Unit LABORATORY MEDICINE
- Course
- Medicine and surgery
- Study-unit Code
- GP005676
- Curriculum
- In all curricula
- CFU
- 8
- Course Regulation
- Coorte 2021
- Offered
- 2023/24
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa integrata
CLINICAL BIOCHEMISTRY
| Code | A001682 |
|---|---|
| CFU | 2 |
| Learning activities | Caratterizzante |
| Area | Medicina di laboratorio e diagnostica integrata |
| Academic discipline | BIO/12 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 2
- Teacher
- Paolo Gorello
- Teachers
- Paolo Gorello
- Hours
- 25 ore - Paolo Gorello
- Language of instruction
- Italian
- Contents
- - Generation of laboratory data and its critical interpretation.- Reliability of test results: precision, accuracy, sensitivity, specificity.- Quality management, predictive value and decision-making levels.- Units of measurement in Clinical Biochemistry, sources of preanalytical variability, reference values, Biological variability.- Principles and techniques for collecting, processing and storage of biological samples.- Methods used in Clinical Biochemistry:Centrifugation techniques, UV-Visible spectrophotometry and Spectrofluorimetry- Point-of-Care testing, Chemical dry state.- Clinical Enzymology.- Biochemical parameters. Markers of function and injury of tissue or organ with particular reference to markers of myocardial damage and markers of liver function.
- Description of the most used techniques in Clinical Biochemistry: Nucleic acids electrophoresis, Protein electrophoresis, Western-blotting , ELISA assay, RIA assay, Fluorescence Microscopy.- Basic elements of Molecular Biology (genome, gene, mutations, polymorphisms) and utilization of databases (eg. NCBI, Enseble Genome Browser, Globin Gene Server).- Integration between Clinical Biochemistry methods and Molecular Biology methods : Study of Hemoglobinopathies- Description of the most used techniques in Molecular Diagnostics:end-point PCR , Real-Time PCR, dHPLC, DNA sequencing (Sanger method) , NGS (Next Generation Sequencing). - Reference texts
- Slides and notes provided by teacher
- Educational objectives
- The main aim of this teaching is to provide students with the theoretical principles useful to identify and analyze the sources of variability of laboratory data and to provide students with the theoretical principles needed to understand the applications and issues that underlie the methods most used in Clinical Biochemistry and Molecular Biology.
The program includes the presentation of some investigation methods of laboratory, their application in the diagnosis of diseases. The main knowledge acquired will be:- Basic knowledge about the collection, processing and storage of biological samples.- Knowledge related to units of measurement in Clinical Biochemistry, sources of preanalytical variability, reference values, biological variability.- Basic concepts of reliability analytical precision, accuracy, sensitivity, specificity.- Basic elements about quality management , predictive value and decision-making levels.- Basic knowledge of Methods used in Clinical Biochemistry:Centrifugation techniques, UV-Visible spectrophotometry and spectrofluorimetry.- Basic knowledge of Clinical Enzymology: enzyme assay, markers of tissue and organ.
- Basic knowledge of Methods used in Clinical Biochemistry:
Nucleic acids and protein electrophoresis, Western-blotting, ELISA, RIA and TestFluorescence microscopy.
- Basic knowledge of Methods used in Clinical Molecular Biology:
End-point PCR, Real-Time PCR, dHPLC, DNA sequencing using Sanger method,NGS (Next Generation Sequencing).
- Basic elements of Molecular Biology (genome, gene, mutations, polymorphisms) and utilization of databases (eg. NCBI, Enseble Genome Browser, Globin Gene Server). - Prerequisites
- The course requires basic knowledge of Biochemistry, Cell Biology and Genetics.
- Teaching methods
- Lectures on all subjects of the couse.
- Learning verification modality
- Multiple choice written test: 30 questions relating to all aspects covered during the course (1 point for each question).
FINAL MARK: arithmetic mean of the marks obtained in the individual disciplines (Clinical Microbiology, Clinical Pathology, Clinical Biochemistry). - Extended program
- - Generation of laboratory data and its critical interpretation.- Reliability of test results: precision, accuracy, sensitivity, specificity.- Quality management, predictive value and decision-making levels.- Units of measurement in Clinical Biochemistry, sources of preanalytical variability, reference values, Biological variability.- Principles and techniques for collecting, processing and storage of biological samples.- Methods used in Clinical Biochemistry:Centrifugation techniques, UV-Visible spectrophotometry and Spectrofluorimetry- Point-of-Care testing, Chemical dry state.- Clinical Enzymology.- Biochemical parameters. Markers of function and injury of tissue or organ with particular reference to markers of myocardial damage and markers of liver function.
