Unit ORGANIC CHEMISTRY

Course
Biotechnology
Study-unit Code
GP000516
Curriculum
In all curricula
CFU
6
Course Regulation
Coorte 2022
Offered
2022/23
Learning activities
Base
Area
Discipline chimiche
Academic discipline
CHIM/06
Type of study-unit
Obbligatorio (Required)
Type of learning activities
Attività formativa monodisciplinare

ORGANIC CHEMISTRY - Canale A

Code GP000516
CFU 6
Teacher Tiziana Del Giacco
Teachers
  • Tiziana Del Giacco
Hours
  • 47 ore - Tiziana Del Giacco
Learning activities Base
Area Discipline chimiche
Academic discipline CHIM/06
Type of study-unit Obbligatorio (Required)
Language of instruction Italian
Contents The fundamentals of organic chemistry. Functional groups. Isomerism and principles of stereochemistry. Mechanisms of fundamental organic reactions.
Classes of organic compounds: alkanes and cycloalkanes, alkenes, halogen alkanes, aromatic compounds, alcohols, phenols, ethers, carboxylic acids and derivatives, heterocyclic compounds, carbohydrates. amino acids. For each class of compounds the following aspects will be treated: nomenclature, physical properties, preparations, main reactions and practical applications.
Reference texts Introduzione alla Chimica Organica- William H. Brown e Thomas Poon-EdiSES UNIVERSITÀ

Chimica Organica- Un approccio Biologico- John McMurry- Zanichelli.

Eserciziario di Chimica Organica F. Nicotra, L. Cipolla - Edises
Educational objectives This course represents an introduction to Organic Chemistry. The main aim of this course is to provide the students with the conceptual tools that will allow them to understand the chemical behavior of the organic matter, and the bases to comprehend the nature and the functioning of biological systems.
Main knowledge acquired will be:
- knowledge concerning the atomic structure and the chemical bonds;
- knowledge about the molecular structure and its influence on physical properties and intermolecular interactions;
- the concept of functional group;
- the nomenclature of organic compounds;
- chemical properties and reactivity of the main classes of organic compounds (alkanes, alkenes, alkynes, alkyl halides, alcohols, aromatic compounds, aldehydes, ketones, carboxylic acids and derivatives);
- elements of stereochemistry.
The main competences (i.e. the ability to apply the acquired knowledge) will be:
- being able to draw the chemical structure of an organic molecule from its name;
- being able to assign the name of an organic molecule given its chemical structure;
- being able to predict the chemical behavior of organic molecules, on the basis of their functional groups;
- being able to plan multistep syntheses of simple organic molecules.
Prerequisites In order to understand and know how to develop the concepts explained in the course it is necessary to have successfully supported the examination of General and Inorganic Chemistry with Stoichiometry Elements.
Teaching methods The course is organized as follows:
- lectures on all topics of the course;
- trining by solving problems related to the carried out programò.
Other information
Learning verification modality The exam includes an oral examination.

The oral test consists of an interview lasting about fourty minutes aimed at ascertaining the level of knowledge and understanding reached by the student on the theoretical and methodological implications mentioned in the program. The oral exam will also verify the language property of the student and his ability to express.
Extended program Organic chemistry and life. The chemical bonds. The molecules of organic chemistry. Concept of functional group. Molecular structure and physical properties. Intermolecular interactions. Alkanes and cycloalkanes: Structure, nomenclature, physical properties and main chemical reactions. Alkenes: Structure, nomenclature, preparation and reactivity. The reaction of electrophilic addition. Principles of stereochemistry: Elements of symmetry, chiral compounds, nomenclature R / S, meso compounds. Optical activity, the polarimeter. Stereochemistry of some reactions. Conformational analysis. Halogen alkanes: structure, nomenclature, preparation and reactivity. Aliphatic nucleophilic substitution reactions SN1 and SN2 and elimination reactions. Aromatic compounds: aromaticity concept, structure, nomenclature and reactivity. The reaction of electrophilic and nucleophilic substitution of aromatic compounds. Red-Ox reactions in organic chemistry. Alcohols, phenols and ethers: structure, nomenclature and reactivity. Elimination, oxidation and acidity. The carbonyl compounds, the characteristics of the C = O functional group. Aldehydes and ketones: structure, nomenclature, preparation and reactivity; acyl nucleophilic addition, hemiacetals and acetals keto-enol tautomerism and aldol condensation. Carboxylic acids: structure and reactivity nomenclature. Acidity. Derivatives of carboxylic acids: acyl halides, anhydrides, esters and amides. Nucleophilic acyl substitution reactions. Reactions of alpha-substitution and condensation of the carbonyl group: keto-enol tautomerism. Heterocyclic compounds with rings to five and six atoms. Carbohydrates. Amino acids.

