Unit APPLIED BIOLOGY AND GENERAL AND METABOLIC BIOCHEMISTRY
- Course
- Exercise and sport science
- Study-unit Code
- A001863
- Curriculum
- In all curricula
- CFU
- 11
- Course Regulation
- Coorte 2022
- Offered
- 2022/23
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa integrata
GENERAL AND METABOLIC BIOCHEMISTRY
| Code | A001865 |
|---|---|
| CFU | 6 |
| Teacher | Mirco Dindo |
| Teachers |
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| Hours |
|
| Learning activities | Base |
| Area | Biomedico |
| Academic discipline | BIO/10 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian |
| Contents | Protein metabolism, enzymes, glucose metabolism, citric acid cycle, lipid metabolism, amino acids metabolism, oxidative phosphorylation, role of hormones in metabolism. |
| Reference texts | Di Giulio, Fiorilli, Stefanelli: "Biochimica per le scienze motorie" Casa editrice Ambrosiana David L Nelson, Michael M Cox: "Introduzione alla biochimica di Lehninger" Zanichelli Franco Salvatore "Biochimica Umana" Idelson Gnocchi |
| Educational objectives | The main goal of the course is to provide students with the foundation for understanding the mechanisms that regulate metabolism. The main competences acquired will be: -Preparatory biochemistry - Basics of structural biochemistry - Basics of functional biochemistry - Understanding of the metabolism - Understanding of the muscular metabolism |
| Prerequisites | The understanding of most of the topics requires the knowledge of Biology. Knowledge of these issues is a prerequisite for the student who wants to follow the course with profit. |
| Teaching methods | Lectures on all subjects of the course |
| Other information | |
| Learning verification modality | Written (multiple choice) exams consisting of questions covering all the topics addressed during the course aimed to demonstrate student's understanding of the main theme of biological chemistry applied to Sport science and physical education. |
| Extended program | General concepts of inorganic and organic chemistry; Amino acids, proteins (primary structure, secondary structure, tertiary structure, quaternary structure), protein folding, hemoglobin, enzymes, carbohydrates, lipids, biological membranes, signaling pathways. Glucose metabolism, citric acid cycle, lipid metabolism, amino acids metabolism, oxidative phosphorylation, Hormonal regulation of metabolisms. Energy systems, biochemical structure of muscle, muscle contraction, muscle metabolism. |
APPLIED BIOLOGY
| Code | A001864 |
|---|---|
| CFU | 5 |
| Teacher | Rita Romani |
| Teachers |
|
| Hours |
|
| Learning activities | Base |
| Area | Biomedico |
| Academic discipline | BIO/13 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian |
| Contents | Biological and chemical basis of life and molecular organization. Structure and function of the plasma membrane. Cell wall and extracellular matrix: structure, function and interaction of cells with the extracellular environment and cells between them. Cell communication: cell signaling and signal transduction. Cytoplasmic membrane systems: structure, function, and membrane trafficking. The mitochondria and cellular respiration. Cancer. General genetics. |
| Reference texts | Biochimica e Biologia per le professioni sanitarie casa editrice McGraw-Hill autori Roberti, Bistocchi, Antognelli, Talesa -Biologia e Genetica EDISES autori De Leo, Ginellli, Fasano - L'essenziale di biologia molecolare della cellulaAlberts B., Johnson A.,Lewis J., et al. Zanichelli -"Elementi di Biologia e Genetica"WK Purves, D Sadava, GH Orians, HC Heller . Zanichelli - Fondamenti di Biologia Solomon; Martin; Martin; Berg casa editrice EdiSES |
| Educational objectives | Objective of the course is the integrated study of the cell and of living organisms, with particular regard to the mechanisms involved in the biogenesis of organelles and cellular structures, interactions between cells and between cells and the extracellular environment, synthesis and transmission of genetic information, gene expression mechanisms, cell proliferation, bases of genetics. |
| Prerequisites | To achieve the training objectives, the student requires a minimum knowledge of Chemistry. |
| Teaching methods | Face-to-face theoretical lessons with the use of powerpoint slides |
| Learning verification modality | The exam consists of a written test followed by an oral test. oral exam consisting of an about 10-minute discussion aimed at ascertaining the degree of comprehension of the student about theoretical and methodological contents of the program |
| Extended program | The biological organization. Characteristics of living organisms. Prokaryotic and eukaryotic cells. Virus. The chemical basis of life. Biological macromolecules: proteins, nucleic acids, lipids, carbohydrates. The cell membrane: structure and function with particular reference to transport mechanisms and cellular communication. The various types of receptors and signal transduction pathways. The nucleus and nucleolus: structure and function. Organization of chromatin, chromosomes. Characteristics of the eukaryotic gene. Gene expression: transcription and its regulation. Editing of primary transcripts. Gene expression: Characteristics of the genetic code and its operation. Translation and its control. Smooth and rough endoplasmic reticulum. Golgi apparatus, lysosomes and peroxisomes. Vesicle trafficking and sorting of proteins. The mitochondria and cellular respiration. Cell cycle and its control. Interphase, DNA replication, mitosis. Mutations. Oncogenes and tumor suppressor. Reproduction of multicellular organisms: Meiosis and gametogenesis. Definitions and meaning of a gene locus, allele, haploid, diploid genotype, phenotype, homozygous, heterozygous, dominant and recessive. Mendel's laws and their interpretation. Extensions to Mendelian analysis. Inheritance: generality and mode of transmission. Normal and pathological human karyotype |