Unit BIOCOMPATIBLE MATERIALS, BIOMASS AND SUSTAINABILITY

Course
Molecular and industrial biotechnology
Study-unit Code
A003501
Curriculum
In all curricula
Teacher
Assunta Marrocchi
CFU
12
Course Regulation
Coorte 2023
Offered
2023/24
Type of study-unit
Obbligatorio (Required)
Type of learning activities
Attività formativa integrata

BIOCOMPATIBLE MATERIALS FOR BIOTECHNOLOGY APPLICATIONS

Code A003502
CFU 6
Teacher Assunta Marrocchi
Teachers
  • Assunta Marrocchi
Hours
  • 42 ore - Assunta Marrocchi
Learning activities Caratterizzante
Area Discipline chimiche
Academic discipline CHIM/06
Type of study-unit Obbligatorio (Required)
Language of instruction Italian
Contents Biomaterials & Biocompatibility. Polymeric, ceramic and metallic biomaterials. Composites. Analytical methods for biomaterials surface characterization. Surface modification of biomaterials. Established biomaterials-based technologies. Bioelectronics.
Reference texts -Power point slides and scientific articles will be provided
SUGGESTED TEXTBOOKS:
-L. Stanciu, S. Diaz-Amaya ‘’Introductory Biomaterials. An overview of key concepts’’. 1st edition. Academic Press, 2021.
-C. Di Bello, A. Bagno ‘’Biomateriali. Dalla scienza dei materiali alle applicazioni cliniche’’. 2° edizione. Patròn Editore, 2016
-A. Marrocchi Ed. “Sustainable strategies in organic electronics” (I Ed., 2022) – Woodhead Publishing, Elsevier [ISBN 978-0-12-823147-0]
Educational objectives The main objective of the course is to provide to students the basic knowledge about chemical-physical aspects and the development of biocompatible materials, to rationally elaborate selection criteria for their design/use in the fields of application discussed during lectures.
The main knowledge acquired will be:
-knowledge of (i) definition of biomaterial and biocompatibility (ii) definition of solid state, main crystalline networks and their principal defects;
-basic knowledge of the electrical, optical, thermal properties of solid materials;
-knowledge of the fundamental concepts of stress, strain, rigidity, resistance, toughness of biocompatible materials;
-knowledge of the main classes of biocompatible materials: Polymers (classification on the basis of their chemical-physical and mechanical properties; polymerization reactions; main classes of interest); Ceramics and glass-ceramics (traditional and advanced materials); Metals and alloys; Composites;
-basic knowledge of their main production techniques and influence of these latter on the operational material behavior;
-knowledge of the biomaterials corrosion phenomena in a biological environment and relative issues;
-knowledge of the main instrumental techniques for the study of biomaterials surface, to evaluate their biocompatibility;
-knowledge of the main techniques for biomaterials surface modification, to adjust biocompatibility;
-basic knowledge of selected biomaterials-based sensors for application in medical and biological field.
The main abilities will be:
-ability in elaborating criteria of choice for the design and synthesis of 3D structures to be employed in the field discussed during lectures. -ability in identifying the most suitable instrumental techniques for the characterization of biomaterials surfaces, in view of evaluating their biocompatibility
-ability in identifying the most suitable techniques for biomaterials surface modification, in view of improving their biocompatibility.
Prerequisites none
Teaching methods Face-to-face lectures on all the topics of the course.
During the course there might be the possibility to organize seminars in which external experts will report about their practical experience on the use of advanced instrumental techniques for the study of biomaterials surfaces.
Learning verification modality The course constitutes a module of the integrated course 'BIOMATERIALS, BIOMASSES, AND SUSTAINABILITY.' It is worth noting that the final assessment for learning remains the same for both modules that make up the integrated course, although partial assessments are possible. In the specific case of this module, the partial assessment consists of an oral examination. This examination involves a discussion lasting approximately 30 minutes, aimed at evaluating the level of competence and knowledge acquired by the student regarding the program's content. Furthermore, through the oral examination, the student's ability to analyze the same content will be assessed, both in terms of language proficiency and presentation organization. Both the knowledge and skills acquired and the ability to analyze the content discussed in class are considered essential for the students' professional development.
Students with disabilities and/or specific learning disabilities (SLD) are invited to visit the dedicated page on the tools and measures provided and to prearrange any necessary accommodations with the instructor (https://www.unipg.it/disabilita-e-dsa)
Extended program Biomaterials & Biocompatibility. Reference to the main types of chemical bonding. Solid state. Solid materials properties (mechanical, thermal, optical). Polymeric, ceramic/glass-ceramic and metallic biomaterials: classification, synthesis, production tecniques, main classes of interest. (nano)Composites. Established biomaterials-based technologies. Main analytical methods for biomaterials surface characterization. Surface modification of biomaterials. Bioelectronics. Other emerging and future biomaterials-based technologies. Reference to the existing normative.
Obiettivi Agenda 2030 per lo sviluppo sostenibile 3, 9

