Unit MICROBIOLOGY

Course
Medicine and surgery
Study-unit Code
GP005687
Location
PERUGIA
Curriculum
In all curricula
CFU
7
Course Regulation
Coorte 2017
Offered
2018/19
Type of study-unit
Obbligatorio (Required)
Type of learning activities
Attività formativa integrata

MICROBIOLOGY - MOD. 1

Code GP005792
Location PERUGIA
CFU 2
Learning activities Caratterizzante
Area Patologia generale e molecolare, immunopatologia, fisiopatologia generale, microbiologia e parassitologia
Academic discipline MED/07
Type of study-unit Obbligatorio (Required)

Cognomi A-L

CFU
2
Teacher
Stefano Perito
Teachers
  • Stefano Perito
Hours
  • 24 ore - Stefano Perito
Language of instruction

Italian language
Contents

General bacteriology, differences between prokaryotes (bacteria), and eukaryotes (protozoa, fungi).
General characteristics, basic and optional structures of the beating cell, metabolism, nutrition, bacterial genetics, bacterial pathogenesis, Antibiotics, chemotherapeutics, antibiogram, vaccines, sera, disinfection and sterilization.
Reference texts

Murray PR et al, Medical Microbiology, 8th edition. EDRA editor
Educational objectives

The knowledge of:
cellular and molecular bases of microbial pathogenicity,
of interactions between microorganism and host,
the causes and mechanisms of onset of the main diseases of bacterial, fungal, viral and parasitic etiology
biotechnology applications in diagnosis, prophylaxis and antimicrobial chemotherapy.
Prerequisites

Basic knowledge of Biology, Anatomy and Immunology.
Teaching methods

Frontal lessons
Other information

Traineeship activities, practical exercises in the laboratory and tutorial activities.
Learning verification modality

Oral examen
Extended program

Presentation of the course, Differences between prokaryotes / eukaryotes Gram + cell wall
Gram-cell wall,
Optional facilities Metabolism, Nutrition, Growth curve
Culture media for bacteria
Genetics of bacteria.
Genetic exchange between bacteria. Contagion and transmission of microorganisms
Bacterial pathogenesis Bacterial pathogenesis
Vaccines, Antibiotic Serums Antibiogram, Sterilization, Disinfection

Cognomi M-Z

CFU
2
Teacher
Elio Cenci
Teachers
  • Elio Cenci
Hours
  • 24 ore - Elio Cenci
Language of instruction
Italian
Reference texts

Murray PR, Rosenthal KS, Pfaller MA. Microbiologia Medica, ottava edizione, Edra Masson

Sherris Microbiologia Medica, 2012, EMSI Editore
Educational objectives

To provide the Medicine and Surgery Degree students the knowledge of Microbiology
able to guarantee the skills and competences required to achieve the essential levels of professional service.
The knowledge of the basic and optional structures of the prokaryotic and eukaryotic cells. Pathogenesis, genetic exchange between bacteria, control strategies of bacterial, viral, fungal and parasitic diseases.
Teaching methods

Face to face lessons
Clinical Microbiology Laboratory
Learning verification modality

Oral examination
Extended program

Presentation of the course, differences between Prokaryotes / Eukaryotes

Cell wall of Gram +

Cell wall of Gram-bacteria,

Optional frames

Metabolism, Nutrition, Growth curve

Genetics of bacteria

Transmission and Pathogenesis

Virulence factors of bacteria (adhesins, exoenzymes, capsule, toxins)

Vaccines, immune sera

Antibiotics

Disinfection and Sterilization

MICROBIOLOGY - MOD. 2

Code GP005793
Location PERUGIA
CFU 1
Learning activities Caratterizzante
Area Patologia generale e molecolare, immunopatologia, fisiopatologia generale, microbiologia e parassitologia
Academic discipline MED/07
Type of study-unit Obbligatorio (Required)

Cognomi A-L

CFU
1
Teacher
Stefano Perito
Teachers
  • Stefano Perito
Hours
  • 12 ore - Stefano Perito
Language of instruction

Italian language
Contents

Special Bacteriology: The main bacteria that cause diseases in humans. Staphylococci, Streptococci, Enterobacteriaceae, Neisserie, Clostridium, Corynebacterium, Treponema, Chlamidiae, Legionella, Helycobacter et a
Reference texts