- Description of the most used techniques in Clinical Biochemistry: Nucleic acids electrophoresis, Protein electrophoresis, Western-blotting , ELISA assay, RIA assay, Fluorescence Microscopy.- Basic elements of Molecular Biology (genome, gene, mutations, polymorphisms) and utilization of databases (eg. NCBI, Enseble Genome Browser, Globin Gene Server).- Integration between Clinical Biochemistry methods and Molecular Biology methods : Study of Hemoglobinopathies- Description of the most used techniques in Molecular Diagnostics:end-point PCR , Real-Time PCR, dHPLC, DNA sequencing (Sanger method) , NGS (Next Generation Sequencing). - Obiettivi Agenda 2030 per lo sviluppo sostenibile
- Good Health and well-being
Cognomi M-Z
- CFU
- 2
- Teacher
- Paolo Gorello
- Teachers
- Paolo Gorello
- Hours
- 25 ore - Paolo Gorello
- Language of instruction
- Italian
- Contents
- - Generation of laboratory data and its critical interpretation.- Reliability of test results: precision, accuracy, sensitivity, specificity.- Quality management, predictive value and decision-making levels.- Units of measurement in Clinical Biochemistry, sources of preanalytical variability, reference values, Biological variability.- Principles and techniques for collecting, processing and storage of biological samples.- Methods used in Clinical Biochemistry:Centrifugation techniques, UV-Visible spectrophotometry and Spectrofluorimetry- Point-of-Care testing, Chemical dry state.- Clinical Enzymology.- Biochemical parameters. Markers of function and injury of tissue or organ with particular reference to markers of myocardial damage and markers of liver function.
- Description of the most used techniques in Clinical Biochemistry: Nucleic acids electrophoresis, Protein electrophoresis, Western-blotting , ELISA assay, RIA assay, Fluorescence Microscopy.- Basic elements of Molecular Biology (genome, gene, mutations, polymorphisms) and utilization of databases (eg. NCBI, Enseble Genome Browser, Globin Gene Server).- Integration between Clinical Biochemistry methods and Molecular Biology methods : Study of Hemoglobinopathies- Description of the most used techniques in Molecular Diagnostics:end-point PCR , Real-Time PCR, dHPLC, DNA sequencing (Sanger method) , NGS (Next Generation Sequencing). - Reference texts
- Slides and notes provided by teacher
- Educational objectives
- The main aim of this teaching is to provide students with the theoretical principles useful to identify and analyze the sources of variability of laboratory data and to provide students with the theoretical principles needed to understand the applications and issues that underlie the methods most used in Clinical Biochemistry and Molecular Biology.
The program includes the presentation of some investigation methods of laboratory, their application in the diagnosis of diseases. The main knowledge acquired will be:- Basic knowledge about the collection, processing and storage of biological samples.- Knowledge related to units of measurement in Clinical Biochemistry, sources of preanalytical variability, reference values, biological variability.- Basic concepts of reliability analytical precision, accuracy, sensitivity, specificity.- Basic elements about quality management , predictive value and decision-making levels.- Basic knowledge of Methods used in Clinical Biochemistry:Centrifugation techniques, UV-Visible spectrophotometry and spectrofluorimetry.- Basic knowledge of Clinical Enzymology: enzyme assay, markers of tissue and organ.
- Basic knowledge of Methods used in Clinical Biochemistry:
Nucleic acids and protein electrophoresis, Western-blotting, ELISA, RIA and TestFluorescence microscopy.
- Basic knowledge of Methods used in Clinical Molecular Biology:
End-point PCR, Real-Time PCR, dHPLC, DNA sequencing using Sanger method,NGS (Next Generation Sequencing).
- Basic elements of Molecular Biology (genome, gene, mutations, polymorphisms) and utilization of databases (eg. NCBI, Enseble Genome Browser, Globin Gene Server). - Prerequisites
- The course requires basic knowledge of Biochemistry, Cell Biology and Genetics.
- Teaching methods
- Lectures on all subjects of the couse.
- Learning verification modality
- Multiple choice written test: 30 questions relating to all aspects covered during the course (1 point for each question).
FINAL MARK: arithmetic mean of the marks obtained in the individual disciplines (Clinical Microbiology, Clinical Pathology, Clinical Biochemistry). - Extended program
- - Generation of laboratory data and its critical interpretation.- Reliability of test results: precision, accuracy, sensitivity, specificity.- Quality management, predictive value and decision-making levels.- Units of measurement in Clinical Biochemistry, sources of preanalytical variability, reference values, Biological variability.- Principles and techniques for collecting, processing and storage of biological samples.- Methods used in Clinical Biochemistry:Centrifugation techniques, UV-Visible spectrophotometry and Spectrofluorimetry- Point-of-Care testing, Chemical dry state.- Clinical Enzymology.- Biochemical parameters. Markers of function and injury of tissue or organ with particular reference to markers of myocardial damage and markers of liver function.