SUSTAINABLE BIOMASS TRANSFORMATION PROCESSES

Code A003503
CFU 6
Teacher Luca Sancineto
Teachers
  • Luca Sancineto
Hours
  • 42 ore - Luca Sancineto
Learning activities Caratterizzante
Area Discipline chimiche
Academic discipline CHIM/06
Type of study-unit Obbligatorio (Required)
Language of instruction Italian
Contents Renewable resources for processes to access energy, fine chemicals and plastics: Biomass. Biomass types. Biorefineries. Processes for the biomass valorization finalized to the preparation of biofuels, bio-chemicals, bioplastics. Green chemistry and biorefineries. Alternative solvents. Heterogenized and heterogeneous catalysts. Microwaves as alternative heating source. Renewables industries: some examples.
Reference texts -Educational material distributed during the lectures
-J. Clark, F. Deswarte (Eds) “Introduction to Chemicals from Biomass”, 2015 John Wiley & Sons
Educational objectives The main objective of the course is to provide to students the basic knowledge to rationally elaborate criteria of choice criteria of choice to improve synthetic processes by using the so-called 12 Green Chemistry principles as guidelines , with particular reference to the current technologies for vegetal biomass transformations into bioenergy, biochemicals, bioplastics.The main knowledge acquired will be: -knowledge of the biomass definition-knowledge of the main types of biomass, with particular reference to vegetal biomass. -knowledge of the biorefinery and of the “platform molecule” concepts-knowledge of the main technologies of pre-treatment for the vegetal biomass, preliminary to the diverse conversion processes.-knowledge of the main characteristics of the thermochemical processes, i.e. combustion, gasification and pyrolysis-knowledge of the main catalytic technologies for the upgrade of those platform molecules examined in-depth during lectures into biofuels, biochemicals, bioplastics.- Acquisition of the Green Chemistry basic concepts and the main strategies to realize eco-compatible synthetic processes for vegetal biomass valorization-The main abilities will be: -ability in recognizing the proper type of vegetal biomass to dedicate to the production of bioenergy, biochemicals and bioplastics, respectively-ability in developing the concept of biorefinery-ability in identifying similarities and differences between the thermochemical conversion technologies of lignocellulosic biomass-ability in identifying critical issues in the current processes for vegetal biomass transformation and elaborating criteria of choice for the use of Green Chemistry principles, to obtain improvements in terms of environmental impact and sustainability
Prerequisites none
Teaching methods Face-to-face lectures on all the topics of the course
Learning verification modality The course is part of the integrated program 'BIOMATERIALS, BIOMASSES, AND SUSTAINABILITY.' It should be noted that the final assessment of learning remains the same for both modules that make up the integrated course, although partial assessments are possible. In the specific case of this module, the partial assessment consists of an oral examination. This examination involves a discussion lasting approximately 30 minutes, aimed at assessing the level of competence and knowledge achieved by the student regarding the program's content. Furthermore, through the oral examination, the ability to process the same content will be evaluated, both in terms of language proficiency and presentation organization. Both the knowledge and skills acquired and the ability to process the content discussed in class are considered essential for the professional development of students.

Students with disabilities and/or specific learning disabilities (SLD) are invited to visit the dedicated page outlining the tools and measures provided and to coordinate any necessary accommodations in advance with the instructor (https://www.unipg.it/disabilita-e-dsa).
Extended program Introduction. Renewable resources for processes to access energy, fine chemicals and plastics: Biomass. Biomass types. Major vegetal biomass components. Biorefineries. Chemical processes for the biomass valorization finalized to the preparation of biofuels, bio-chemicals, bioplastics via “platform molecules”. Green chemistry and biorefineries. The 12 Green Chemistry principles. Metrics. Main strategies for the realization of eco-compatible chemical processes for biomass transformation. Alternative solvents: water, immobilized solvents, ionic liquids and eutectic mixtures, fluorinated solvents, biomass-derived solvents, solvent-free conditions, supercritical fluids. Heterogenized and heterogeneous catalysts. Microwaves as alternative heating source. Renewables industries: some examples.
Obiettivi Agenda 2030 per lo sviluppo sostenibile 7,9,12
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