Murray PR, Medical Microbiology, 8th edition, EDRA publisher. 2017
Educational objectives

The knowledge of:
cellular and molecular bases of microbial pathogenicity,
of interactions between microorganism and host,
the causes and mechanisms of onset of the main diseases of bacterial, fungal, viral and parasitic etiology
biotechnology applications in diagnosis, prophylaxis and antimicrobial chemotherapy.
Prerequisites

Knowledge of General Bacteriology, Immunology, Biology, Anatomy
Teaching methods

Frontal lessons
Other information

Practical exercises, outpatient training activities, tutoring activities
Learning verification modality

Face to face
Extended program

Classification of bacteria, Staphylococci Streptococci
Streptococci Corynebacterium
Clostridia Clostridia
Salmonella E.coli
Neisserie
Vibrio Cholerae
Pseudomonas Legionella
Helicobacter Mycobacterium
Mycobacterium Mycoplasma, Ureaplasma
Chlamydia treponema

Cognomi M-Z

CFU
1
Teacher
Elio Cenci
Teachers
  • Elio Cenci
Hours
  • 12 ore - Elio Cenci
Language of instruction
Italian
Reference texts

Murray PR, Rosenthal KS, Pfaller MA. Microbiologia Medica, settima edizione, Edra Masson

Sherris Microbiologia Medica, 2012, EMSI Editore
Educational objectives

To provide the Medicine and Surgery Degree students the knowledge of Microbiology
able to guarantee the skills and competences required to achieve the essential levels of professional service.
The knowledge of the principal bacteria responsible of infectious diseases and of their pathogenetic mechanisms.
Teaching methods

Face to face lessons
Learning verification modality

Oral examination
Extended program

Staphylococcus (S. aureus, S. epidermidis, S. saprophyiticus)
Streptococcus (S. pyogenes, S. pneumoniae, S. mutans, S. agalactiae), enterococchi
Neisseria gonorrhoeae, N. meningitidis
Corynebacterium diphtheriae

MICROBIOLOGY - MOD. 3

Code GP005794
Location PERUGIA
CFU 1
Learning activities Caratterizzante
Area Patologia generale e molecolare, immunopatologia, fisiopatologia generale, microbiologia e parassitologia
Academic discipline MED/07
Type of study-unit Obbligatorio (Required)

Cognomi A-L

CFU
1
Teacher
Stefano Perito
Teachers
  • Stefano Perito
Hours
  • 12 ore - Stefano Perito
Language of instruction

Italian language
Contents

General virology, the main virua to RNA and DNA that cause diseases in humans.
Hepatitis, Picornavirus, Togavirus, Paramyxovirus, HIV, Influenza, Ebola, Zika, HPV Adenovirus, Herpetoviridae, Rubella, etc.
Reference texts

Murray PR, et al; Medical Microbiology, Eighth edition, 2017, EDRA edition.
Educational objectives

The knowledge of:
cellular and molecular bases of viral pathogenicity,
of interactions between microorganism and host,
of the causes and mechanisms of onset of the main diseases of viral e
biotechnology applications in diagnosis, prophylaxis and antiviral chemotherapy.
Prerequisites

Knowledge of General Virology.
Teaching methods

Frontal lessons
Other information

Traineeship activities, Practical activities, tourism activities.
Learning verification modality

face to face
Extended program

General virology Viral replication,
Viral pathogenesis
Viral diagnosis, Picornavirus therapy, Polio.
Rhinovirus
orthomyxovirus orthomyxovirus
Ebola, Zika Paramyxovirus

HIV HIV
Togavirus, Rubella Herpesvirus
Herpesvirus Adenovirus
HAV HBV
HCV HPV

Cognomi M-Z

CFU
1
Teacher
Elio Cenci
Teachers
  • Elio Cenci
Hours
  • 12 ore - Elio Cenci
Language of instruction
Italian
Reference texts

Murray PR, Rosenthal KS, Pfaller MA. Microbiologia Medica, settima edizione, Edra Masson

Sherris Microbiologia Medica, 2012, EMSI Editore
Educational objectives

To provide the Medicine and Surgery Degree students the knowledge of Microbiology
able to guarantee the skills and competences required to achieve the essential levels of professional service.
The knowledge of the principal viruses responsible of infection, their pathogenicity mechanisms, host-parasite interaction, clinical presentation and diagnosis of the principal viral infections.
Teaching methods

