Unit ANATOMICAL PATHOLOGY
- Course
- Medicine and surgery
- Study-unit Code
- GP004638
- Location
- PERUGIA
- Curriculum
- In all curricula
- Teacher
- Angelo Sidoni
- CFU
- 13
- Course Regulation
- Coorte 2015
- Offered
- 2018/19
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa integrata
ANATOMICAL PATHOLOGY - MOD. 1
Code | GP004653 |
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Location | PERUGIA |
CFU | 4 |
Teacher | Angelo Sidoni |
Teachers |
|
Hours |
|
Learning activities | Caratterizzante |
Area | Discipline anatomo-patologiche e correlazioni anatomo-cliniche |
Academic discipline | MED/08 |
Type of study-unit | Obbligatorio (Required) |
Language of instruction | Italian |
Contents | Knowledge of the main pathological pictures (macroscopic and microscopic) of the human organs with clinical corrrelations. |
Reference texts | Robbins & Cotran: Pathologic Basis of Disease, last edition available, Elsevier |
Educational objectives | TRAINING AIMS: At the end of the course the student shall be conscious of the contribution provided by Pathological Anatomy to the phisicyan's decisional process, and must be able to use rationally the information derived from histocytopathologic diagnosis in order to perform the best prevention, diagnosis, prognosis and treatment of diseases. To reach these targets the student: 1) must demonstrate a good knowledge about gross and histological features of the main human diseases, and must be able to identify them by etiopathogenetic, physiopathologic, clinic, nosographic and epidemiologic points of view. 2) must know the most important methods used by Pathologist in his work, so that he can suitably manage the materials assigned to histological and cytological exams. The student must also correctly understand histological and cytological diagnosis and be conscious about the collaboration that must exists between the phisicyan and the pathologist. |
Prerequisites | In-depth knowledge of anatomy, histology, physiology and general pathology. |
Teaching methods | Lessons face to face (compulsory), practical training, seminars. |
Other information | DIDACTIC ORGANIZATION: The Pathological Anatomy teaching is carried out during the 4th year (1st and 2nd semester) of the course. The overall credits assigned to Pathological Anatomy are 14. The total amount of hours dedicated to lectures (ex cathedra) is 100. TEACHERS: Prof. Angelo Sidoni (coordinator) Dr. Guido Bellezza Dr. Rachele Del Sordo |
Learning verification modality | ORAL EXAM At the end of the second semester of the teaching the students who will have achieved the frequency attestation and who will be in rule with propedeutic exams will be admitted to support the Pathologic Anatomy exam after telematical booking . See web site http://www.med.unipg.it/ccl/ The commission, made up of two members, raises three questions regarding the program. The test, lasting not less than thirty minutes, beginning with the signing of the report. In case of unsatisfactory outcome the student has the right to renounce the continuation of the examination. The final grade is decided collegially as the average grades obtained in individual questions and after appropriate discussion. |
Extended program | CORE CURRICULUM (first semester) General section 1) History of Pathological Anatomy 2) Purposes of the autopsy 3) What is an epycrisis 4) The anatomic-clinical method 5) Biopsies and cytological specimens (collection modality, preservation, fixation, samples forwarding) 6) Intraoperative consultation. CARDIOVASCULAR SYSTEM Arteries Atherosclerosis Sistemic necrotizing vasculitis: group of Polyarteritis Nodosa Hypersensitivity vasculitis Granulomatous vasculitis (giant cells vasculitis) Giant cells arteritis Takayasu's arteritis Atherosclerotic aneurysms Aortitis and syphilitic aneurysms Cystic medial necrosis and related , dissecting aneurysms Veins Venous varix Thrombophlebitis and phlebothrombosis Lymphatic vessels Lymphedema Heart Congestive heart failure Left ventricular failure Right ventricular failure Ischemic cardiopathy Angina pectoris Sudden cardiac death Acute myocardial infarction Chronic ischemic cardiopathy