologiche |
| Academic discipline | BIO/14 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian |
| Contents | General principles of Pharmacology. Pharmacodynamics: drug receptors and receptor mechanisms of signal trasduction. |
| Reference texts | R. Paoletti, S. Nicosia, F Clementi, G. Fumagalli Farmacologia generale e molecolare, UTET, Torino |
| Educational objectives | The main objective of the course is to provide the student with the pharmacological basis for understanding the other two teachings. The general pharmacology is the study of the fundamentals of the action of drugs, that is, it evaluates the relationship between organism and drug and analyzes the general mechanisms of interaction between the two systems. All drugs share general principles of action that are independent of the nature of the effect and are common to all. The main knowledge acquired together with the other module will be related to: 1) receptors for drugs 2) receptor activation theories 3) signal transduction mechanisms 4) toxic effects and main toxicity mechanisms |
| Prerequisites | The student who is about to attend the Pharmacotherapy I course must have passed the animal and plant biology exam which are extremely important for understanding the contents of the Pharmacotherapy I course and the general learning objectives. Furthermore, it would be very useful if the student had successfully passed the General Physiology and Biochemistry exams. This would allow the student to easily understand the course of a drug within the organism and the general mechanisms of drug action. Knowledge of these topics is essential for the student who wants to take the course profitably. |
| Teaching methods | The course consists of classroom lectures on all topics of the course. |
| Other information | compulsory |
| Learning verification modality | multiple choice quiz |
| Extended program | General principles of pharmacodynamics: concept of receptor, its properties and types. Main classes of receptors: metabotropic and ionotropic receptors. Signal transduction mechanisms. Receptor study methods: study of dose-response curves, binding studies, molecular characterization studies. Receptor activation theories. Modulation of receptor responses. |