Unit MICROBIOLOGY

MICROBIOLOGY - MOD. 1

Code	GP005915
Location	TERNI
CFU	2
Teacher	Stefano Perito
Teachers	Stefano Perito
Hours	24 ore - Stefano Perito
Learning activities	Caratterizzante
Area	Patologia generale e molecolare, immunopatologia, fisiopatologia generale, microbiologia e parassitologia
Academic discipline	MED/07
Type of study-unit	Obbligatorio (Required)
Language of instruction	teaching in Italian
Contents	General microbiologist, Medical Parasitology
Reference texts	Murray PR, Medical Microbiology, 8th edition, Elsevier edz.
Educational objectives	The knowledge of: cellular and molecular bases of microbial pathogenicity, of interactions between microorganism and host, the causes and mechanisms of onset of the main diseases of bacterial, fungal, viral and parasitic etiology biotechnology applications in diagnosis, prophylaxis and antimicrobial chemotherapy.
Prerequisites	Knowledge of Biology, Anatomy, Immunology
Teaching methods	Frontal lessons
Other information	Outpatient activity at the clinics of the complex structure of Microbiology, practical exercises
Learning verification modality	Oral examen, face to face
Extended program	Presentation of the course, Differences between prokaryotes / eukaryotes Gram + cell wall Gram-cell wall, Optional facilities Metabolism, Nutrition, Growth curve Culture media for bacteria Genetics of bacteria. Genetic exchange between bacteria. Contagion and transmission of microorganisms Bacterial pathogenesis Bacterial pathogenesis Vaccines, Antibiotic Serums Antibiogram, Sterilization, Disinfection. General parasitology Toxoplasmosis Malaria Malaria intestinal protozoa Trichomonas intestinal protozoa Enterobius

MICROBIOLOGY - MOD. 2

Code	GP005916
Location	TERNI
CFU	1
Teacher	Lucia Pitzurra
Teachers	Lucia Pitzurra
Hours	12 ore - Lucia Pitzurra
Learning activities	Caratterizzante
Area	Patologia generale e molecolare, immunopatologia, fisiopatologia generale, microbiologia e parassitologia
Academic discipline	MED/07
Type of study-unit	Obbligatorio (Required)
Language of instruction	Italian
Contents	Caratteristiche struttrali e funzionali dei miceti. Principali funghi patogeni responsabili di infezioni nell'uomo ( Candida spp, Cryptococcus spp, Aspegillus spp., dermatofiti, funghi dimorfi) Chemioterapici antimicotici ( caratteristiche, meccanismo d'azione, utilizzazione, meccanismi di resistenza) Metodi microbiologici, colturali e non colturali, utilizzati nella diagnosi di infezioni fungine.
Reference texts	Microbiologia Medica P.R. Murray, K.S. Rosenthal, M.A. Pfaller EDRA MASSON Ed.
Educational objectives	Most important groups of fungi and related disease
Prerequisites	The knowledge to understand the topics covered in the Course, and required to achieve the objectives of the discipline are: immunology - essential anatomy – important biology – useful
Teaching methods	lectures on all subject of the course
Learning verification modality	The oral examination will be focused on the knowledge of the different fungal pathogens in the framework of the host-parasite relationship.
Extended program	Essential characteristics of fungi known to infect humans. Most important groups of fungi and related diseases. Antifungal drugs ( Classification, mechanism of action and resistance, combined therapies) Coltural and non coltural microbial methods useful in the diagnosis of fungal infections.

MICROBIOLOGY - MOD. 3

Code	GP005917
Location	TERNI
CFU	1
Teacher	Antonella Mencacci
Teachers	Antonella Mencacci
Hours	12 ore - Antonella Mencacci
Learning activities	Caratterizzante
Area	Patologia generale e molecolare, immunopatologia, fisiopatologia generale, microbiologia e parassitologia
Academic discipline	MED/07
Type of study-unit	Obbligatorio (Required)
Language of instruction	Italian
Educational objectives	Knowledge of the major genera of bacteria resposible for disease in man and of the mechanisms of bacterial pathogegesis. Clinical manifestations and diagnosis of bacteral infectious diseases.

