Unit FOOD BIOCHEMISTRY
- Course
- Economics and culture of human nutrition
- Study-unit Code
- A001470
- Curriculum
- In all curricula
- Teacher
- Carlo Alberto Palmerini
- Teachers
-
- Carlo Alberto Palmerini
- Hours
- 54 ore - Carlo Alberto Palmerini
- CFU
- 6
- Course Regulation
- Coorte 2021
- Offered
- 2022/23
- Learning activities
- Base
- Area
- Discipline biologiche
- Academic discipline
- BIO/10
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa monodisciplinare
- Language of instruction
- ITALIAN
- Contents
- Amino acids. Proteins. Hemoglobin. Enzymes. Nucleic acids.
Carbohydrates. Triacylglycerors. Phospolipids. Cholesterol. Membranes.
Glycolysis. Oxidatin of Fatty acids. Catabolism of protein. Urea Cycle. The
citric acid cycle. Oxidative phosphorylation - Reference texts
- Lehninger Principles of Biochemistry; Biochemistry- Streyer Zanichelli
- Educational objectives
- Teaching is the first teaching of Biochemistry and examines the
macromolecules of the cell, the main nutrients and their impact on the
energy cell metabolism.
The main goal of education is to provide students with the bases to
address the study of macromolecules in the cells of animals and plants
with particular reference to the relationship between structure and
function; of metabolic pathways and their interconnections.
The main knowledge gained will be:
-knowledge of the macromolecules present in the cells;
-the characteristics of the enzyme kinetics;
-knowledge base for studying the reactions that occur in the cell,
following the rules by the reactions in terms of energy, reaction rate,
temperature and pH;
-fondamentali tools and methodologies for the individual macromolecules
in the cells. Experimental approach to investigate the complex
macromolecular structures.
The main skills are:
-identification of cell markers of the state in physiological and
pathological conditions;
-to identify the molecules involved in cell metabolism;
-assess transcription and translation in the genetic information;
-assess the kinetic parameters in the enzymatic activities. - Prerequisites
- In order to understand the course content, you must have successfully
supported the examination of Chemistry.
In addition, other topics require knowledge of physics, organic chemistry
and elements of Mathematics. These skills are a prerequisite for the
student who wants to follow the course with profit. - Teaching methods
- The course is organized as follows:
-lezione classroom on all the topics of the course;
-esercitazioni at the computer lab for simulation of enzymatic activities
and determine the main kinetic parameters. - Learning verification modality
- The exam includes an oral examination. The oral exam in a discussion
lasting about 40min aimed at ascertaining the level of knowledge and
understanding achieved by students on the theoretical and
methodological implications mentioned in the program. The oral exam
will also test the ability of communication with the student of language
and autonomous organization of the exhibition on the same topics in
theoretical content. - Extended program
- Eukariotic and prokariotic cells. Virus. Amino acids chemical properties.
Peptide bonds. Proteins: structure and properties. Myoglobin and
Hemoglobin. Collagen, Keratin. Enzymes: Kinetyics, Mechanisms of
action, Regulation of activities. Inhibition. Coenzymes. Nucleic acid
stucture and function. Bases. Nucleosides and nucleotides.
Carbohydrates: monosaccharides, disaccharides, polysaccharides and
structural functions. Lipids: phospholipids, neutral lipids, cholesterol. Bile
acids. Steroid hormones. Membranes: stucture, assembly and function.
Metabolism. ADP/ATP cycle. Biologic oxidation. Catabolism of
carbohydrates: glycolysis, gluconeogenesis, glycogenogenesis.The citric
acid cycle. The catabolism of acetyl-CoA. Oxidation of fatty acids:
ketogenesis. Catabolism of proteins and amino acid nitrogen.
Transamination and ossidative deamination. Urea biosynthesis.
Catabolism of the carbon skeletrons of amino acids. Oxidative
phosphorylation and mitocondrial transport systems.