Unit GENERAL PATHOLOGY
- Course
- School of dental medicine
- Study-unit Code
- 50511007
- Curriculum
- In all curricula
- Teacher
- Luigina Romani
- Teachers
-
- Luigina Romani
- Hours
- 42 ore - Luigina Romani
- CFU
- 7
- Course Regulation
- Coorte 2018
- Offered
- 2019/20
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa monodisciplinare
- Language of instruction
- Italian
- Contents
- Health status and disease concept
Etiology and pathogenesis
Causes of disease
Progressive and regressive processes
Cellular death
Inflammation
Immunology and immunopathology
Autoimmunity. Acute and chronic inflammatory diseases of the oral cavity
Oncology
Molecular basis
Molecular oncology for diagnostic, prognostic and therapeutic applications
Pathophysiology of organs and systems that are relevant for the stomatognathic system: blood, heart and circulation, respiratory and digestive systems. - Reference texts
- G.M. Pontieri, M.A. Russo, L. Frati - Patologia Generale, Piccin Editore
Robbins e Cotran. Le basi patologiche delle malattie, 1° vol., Elsevier Editore - Educational objectives
- Knowledge of the main causes (chemical, physical and biological) responsible for the alterations of the body’s structures and functions
Knowledge of the pathomechanisms leading to biological damage
Knowledge of the host reactive processes to different infectious and non-infectious noxae that are crucial in the process of healing /repair or immunopathology, with particular emphasis on mechanisms of immunity, inflammation, wound healing, repair and chronic inflammation.
Analysis of oral diseases and their relationship to systemic diseases. - Prerequisites
- The course requires basic knowledge of Biochemistry and Molecular Cell Biology, Genetics, Anatomy, Histology.
- Teaching methods
- Frontal lessons
- Other information
- Learning verification modality
- Oral exam
- Extended program
- Health status and disease concept.
Etiology and pathogenesis.
Causes of disease: endogenous and exogenous factors, physical, chemical, biological and microbiological causes. Hyper- and hypo-vitaminosis.
Cellular and molecular pathology, genetics pathology, congenital pathology and theratogenesis.
Progressive and regressive processes: intracellular and extracellular degenerations. The cellular "Stress". Damage by hypoxia and defects of cellular respiration. Atrophy, hypertrophy.
Cell death: necrosis, apoptosis and autophagy.
Inflammation: mediators of acute inflammation. Hyperemia. Systemic signs of inflammation. Fever. Exudates. Wheal. Edema. Ascites. Abscess. Phlegmon. Septicemia. Empyema. Pustule. The complement system. Kinins, cytokines and prostaglandins. Blood count. The inflammatory cells. Chemotaxis and phagocytosis. Differential WBC. Leucocytosis and leucopenia. Mediators of chronic inflammation. Granulomas. Wound healing and repair processes. Fibrosis and sclerosis.
Immunology and immunopathology. The immune system. The innate and adaptive immune response. Cells and receptors of the innate immunity.
T and B lymphocytes. Antigens and antibodies. Hypersensitivity. Autoimmunity. Acute and chronic inflammatory diseases of the oral cavity.
Oncology. Regulation of cell growth. Receptors, signal transduction and genes.
Disorders of growth of non-tumoral cells. Tumors’ morphology. Benign and malignant tumors. Nomenclature and classification of tumors. History of cancer (initiation, promotion and progression).
Molecular basis: oncogenes and anti-oncogenes. The Chemical, physical and viral carcinogenesis. Invasiveness and metastasis.
Molecular oncology for diagnostic, prognostic and therapeutic applications.
Pathophysiology of organs and systems that are relevant for the stomatognathic system: blood, heart and circulation, respiratory and digestive systems.
GENERAL PATHOLOGY
| Code | 50511007 |
|---|---|
| CFU | 3 |
| Teacher | Luigina Romani |
| Learning activities | Caratterizzante |
| Area | Discipline mediche di rilevanza odontoiatrica |
| Academic discipline | MED/04 |
| Type of study-unit | Obbligatorio (Required) |
GENERAL PATHOLOGY
| Code | 50511007 |
|---|---|
| CFU | 4 |
| Teacher | Luigina Romani |
| Learning activities | Caratterizzante |
| Area | Discipline mediche di rilevanza odontoiatrica |
| Academic discipline | MED/04 |
| Type of study-unit | Obbligatorio (Required) |