Unit BIOCHEMISTRY AND MOLECULAR BIOLOGY

BIOCHEMISTRY

Code	GP003685
CFU	5
Teacher	Lara Macchioni
Teachers	Lara Macchioni
Hours	30 ore - Lara Macchioni
Learning activities	Base
Area	Struttura, funzione e metabolismo delle molecole d'interesse biologico
Academic discipline	BIO/10
Type of study-unit	Obbligatorio (Required)

Clinical biochemistry and Clinical Molecular Biology

Code	50585801
CFU	1
Teacher	Barbara Cellini
Teachers	Barbara Cellini
Hours	6 ore - Barbara Cellini
Learning activities	Caratterizzante
Area	Diagnostica di laboratorio
Academic discipline	BIO/12
Type of study-unit	Obbligatorio (Required)
Language of instruction	Italian
Contents	Definition of Clinical Biochemistry. Evaluation of clinical analyses. Basic diagnostic tests. Glucose homeostasis and diabetes. Serum enzymes. Tumor Markers. Hemochromocytometric examination. Urinary profile.
Reference texts	Introduzione alla Biochimica Patologica e Clinica - Lauro Galzigna – PICCIN Elisabetta Albi-Biochimica clinica essenziale Ed. Zanichelli
Educational objectives	The acquired knowledge will be:   Basic general knowledge of clinical and molecular biochemistry
Prerequisites	For an effective understanding of the topics of Clinical Biochemistry and clinical Molecular Biology, the basic knowledge of biochemistry and molecular Biology is required.
Teaching methods	The course is organized as follows: -lectures on all the subjects. Students are stimulated to interact with the teacher during the lectures.
Other information	Perugia-School of Medicine-S. Andrea delle Fratte
Learning verification modality	The exam consists of an oral examination relative to the modules of the integrated course
Extended program	Definition of Clinical Biochemistry. Evaluation of analyrical quality: precision, accuracy, sensitivity, specificity, linearity. Predictive value. Pre-analytic variability. Pre-laboratory variability. Basic diagnostic analyses. Biochemical profile. Glucose homeostasis and hormone regulation. Diabetes. Glycemia. Methods of determination of glucose. Study of plasma proteins to obtain information on the state of health. Protein electrophoresis. Enzymes (outline): classification. Isozymes. Hepatic, muscular, cardiac, pancreatic, prostate and bone enzymes. Method of measurement of enzymatic activities. Tumor markers (overview): concept of an ideal marker. Humoral and tissue markers. Hemochromocytometric examination (outline). Urinary profile.

MOLECULAR BIOLOGY

Code	50595802
CFU	2
Teacher	Lara Macchioni
Teachers	Lara Macchioni
Hours	12 ore - Lara Macchioni
Learning activities	Base
Area	Struttura, funzione e metabolismo delle molecole d'interesse biologico
Academic discipline	BIO/11
Type of study-unit	Obbligatorio (Required)