Face to face lessons
Learning verification modality

Oral examination
Extended program

General virology

RNA Virus
Picornaviridae (Polio, Rhino, Coxsackievirus)
Orthomyxovirus
Paramyxovirus (Mumps, Measles, virus parainfluenza, RSV, hMPV)
Reovirus (Rotavirus)
Filovirus
Togaviridae
Arenavirus
Coronavirus
Calicivirus
Rhabdovirus
HIV
Hepatitis A, C, D, E

DNA Virus
HBV
Adenovirus
Herpesvirus (tipo 1, 2, 3, 4, 5, 6, 7, 8)
Papovavirus
Poxvirus
Parvovirus

MICROBIOLOGY - MOD. 4

Code GP005795
Location PERUGIA
CFU 1
Learning activities Caratterizzante
Area Formazione clinica interdisciplinare e medicina basata sulle evidenze
Academic discipline MED/07
Type of study-unit Obbligatorio (Required)

Cognomi A-L

CFU
1
Teacher
Stefano Perito
Teachers
  • Stefano Perito
Hours
  • 12 ore - Stefano Perito
Language of instruction

Italian language
Contents

General and Special Mycology. general characteristics of fungi, structure, reproduction, virulence factors, immune responses to fungi, Antimycotic, diagnosis of fungal cutaneous, superficial, subcutaneous, systemic, deep and opportunistic infections
Reference texts

Murray PR, et al. Medical Microbiology, Eighth edition, 2017, EDRA edition.
Educational objectives

The knowledge of:
cellular and molecular bases of fungal pathogenicity,
of interactions between microorganism and host,
the causes and mechanisms of onset of the main fungal diseases,
biotechnology applications in diagnosis, prophylaxis and anti-fungal chemotherapy.
Prerequisites

Knowledge of General Mycology, Immunology.
Teaching methods

Frontal lessons
Other information

Practical exercises, Internship activities, Tutorial activities.
Learning verification modality

Oral examen
Extended program

General Mycology Surface mycoses
Cutaneous skin infections.
Subcutaneous mycosis. Opportunistic mycosis
Aspergillus fumigatus
Cryptococcus
Pneumocystis Candida albicans

Cognomi M-Z

CFU
1
Teacher
Elio Cenci
Teachers
  • Elio Cenci
Hours
  • 12 ore - Elio Cenci
Language of instruction
Italian
Reference texts

Murray PR, Rosenthal KS, Pfaller MA. Microbiologia Medica, settima edizione, Edra Masson

Sherris Microbiologia Medica, 2012, EMSI Editore
Educational objectives

To provide the Medicine and Surgery Degree students the knowledge of Microbiology
able to guarantee the skills and competences required to achieve the essential levels of professional service.
General mycology: the fungal cell, replication and virulence fators of fungi; yeasts, molds, and dimorphic fungi. Diseases caused by fungi: superficial, cutaneous, subcutaneous, systemic, and opportunistic infections. Malassezia furfur, dermatophites (Microsporum spp, Trichophiton spp,, Epidermophiton); Histoplasma, Coccidioides, Paracocidioides, Blastomyces. Candida, Aspergillus, Cryptococcus. Diagnosis of fungal infections. Antimycotic drugs.
Teaching methods

Face to face lessons
Learning verification modality

Oral examination
Extended program

General mycology

Malassezia furfur; Microsporum spp, Trichophiton spp,, Epidermophiton; Histoplasma, Coccidioides, Paracocidioides, Blastomyces). Candida, Aspergillus., Cryptococcus.

MICROBIOLOGY - MOD. 5

Code GP005796
Location PERUGIA
CFU 1
Learning activities Caratterizzante
Area Formazione clinica interdisciplinare e medicina basata sulle evidenze
Academic discipline MED/07
Type of study-unit Obbligatorio (Required)

Cognomi A-L

CFU
1
Teacher
Stefano Perito
Teachers
  • Stefano Perito
Hours
  • 12 ore - Stefano Perito
Language of instruction

Italian language
Contents

General parasitology, biological cycles, vectors, parasitism, metabolism, nucleus, cytoplasm, pathogenesis, epidemiology, main protozoa, hints on helminths (Enterobius vermicularis).
Reference texts

Murray PR. et al, Medical Microbiology, 8th edition 2017, EDRA publisher.
Educational objectives

