Unit CELL THERAPY

Course
Biotechnology
Study-unit Code
55680306
Curriculum
In all curricula
Teacher
Maria Paola Martelli
Teachers
  • Maria Paola Martelli
Hours
  • 42 ore - Maria Paola Martelli
CFU
6
Course Regulation
Coorte 2018
Offered
2020/21
Learning activities
Affine/integrativa
Area
Attività formative affini o integrative
Academic discipline
MED/15
Type of study-unit
Opzionale (Optional)
Type of learning activities
Attività formativa monodisciplinare
Language of instruction
Italian
Contents
The blood functions and blood cells.
The bone marrow and hematopoiesis process
Stem cells. Classification. Stemness
The Hematopietic Stem cell
Techniques of cellular isolations: MACS AND FACS
Collection and processing of haematopoietic stem cells
Criopreservation
Transplant of hematopoietic stem cells: autologous, allogeneic and cord
blood
Dendritic cell. Vaccine therapy
Non trapiantologic cellular therapy: immunotherapy of tumours
Genic therapy
Clonation
Reference texts
Didattic material will be provided by the teacher
Educational objectives
Basic concepts on principles, technologies and ethical issues in Cell
therapy
Prerequisites
Knowledge on characteristics and functions of blood cells, in particular
cells involved in immunity
Teaching methods
face-to-face lessons and practice in the lab
Learning verification modality
Written examination: multiple choises
Extended program
The blood functions and blood cells.
The bone marrow and hematopoiesis process
Stem cells. Classification. Stemness
The Hematopietic Stem cell
Techniques of cellular isolations: MACS AND FACS
Collection and processing of haematopoietic stem cells
Modalità di verifica
dell'apprendimento
Esame scritto con domande a risposta multipla
Programma esteso Aspetti funzionali del sangue. Le cellule del sangue.
Il midollo osseo e l'emopoiesi.
La cellula staminale. Concetto di staminalità. Classificazione delle cellule
staminali
La cellula staminale emopoietica.
Raccolta e processazione delle cellule staminali emopoietiche
Tecniche di separazione cellulare: MACS e FACS
Criopreservazione
Trapianto di cellule staminali emopoietiche: autologo, allogenico, da
cordone ombelicale
La cellula dendritica.
Vaccinoterapia
Terapia cellulare non trapiantologica: immunoterapia dei tumori
Terapia genica
Clonazione
Criopreservation
Transplant of hematopoietic stem cells: autologous, allogeneic and cord
blood
Dendritic cell. Vaccine therapy
Non trapiantologic cellular therapy: immunotherapy of tumours
Genic therapy
Clonation
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