Unit GENERAL PHARMACOLOGY
- Course
- Biotechnology
- Study-unit Code
- 55058306
- Curriculum
- In all curricula
- Teacher
- Maria Teresa Pallotta
- Teachers
-
- Maria Teresa Pallotta
- Hours
- 42 ore - Maria Teresa Pallotta
- CFU
- 6
- Course Regulation
- Coorte 2021
- Offered
- 2023/24
- Learning activities
- Affine/integrativa
- Area
- Attività formative affini o integrative
- Academic discipline
- BIO/14
- Type of study-unit
- Opzionale (Optional)
- Type of learning activities
- Attività formativa monodisciplinare
- Language of instruction
- Italian
- Contents
- Pharmacokinetics: the dynamic of drug absortion, distribution, metabolism and elimination. Routes of administration
Pharmacodynamics
- Molecular drug targets
- Families of receptors and signaling pathways
- Quantitation of drug-receptor interaction and effects, radioligand binding method, molecular characterization (ion channels, G-protein-coupled receptor, receptor protein kinases, intracellular receptors).
- Transcription factors.
- Agonist and antagonist ligands
- Regulation of receptors
- Pharmacogenomics and pharmacogenetics
- Pharmacology of biotechnologic drugs - Reference texts
- Paoletti, Nicosia, Clementi, Fumagalli "Farmacologia generale e molecolare" UTET
- Educational objectives
- Biotechnologic competence - Knowledge and comprehension of the production, analysis and control of drugs obtained by means of
biotechnologic processes; general principles of pharmacology in relationship to the project of drugs and in general of bioactive molecules
obtained by means of biotechnologic processes; structura and biologic properties of animal and plant cells and tissues. - Prerequisites
- Having passed the exams of Physiology and Biochemistry
- Teaching methods
- Face-to-face theoretical lessons
- Other information
- Students with disabilities and/or DSA are invited to visit the page dedicated to the tools and measures envisaged and to agree in advance what is necessary with the teacher (https://www.unipg.it/disabilita-e -dsa)
- Learning verification modality
- Oral exam, aimed at determining knowledge of both pharmacokinetics and pharmacodynamics, which are the fundamental elements for the correct use and design of a drug
- Extended program
- Introduction to pharmacology.
Concept of drug and medication.
Chemical and physical properties of drugs.
Pharmacokinetics: the dynamic of drug absortion, distribution, metabolism and elimination. Routes of administration
Pharmacodynamics
- Molecular drug targets
- Families of receptors and signaling pathways
- Quantitation of drug-receptor interaction and effects, radioligand binding method, molecular characterization (ion channels, G-protein-coupled receptor, receptor protein kinases, intracellular receptors).
- Transcription factors.
- Agonist and antagonist ligands
- Regulation of receptors
- Pharmacogenomics and pharmacogenetics
- Pharmacology of biotechnologic drugs