Hypertensive cardiopathy Rheumatic carditis Congenital cardiopathies Ventricular septum defects Atrial septum defects Patent ductus arteriosus Aortic coarctation Fallot's tetralogy Cor pulmonale Myocardiopathies Myocarditis Valvular heart diseases Aortic calcific stenosis Mitralic ring calcification Mitral valve prolapse (floppy valve syndrome, Barlow's syndrome) Endocardium diseases Nonbacterial thrombotic endocarditis (marantic endocarditis) Nonbacterial verrucous endocarditis (Libman-Sacks' disease) Carcinoid syndrome Endomyocardial fibroelastosis Pericarditis and pericardial effusions RESPIRATORY SYSTEM Pulmonary embolism, infarct and hemorrhage Acute respiratory distress syndrome (ARDS) Newborn's respiratory failure (hyaline membrane disease) Atelectasy Sudden infant death syndrome (SIDS) Chronic obstructive pulmonary disease (COPD) Chronic bronchitis (included small airways disease) Emphysema Bronchial asthma Bronchiectasy Pneumoconiosis (general aspects) Pulmonary infections Lobar pneumonia Lobular pneumonia Lung abscess Viral and mycoplasma pneumonias (atypical pneumonia) Primary tuberculosis Post-primary tuberculosis (re-activation, secondary disease) Tumors of lung CarcinomasNeuroendocrine tumorsMetastatic pulmonary tumors Mesothelioma Disorders of pleura Pleural effusions and pleuritis Hemothorax Chylothorax Pneumothorax Illustration of pertinent clinico-pathological cases. PROFESSIONAL TRAINING Pathologic activity in the hospital: Divided in small groups and guided by a tutor, the students will visit the "Struttura Complessa di Anatomia e Istologia Patologica" and will take vision of all the activities carried out. Particular attention will be given to the compilation requests for cytologic and histopathologic exams, to the right forward of biological samples and to the fixation of specimens. Autopsy demonstration: The autopsy is a very important medical act, both under formative and clinical points of view. The availability of autopsies depends on clinical units doctors' requests, therefore we can't preventively plan them. Students are invited to attend all available autopsies. During the autopsy the pathologist will interactively show the pathological findings, the relative diagnosis and the relationships between them and the signs and symptoms presented by patient in life. In consideration of the deficiency of autopsies the demonstrative activity will be carried out also through archive and/or informatic support cases. ELECTIVE DIDACTIC ACTIVITIES (ADE) Exercitations for small groups of students with microscopic demonstrations of cytological and histological specimens of the principal human diseases. Attendance to the weekly scientific meetings of the Pathological Anatomy Institute. Continuous frequency for preparation of degree thesis. |
ANATOMICAL PATHOLOGY - MOD. 2
Code | GP004654 |
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Location | PERUGIA |
CFU | 4 |
Teacher | Angelo Sidoni |
Teachers |
|
Hours |
|
Learning activities | Caratterizzante |
Area | Discipline anatomo-patologiche e correlazioni anatomo-cliniche |
Academic discipline | MED/08 |
Type of study-unit | Obbligatorio (Required) |
Language of instruction | Italian |
Contents | Please see the Mod.1 |
Reference texts | Please see the Mod.1 |
Educational objectives | Please see the Mod.1 |
Prerequisites | Please see the Mod.1 |
Teaching methods | Please see the Mod.1 |
Other information | Please see the Mod.1 |
Learning verification modality | Please see the Mod.1 |
Extended program | DISORDERS OF IMMUNE SYSTEM Reumathoid arthritis SLE Sjögen's syndrome AIDS DISORDERS OF URINARY TRACT Renal failure (uremic syndrome) Glomerulopathies Clinical features of glomerulopathies Pathogenesis of glomerular injury Circulating immune-complexes nephritis In situ immune-complexes nephritis Nephrotic syndrome Minimal change disease (lipoid nephrosis) Membranous glomerulopathy (membranous nephrosis) Focal-segmental glomerulosclerosis Membranoproliferative glomerulonephritis Nephritic syndrome Diffuse proliferative glomerulonephritis Rapidly progressive glomerulonephritis (crescentic) IgA nephropathy (Berger's disease) Tubulointerstitial