The knowledge of:
cellular and molecular bases of microbial pathogenicity,
of interactions between microorganism and host,
of the causes and mechanisms of onset of the main diseases of parasitic etiology
biotechnology applications in diagnosis, prophylaxis and antiparasitic chemotherapy.
Prerequisites

Basic knowledge of Biology and Immunology
Teaching methods

Frontal lessons
Other information

Practical exercises, training activities and tutoring activities.
Learning verification modality

Oral examen
Extended program

General parasitology
General parasitology
Toxoplasmosis Malaria
Malaria intestinal protozoa
Trichomonas intestinal protozoa
Enterobius

Cognomi M-Z

CFU
1
Teacher
Elio Cenci
Teachers
  • Elio Cenci
Hours
  • 12 ore - Elio Cenci
Language of instruction
italian
Reference texts

Murray PR, Rosenthal KS, Pfaller MA. Microbiologia Medica, settima edizione, Edra Masson

Sherris Microbiologia Medica, 2012, EMSI Editore
Educational objectives

To provide the Medicine and Surgery Degree students the knowledge of Microbiology
able to guarantee the skills and competences required to achieve the essential levels of professional service.
The knowledge of the structural and functional characteristics of the most relevant parasites responsible of diseases in man, and the clinical and diagnostic approaches to parasitic infections.
Teaching methods

Face to face lessons
Learning verification modality

Oral examination
Extended program

General Parasitology:

Plasmodium, Giardia, Trichomonas, Toxoplasma, Leishmania, Trypanosoma; Cestodes; Trematodes; Nematodes(Enterobius, Ascaris)

PROFESSIONALISING TRAINING IN MICROBIOLOGY

Code GP005797
Location PERUGIA
CFU 1
Learning activities Altro
Area Tirocini formativi e di orientamento
Academic discipline MED/07
Type of study-unit Obbligatorio (Required)

Cognomi A-L

CFU
1
Teacher
Stefano Perito
Teachers
  • Stefano Perito
Hours
  • 25 ore - Stefano Perito
Language of instruction

Italian language
Contents

Traineeship activities at the outpatient clinic, of the complex structure of Microbiology.
Reference texts

Murray P et al. Medical Microbiology. 0th edition 2017, EDRA.
Educational objectives

Patient medical history, active presence during biological samples collection, in external and internal patients at the Perugia hospital.
Prerequisites

Basic knowledge, discretion, confidentiality, knowledge of PPE.
Teaching methods

Practical activities, professional training activities
Other information

The student will find useful, knowledge of the symptoms and clinical signs of a patient.
will participate in the collection of biological samples.
Learning verification modality

Final assessment of the learning will be done online and sent to the secretariat of the Department of Medicine.
Extended program

Prescription and execution and start-up of biological samples for the diagnosis of the main biological samples. record the patient's medical history, interpret the results of the antibiogram, assist in the taking of samples of various biological samples (vaginal, urethral, tonsillary, pharyngeal, tonsillary, nasal, skin scales, blood sampling, reading results, interpret the main serodiagnosis.

Cognomi M-Z

CFU
1
Teacher
Elio Cenci
Teachers
  • Elio Cenci
Hours
  • 25 ore - Elio Cenci
Language of instruction
Italian
Reference texts
Murray PR, Rosenthal KS, Pfaller MA. Microbiologia Medica, ottava edizione, Edra Masson

Sherris Microbiologia Medica, 2012, EMSI Editore
Educational objectives
Provide students of the Degree in Medicine Surgery with the opportunity to attend the Clinical Microbiology Laboratory for a practical in-depth study of the knowledge of the discipline.
The knowledge of the general principles and the skill to obtain biologic samples for microbiologic analysis.
Teaching methods
Internship at external clinics of the Complex Microbiology Structure (groups of 4 students)

Theoretical and practical exercises in the laboratory of the Complex Microbiology Structure. Students will be divided into groups (8 per group), the duration of each exercise will be two hours.
Learning verification modality
oral examination
Extended program
Frequency in outpatient clinics for external users. Learning of sampling techniques of biological samples including the conjunctival, pharyngeal, auricular, urethral, vaginal, cervical, rectal, wound swab, blood samples.

Attendance at the laboratories of the S.C. of Microbiology. Learning and execution of the main methods of isolation, identification of bacteria, viruses, fungi, parasites. Evaluation of susceptibility testing to antibiotics
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