MICROBIOLOGY - MOD. 4

Code	GP005918
Location	TERNI
CFU	1
Teacher	Elio Cenci
Teachers	Elio Cenci
Hours	12 ore - Elio Cenci
Learning activities	Caratterizzante
Area	Formazione clinica interdisciplinare e medicina basata sulle evidenze
Academic discipline	MED/07
Type of study-unit	Obbligatorio (Required)
Language of instruction	italian
Reference texts	Murray PR, Rosenthal KS, Pfaller MA. Microbiologia Medica, settima edizione, Edra Masson Sherris Microbiologia Medica, 2012, EMSI Editore
Educational objectives	To provide the Medicine and Surgery Degree students the knowledge of Microbiology able to guarantee the skills and competences required to achieve the essential levels of professional service. General mycology: the fungal cell, replication and virulence fators of fungi; yeasts, molds, and dimorphic fungi. Diseases caused by fungi: superficial, cutaneous, subcutaneous, systemic, and opportunistic infections. Malassezia furfur, dermatophites (Microsporum spp, Trichophiton spp,, Epidermophiton); Histoplasma, Coccidioides, Paracocidioides, Blastomyces. Candida, Aspergillus, Cryptococcus. Diagnosis of fungal infections. Antimycotic drugs.
Teaching methods	face to face lessons
Learning verification modality	Oral eamination
Extended program	RNA Virus Picornaviridae (Polio, Rhino, Coxsackievirus) Orthomyxovirus Paramyxovirus (Measles, Mumps, virus parainfluenza, RSV, hMPV) Reovirus (Rotavirus) Filovirus Togaviridae Arenavirus Coronavirus Calicivirus Rhabdovirus HIV Hepatitis A, C, D, E DNA Virus HBV Adenovirus Herpesvirus (tipo 1, 2, 3, 4, 5, 6, 7, 8) Papovavirus Poxvirus Parvovirus

MICROBIOLOGY - MOD. 5

Code	GP005919
Location	TERNI
CFU	1
Teacher	Elio Cenci
Teachers	Elio Cenci
Hours	12 ore - Elio Cenci
Learning activities	Caratterizzante
Area	Formazione clinica interdisciplinare e medicina basata sulle evidenze
Academic discipline	MED/07
Type of study-unit	Obbligatorio (Required)
Language of instruction	Italian
Reference texts	Murray PR, Rosenthal KS, Pfaller MA. Microbiologia Medica, settima edizione, Edra Masson Sherris Microbiologia Medica, 2012, EMSI Editore
Educational objectives	To provide the Medicine and Surgery Degree students the knowledge of Microbiology able to guarantee the skills and competences required to achieve the essential levels of professional service. The knowledge of the structural and functional characteristics of the most relevant parasites responsible of diseases in man, and the clinical and diagnostic approaches to parasitic infections.
Teaching methods	Face to face lessons
Learning verification modality	Oral examination
Extended program	PARASSITOLOGIA GENERALE: Sistematica e nomenclatura zoologica; associazioni biologiche; generalità sui cicli di vita dei parassiti; specificità parassitaria; interazioni parassita-ospite e azione patogena dei parassiti; malattie parassitarie di importanza medica; lotta alle malattie parassitarie; sistematica dei parassiti umani. PARASSITOLOGIA SPECIALE: Protozoi parassiti dell'uomo (Plasmodium, Giardia, Trichomonas, Toxoplasma, Leishmania, Trypanosoma; Cestodi; Trematodi e Nematodi (Enterobius, Ascaris) parassiti dell' uomo. Artropodi parassiti e principali vettori di parassitosi umane.

PROFESSIONALISING TRAINING IN MICROBIOLOGY

Code	GP005920
Location	TERNI
CFU	1
Teacher	Elio Cenci
Teachers	Elio Cenci
Hours	25 ore - Elio Cenci
Learning activities	Altro
Area	Tirocini formativi e di orientamento
Academic discipline	MED/07
Type of study-unit	Obbligatorio (Required)
Language of instruction	Italian
Reference texts	Murray PR, Rosenthal KS, Pfaller MA. Microbiologia Medica, ottava edizione, Edra Masson Sherris Microbiologia Medica, 2012, EMSI Editore
Educational objectives	Provide students of the Degree in Medicine Surgery with the opportunity to attend the Clinical Microbiology Laboratory for a practical in-depth study of the knowledge of the discipline. The knowledge of the general principles and the skill to obtain biologic samples for microbiologic analysis.
Teaching methods	Internship at external clinics of the Complex Microbiology Structure (groups of 4 students) Theoretical and practical exercises in the laboratory of the Complex Microbiology Structure. Students will be divided into groups (8 per group), the duration of each exercise will be two hours.
Extended program	Frequency in outpatient clinics for external users. Learning of sampling techniques of biological samples including the conjunctival, pharyngeal, auricular, urethral, vaginal, cervical, rectal, wound swab, blood samples. Attendance at the laboratories of the S.C. of Microbiology. Learning and execution of the main methods of isolation, identification of bacteria, viruses, fungi, parasites. Evaluation of susceptibility testing to antibiotics.