Unit GENERAL BIOLOGY AND GENETICS
- Course
- Medicine and surgery
- Study-unit Code
- GP004728
- Location
- TERNI
- Curriculum
- In all curricula
- Teacher
- Maria Laura Belladonna
- CFU
- 7
- Course Regulation
- Coorte 2019
- Offered
- 2019/20
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa integrata
GENERAL BIOLOGY AND GENETICS - MOD. 1
Code | GP004753 |
---|---|
Location | TERNI |
CFU | 6 |
Teacher | Maria Laura Belladonna |
Teachers |
|
Hours |
|
Learning activities | Base |
Area | Discipline generali per la formazione del medico |
Academic discipline | BIO/13 |
Type of study-unit | Obbligatorio (Required) |
Language of instruction | Italian |
Contents | Cell organization of living organisms. Chemical components of the cell. Prokaryotic and eukaryotic cells. The eukaryotic cell components: cell membrane, mitochondria, endomembrane system, cytoskeleton and nucleus. Cell communication: membrane receptors and signal transduction. Cell adhesion mechanisms. DNA replication and cell cycle. Asexual and sexual reproduction. Transcription and protein synthesis. Regulation of gene expression. Tumor cells. |
Reference texts | Becker "IL MONDO DELLA CELLULA" Ed. Pearson – 9th edition Solomon et al. "FONDAMENTI DI BIOLOGIA" Ed. EdiSES – 7th edition |
Educational objectives | The main objective of the module is the integrated study of animal cell, with particular regard to mechanisms involved in the biogenesis of organels and cell structures, of cell-cell and cell-environment interactions, bioenergetics and transmission of genetic information. Students should acquire the ability to connect different cellular processes and apply the acquired knowledge to understand the following teachings. |
Prerequisites | To effectively follow and understand the topics covered in the course of General Biology and Genetics is necessary for the student to have a basic knowledge of Chemistry and Biology as it is normally acquired in high school. In particular, basic knowledge should be relative to cell structure, atom structure, chemical bonds, simple inorganic and organic molecules. |
Teaching methods | Face-to-face and practical training. |
Other information | For information on support services for students with disabilities and / or DSA visit the page http://www.unipg.it/disabilita-e-dsa |
Learning verification modality | The exam consists of a written and/or an oral exam. Written exam is a multiple choice test on all the topics covered in the course, lasting 60 minutes. The aim of the written exam is verifying the basic level of knowledge necessary to access to oral examination. The oral examination lasts not longer than 30 minutes and enables to verify the level of knowledge and understanding achieved by the student; the ability of the student to highlight the correlations between the various biological processes. In addition, the oral examination will assess the student's ability to communicate and expose with appropriate language the topics of the cell biology. The exam will be performed at the end of the course according to the exam timetable. The evaluation will be in thirtieths (minimum: 18/30; maximum: 30/30 cum laude) |
Extended program | Cell organization of living organisms. Chemical components of the cell: water and macromolecules (proteins, nucleic acids, polysaccharides and lipids). Prokaryotic and eukaryotic cells, viruses and prions. Bioenergetics. Enzymes. The eukaryotic cell components: cell membrane (composition and structure, permeability, ion and molecule transport); mitochondria and chemotrophic energy metabolism; endomembrane system (endoplasmic reticulum, Golgi apparatus, lysosome; vesicular transport, exocytosis and endocytosis); peroxisome. Cell communication: electric signals, chemical signals, membrane receptors and signal transduction. Eukaryotic cell components: Cytoskeleton (microtubules, microfilaments and intermediate filament), nucleus (chromatin, chromosomes, nucleolus). Cell adhesion mechanisms. Genetic information and gene expression. Genes and genome in prokaryotes and eukaryotes. DNA replication. Cell cycle phases and control. Apoptosis. Asexual and sexual reproduction. Meiosis. Gene recombination. Gametogenesis and fertilization. Karyotype. Gene, chromosome and genome mutations. Transcription. RNA maturation. Messenger RNA. Transfer RNA. Ribosomal RNA and ribosomes. Genetic code and translation of gene information: protein synthesis. Regulation of gene expression in prokaryotes: bacterial operon. Regulation of gene expression in eukaryotes at transcriptional and post-transcriptional level. Tumor cells. |
GENERAL BIOLOGY AND GENETICS - MOD. 2
Code | GP004754 |
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Location | TERNI |
CFU | 1 |
Teacher | Maria Laura Belladonna |
Teachers |
|
Hours |
|
Learning activities | Base |
Area | Discipline generali per la formazione del medico |
Academic discipline | BIO/13 |
Type of study-unit | Obbligatorio (Required) |
Language of instruction | Italian |
Contents | Principles of general and human genetics. |
Reference texts | Becker "IL MONDO DELLA CELLULA" Ed. Pearson – 9th edition Solomon et al. "FONDAMENTI DI BIOLOGIA" Ed. EdiSES – 7th edition |
Educational objectives | The main objective of the module is the integrated study of animal cell, with particular regard to transmission of genetic information, and principles of general and human genetics. Students should acquire the ability to connect different cellular processes and apply the acquired knowledge to understand the following teachings. |
Prerequisites | To effectively follow and understand the topics covered in the course of General Biology and Genetics is necessary for the student to have a basic knowledge of Chemistry and Biology as it is normally acquired in high school. In particular, basic knowledge should be relative to cell structure, atom structure, chemical bonds, simple inorganic and organic molecules. |
Teaching methods | Face-to-face and practical training |
Other information | For information on support services for students with disabilities and / or DSA visit the page http://www.unipg.it/disabilita-e-dsa |
Learning verification modality | The exam consists of a written and/or an oral exam. Written exam is a multiple choice test on all the topics covered in the course, lasting 60 minutes. The aim of the written exam is verifying the basic level of knowledge necessary to access to oral examination. The oral examination lasts not longer than 30 minutes and enables to verify the level of knowledge and understanding achieved by the student; the ability of the student to highlight the correlations between the various biological processes. In addition, the oral examination will assess the student's ability to communicate and expose with appropriate language the topics of the cell biology. The exam will be performed at the end of the course according to the exam timetable. The evaluation will be in thirtieths (minimum: 18/30; maximum: 30/30 cum laude) |
Extended program | Principles of general and human genetics. Mendel's Laws. Incomplete dominance and codominance. Multiple alleles. Pleiotropy. Gene interaction. Quantitative traits. Continuous and discontinuous variation. Normal and pathologic human karyotypes. Mendel's inheritance in humans. Genetic pedigrees (Family trees). Dominant and recessive autosomal heredity, sex linkage. |