Unit GENERAL PHARMACOLOGY
- Course
- Biotechnology
- Study-unit Code
- 55058306
- Curriculum
- In all curricula
- Teacher
- Ursula Grohmann
- Teachers
-
- Ursula Grohmann
- Maria Teresa Pallotta (Codocenza)
- Hours
- 22 ore - Ursula Grohmann
- 20 ore (Codocenza) - Maria Teresa Pallotta
- CFU
- 6
- Course Regulation
- Coorte 2018
- Offered
- 2020/21
- Learning activities
- Affine/integrativa
- Area
- Attività formative affini o integrative
- Academic discipline
- BIO/14
- Type of study-unit
- Opzionale (Optional)
- Type of learning activities
- Attività formativa monodisciplinare
- Language of instruction
- Italian
- Contents
- Pharmacokinetics: the dynamic of drug absortion, distribution,
metabolism and elimination. Routes of administration
Pharmacodynamics
- Molecular drug targets
- Families of receptors and signaling pathways
- Quantitation of drug-receptor interaction and effects, radioligand binding method, molecular characterization (ion channels, G-proteincoupled receptor, receptor protein kinases, intracellular receptors).
- Transcription factors.
- Agonist and antagonist ligands
- Regulation of receptors
- Pharmacogenomics and pharmacogenetics
- Pharmacology of biotechnologic drugs - Reference texts
- Paoletti, Nicosia, Clementi, Fumagalli "Farmacologia generale e molecolare" UTET
- Educational objectives
- Biotechnologic competence - Knowledge and comprehension of the production, analysis and control of drugs obtained by means of biotechnologic processes; general principles of pharmacology in relationship to the project of drugs and in general of bioactive molecules obtained by means of biotechnologic processes; structura and biologic properties of animal and plant cells and tissues.
- Prerequisites
- Having passed the exams of Physiology and Biochemistry
- Teaching methods
- Face-to-face theoretical lessons
- Other information
- Private Facebook group FG-Biotec2020
- Learning verification modality
- Written exam with open answers
- Extended program
- Introduction to pharmacology
Concept of drug and medication
Chemical and physical properties of drugs
Pharmacokinetics: the dynamic of drug absorption, distribution, metabolism and elimination. Routes of administration
Pharmacodynamics
- Molecular drug targets
- Families of receptors and signalling pathways
- Quantitation of drug-receptor interaction and effects, radioligand binding method, molecular characterization (ion channels, G-protein-coupled receptor, receptor protein kinases, intracellular receptors).
- Transcription factors.
- Agonist and antagonist ligands
- Regulation of receptors
- Pharmacogenomics and pharmacogenetics
- Pharmacology of biotechnological drugs