ORGANIC CHEMISTRY - Canale B

Code GP000516
CFU 6
Teacher Stefano Santoro
Teachers
  • Stefano Santoro
Hours
  • 47 ore - Stefano Santoro
Learning activities Base
Area Discipline chimiche
Academic discipline CHIM/06
Type of study-unit Obbligatorio (Required)
Language of instruction Italian
Contents The course is an introduction to Organic Chemistry, focused on the study of the structures, properties and reactivity of organic matter.
Reference texts Chimica Organica - Un approccio Biologico - J. McMurry - Zanichelli
Chimica Organica - T. W. G. Solomons, C. B. Fryhle - Zanichelli
Chimica Organica - P. Y. Bruice - Edises
Educational objectives This course represents an introduction to Organic Chemistry. The main aim of this course is to provide the students with the conceptual tools that will allow them to understand the chemical behavior of the organic matter, and the bases to comprehend the nature and the functioning of biological systems.
Main knowledge acquired will be:
- knowledge concerning the atomic structure and the chemical bonds;
- knowledge about the molecular structure and its influence on physical properties and intermolecular interactions;
- the concept of functional group;
- the nomenclature of organic compounds;
- chemical properties and reactivity of the main classes of organic compounds (alkanes, alkenes, alkynes, alkyl halides, alcohols, aromatic compounds, aldehydes, ketones, carboxylic acids and derivatives);
- elements of stereochemistry.
The main competences (i.e. the ability to apply the acquired knowledge) will be:
- being able to draw the chemical structure of an organic molecule from its name;
- being able to assign the name of an organic molecule given its chemical structure;
- being able to predict the chemical behaviour of organic molecules, on the basis of their functional groups;
- being able to plan multistep syntheses of simple organic molecules.
Prerequisites In order to be able to understand the topics of the course you must have successfully passed the Chimica Generale e Inorganica con Elementi di Stechiometria exam.
Teaching methods The course is organized as follows:
- lectures on all the subjects of the course;
- classroom exercises on program topics already discussed in the theoretical lectures;
- laboratory training. The students will performs simple practical laboratory tasks individually or in small groups. The laboratory experiences will be preceded by a lecture presentation.
Other information -
Learning verification modality The exam consists in a written test and an oral test.
The written test requires providing the solution to exercises and answering theoretical questions, and will require no more than two hours. The test is designed to evaluate the ability to apply theoretical knowledge to solve problems, the ability to understand the proposed problems and the ability to communicate in written form.
The oral test consists in an interview of about 30 minutes aiming at the assessment of the level of knowledge and ability of understanding reached by the student on the theoretical and methodological contents as indicated in the program. The oral test will also test the student communication skills and his ability in organizing the exposure of the theoretical topics.
Extended program Organic chemistry and life. The chemical bonds. The molecules of organic chemistry. Concept of functional group. Molecular structure and physical properties. Intermolecular interactions. Alkanes and cycloalkanes: structure, nomenclature, physical properties and main chemical reactions. Alkenes: structure, nomenclature, preparation and reactivity. Electrophilic addition. reactions Principles of stereochemistry: elements of symmetry, chiral compounds, R/S nomenclature, meso compounds. Optical activity, the polarimeter. Stereochemistry of some reactions. Conformational analysis. Haloalkanes: structure, nomenclature, preparation and reactivity. Nucleophilic aliphatic substitution reactions: SN1 and SN2. Elimination reactions. Aromatic compounds: aromaticity concept, structure, nomenclature and reactivity. The reaction of electrophilic and nucleophilic substitution of aromatic compounds. Redox reactions in organic chemistry. Alcohols, phenols and ethers: structure, nomenclature and reactivity. Elimination, oxidation and acidity. The carbonyl compounds, the characteristics of the C=O functional group. Aldehydes and ketones: structure, nomenclature, preparation and reactivity; acyl nucleophilic addition, hemiacetals and acetals, keto-enol tautomerism and aldol condensation. Carboxylic acids: structure, reactivity, nomenclature, acidity. Derivatives of carboxylic acids: acyl halides, anhydrides, esters and amides. Nucleophilic acyl substitution reactions. Reactions of alpha-substitution and condensation of the carbonyl group: keto-enol tautomerism. Heterocyclic compounds with 5- and 6-membered rings. Carbohydrates. Amino acids.
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