diseases Tubulointerstitial nephritis Acute pyelonephritis Chronic pyelonephritis and reflux nephropathy Acute tubular necrosis Vascular diseases of kidney Secondary hypertensive vascular disease Idiopatic hypertensive vascular disease Malignant hypertension - malignant nephrosclerosis Benign nephrosclerosis Cystic renal diseases Isolated cysts Polycystic kidney disease Urinary tract obstruction Calculi Hydronephrosis Neoplastic disease Renal clear cell carcinoma Wilms' tumor Carcinoma of urinary tract (calyx, pelvis, ureter, urethra) DIGESTIVE SYSTEM Oral cavity Precancerous lesions and oral cavity carcinoma Tumors of salivary glands Esophagus Atresia Achalasia Diverticula Webs and rings Hiatal Hernia Esophagitis Esophageal varix Mucosal tear (Mallory-Weiss syndrome) Esophageal carcinoma Stomach Pyloric stenosis Gastritis Acute gastritis Chronic gastritis Hypertrophic gastritis (Menetrier's disease) Acute stress ulcer disease Peptic ulcer disease Gastric polyps Gastric cancer Gastric lymphomas GIST Small bowel Diverticula Ischemic bowel disease Transmural infarction Mucosal-intramural infarction Crohn's disease (local enteritis) Disorders of absorption Celiac disease (non-tropical sprue, gluten-sensitive enteropathy) Whipple's disease Tumors Adenocarcinoma Neuroendocrine tumor Lymphoma Idiopathic ulcerative colitis Neoplastic diseases Polyps Hyperplastic polyps Tubular (pedunculated) adenomas Tubulo-villous adenomas Villous adenomas Adenoma-carcinoma multistep cancerogenesis model Polyposis of colon Familial polyposis of colon Gardner's syndrome Turcot's syndrome Peutz-Jeghers' syndrome Colorectal carcinoma Appendices Mucocele and pseudomyxoma peritonei SKIN Basal cell carcinoma Squamous cell carcinoma Nevi and melanoma HEMATOPOIETIC AND LYMPHOID SYSTEM Specific and non-specific adenopathies Non-Hodgkin lymphomas Hodgkin lymphoma Myeloma Splenomegaly LIVER AND BILIARY TRACT Jaundice Hepatic failure Vascular diseases Steatosis Reye's syndrome Cholangitis and liver abscesses Viral hepatitis Chronic hepatitis Massive and sub-massive hepatic necrosis Hepatic cirrhosis Portal Hypertension Alcoholic liver disease and cirrhosis Post-necrotic, post-hepatitic cirrhosis Biliary cirrhosis Hemochromatosic cirrhosis Wilson's disease, alpha-1-antitrypsin deficit Hepatocarcinoma Colangiocarcinoma Gallstones disease Cholecystitis Tumors of gallbladder, cholangiocarcinomas, Vater's papilla carcinoma PANCREAS Acute and chronic pancreatitis Carcinoma MALE REPRODUCTIVE SYSTEM Testis and epidydimis Tumors Prostate Prostatic hyperplastic nodular disease Carcinoma FEMALE REPRODUCTIVE SYSTEM Uterine cervix Cervicitis Polyps Pre-cancerous lesions Carcinoma Uterus and endometrium Endometriosis and adenomyosis Dysfunctional uterine bleedings Endometrial hyperplasia Tumors Leiomyoma and leiomyosarcoma Endometrial carcinoma Ovary Tumors Common epithelial tumors Serous tumors Mucinous tumors Endometroid tumors Clear cells tumors Brenner's tumor Germ cells tumors Teratoma Dysgerminoma Yolk sac tumor Chorioncarcinoma Stromal tumors Granulosa cells tumors Fibroma-thecoma-luteoma Sertoli-Leydig cells tumors Clinical features in ovarian neoplasms Metastatic ovarian tumors Gestational trophoblastic diseases Hydatiform mole Invasive mole Chorioncarcinoma BREAST Fibrocystic lesions Sclerosing adenosis Epithelial hyperplasia Relations between fibrocystic lesions and carcinoma Thraumatic fat necrosis Tumors Fibroadenoma, phyllodes tumor Papilloma and papillary carcinoma Carcinoma Diagnostic procedures in breast cancer Prognostic factors in breast cancer Pathology of male breast Gynecomastia Carcinoma Tyroid Thyroidites Hashimoto's thyroiditis De Quervain's subacute thyroiditis Riedel's thyroiditis Diffuse (non-toxic) and multinodular goiters Hyperthyroidism Graves-Flaiani-basedow's disease (toxic goiter) Adenomas Carcinomas Thyroglossal duct cysts Adrenal glands Hypo- and hyperfunction of adrenal glands Tumors Endocrine pancreas Pathologic anatomy in diabetes mellitus NERVOUS SYSTEM Frequent pathophysiologic complications Intracranial hypertension and hernations Intracranial edema Hydrocephalus Infections Meningitis Pyogenic meningitis Lymphocytic meningitis Chronic meningitis Brain abscesses Vascular diseases Hischemic encephalopathy Ischemic stroke Non-thraumatic cerebral hemorrage Intraparenchymal hemorrage Subarachnoid hemorrage Mixed intraparenchymal and subarachnoid hemorrage Epidural hematoma Subdural hematoma Demyelinative disease Multiple sclerosis Tumors of central nervous system W.H.O. classification Metastatic tumors |
ANATOMICAL PATHOLOGY - MOD. 3
Code | GP004655 |
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Location | PERUGIA |
CFU | 2 |
Teacher | Angelo Sidoni |
Teachers |
|
Hours |
|
Learning activities | Caratterizzante |
Area | Medicina di laboratorio e diagnostica integrata |
Academic discipline | MED/08 |
Type of study-unit | Obbligatorio (Required) |
Language of instruction | Italian |
Contents | Please see MOD.1 |
Reference texts | Please see MOD.1 |
Educational objectives | Please see MOD.1 |
Prerequisites | Please see MOD.1 |
Teaching methods | Please see MOD.1 |
Other information | Please see MOD.1 |
Learning verification modality | Please see MOD.1 |
Extended program | Please see MOD.1 |
ANATOMICAL PATHOLOGY - MOD. 4
Code | GP004656 |
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Location | PERUGIA |
CFU | 1 |
Teacher | Guido Bellezza |
Teachers |
|
Hours |
|
Learning activities | Caratterizzante |
Area | Medicina di laboratorio e diagnostica integrata |
Academic discipline | MED/08 |
Type of study-unit | Obbligatorio (Required) |
Language of instruction | Italian |
Contents | Main human pathological diseases of central nervous system and oral cavity. |
Reference texts | V. Kumar, A.K. Abbas, N. Fausto, J.C. Aster Le basi patologiche delle malattie, Elsevier, VIII ed, 2010 |
Educational objectives | The main goal of education is to provide students with the foundation for dealing with the study of central nervous system and oral cavity diseases. Particular attention will be given in this regard to the aspects of the differential diagnosis between various injuries clinically evident. At the end of the course the student will be able to correlate the pathological aspects with those clinical and formulate hypotheses to propose all'anatomo differential diagnostic pathologist through biopsies and cytological . |
Prerequisites | In order to understand and know how to apply the most important human diseases and pathological aspects of the same with the anatomical and clinical correlations necessary, the student must have basic knowledge of Anatomy, Histology, Biology, physiology and general pathology |
Teaching methods | face-to-face Participation in autopsies. Demonstration of surgical specimens |
Learning verification modality | Oral examination |
Extended program | Intracranial hemorrhage: intraparenchymal, subaracnoid and epidural hematoma. Cerebral infarction. Meningitis. Cerebral Tumors. Oral cavity disease |
PROFESSIONALISING TRAINING IN ANATOMICAL PATHOLOGY
Code | GP005689 |
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Location | PERUGIA |
CFU | 2 |
Teacher | Angelo Sidoni |
Teachers |
|
Hours |
|
Learning activities | Altro |
Area | Tirocini formativi e di orientamento |
Academic discipline | MED/08 |
Type of study-unit | Obbligatorio (Required) |
Language of instruction | Italian |
Contents | See the information in the sheet GP005555 - PROFESSIONAL TRAINING IN PATHOLOGICAL ANATOMY |
Reference texts | See the information in the sheet GP005555 - PROFESSIONAL TRAINING IN PATHOLOGICAL ANATOMY |
Educational objectives | See the information in the sheet GP005555 - PROFESSIONAL TRAINING IN PATHOLOGICAL ANATOMY |
Prerequisites | See the information in the sheet GP005555 - PROFESSIONAL TRAINING IN PATHOLOGICAL ANATOMY |
Teaching methods | See the information in the sheet GP005555 - PROFESSIONAL TRAINING IN PATHOLOGICAL ANATOMY |
Other information | See the information in the sheet GP005555 - PROFESSIONAL TRAINING IN PATHOLOGICAL ANATOMY |
Learning verification modality | See the information in the sheet GP005555 - PROFESSIONAL TRAINING IN PATHOLOGICAL ANATOMY |
Extended program | See the information in the sheet GP005555 - PROFESSIONAL TRAINING IN PATHOLOGICAL ANATOMY |