- Description of the most used techniques in Clinical Biochemistry: Nucleic acids electrophoresis, Protein electrophoresis, Western-blotting , ELISA assay, RIA assay, Fluorescence Microscopy.- Basic elements of Molecular Biology (genome, gene, mutations, polymorphisms) and utilization of databases (eg. NCBI, Enseble Genome Browser, Globin Gene Server).- Integration between Clinical Biochemistry methods and Molecular Biology methods : Study of Hemoglobinopathies- Description of the most used techniques in Molecular Diagnostics:end-point PCR , Real-Time PCR, dHPLC, DNA sequencing (Sanger method) , NGS (Next Generation Sequencing). - Obiettivi Agenda 2030 per lo sviluppo sostenibile
- Good Health and well-being
CLINICAL MICROBIOLOGY
| Code | A001681 |
|---|---|
| CFU | 2 |
| Teacher | Antonella Mencacci |
| Learning activities | Caratterizzante |
| Area | Patologia generale e molecolare, immunopatologia, fisiopatologia generale, microbiologia e parassitologia |
| Academic discipline | MED/07 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 2
- Teacher
- Antonella Mencacci
- Teachers
- Antonella Mencacci
- Hours
- 25 ore - Antonella Mencacci
- Language of instruction
- Italian
- Contents
- Organization and role of the Clinical Microbiology laboratory.
Microbiological diagnostics of organ/system and apparatus infections - Reference texts
- - Microbiologia Medica. Murray PR, Rosenthal LS, Pfaller MA. Edra Masson.
- Principi di Microbiologia Medica, Antonelli G, Clementi M, Pozzi G, Rossolini GM
- Power-point presentations of the face-to-face lessons - Educational objectives
- Knowledge of the various methodological approaches that can be used for the direct and indirect microbiological diagnosis of infectious diseases.
Knowledge of the correct microbiological diagnostic procedures for the etiological diagnosis of infections, with particular reference to the appropriateness of the required tests and the interpretation of the results of microbiological investigations.
• Acquire an adequate diagnostic approach with respect to the infection suspected on a clinical basis
• Knowing how to request microbiological tests
• Knowing how to read and interpret a report. - Prerequisites
- Passing exams in Microbiology and Clinical Biochemistry.
Basic knowledge of Anatomy, Physiology, General Pathology, Immunology. - Teaching methods
- face-to-face lessons and practical activities on the main diagnostic procedures described in the frontal lessons.
- Other information
- Professor receives 30 minutes after each lesson or by appointment made by e-mail.
- Learning verification modality
- ORAL EXAMINATION lasting about 15 min divided into 2 questions, 1 of which relating to the diagnosis of infections of a system/apparatus (see program) and 1 more technical relating to the meaning of a diagnostic technology. A third question on the minimum indispensable knowledge can be made in the case of an unsatisfactory answer to the two questions.
VERIFICATION OF CLINICAL SKILLS: interpretation of a microbiological/antibiogram report
Evaluation of internship activities: a question on microbiological technique or diagnostic process.
Final grade: average of the grades relating to the individual teachings - Extended program
- Organization of the Clinical Microbiology laboratory in diagnostic sectors.
Security level 2 and 3 laboratories.
Direct and indirect diagnosis of bacterial, viral, fungal, protozoal infectious diseases:
Microscopic and culture tests, molecular tests, serological tests, immunodiagnosis.
Antibiogram and detection of antibiotic resistance mechanisms of Gram positive and Gram negative bacteria (methicillin resistance, vancomycin resistance, inducible resistance to macrolides/lincosamides, ESBL, carbapenemase).
Microbiological diagnosis of bacterial, viral, fungal and protozoal infections of the following systems and systems: cardio-circulatory system, urinary system, central nervous system, respiratory system (upper and lower respiratory tract), genitourinary system, gastrointestinal system (notes), infections of wounds and pressure sores, bones and joints (outline). Nosocomial infections and MDRO.
Nosographic classification of each infectious disease (e.g.: sepsis, pneumonia, urinary tract infections, meningitis, septic arthritis, etc.) and of the most appropriate microbiological diagnostic approach. Formulation of the request for microbiological tests and correct reading/interpretation of the report. - Obiettivi Agenda 2030 per lo sviluppo sostenibile
- .
Cognomi M-Z
- CFU
- 2
- Teacher
- Antonella Mencacci
- Teachers
- Antonella Mencacci
- Hours
- 25 ore - Antonella Mencacci
- Language of instruction
- Italian
- Contents
- Organization and role of the Clinical Microbiology laboratory.
Microbiological diagnostics of organ/system and apparatus infections - Reference texts
- - Microbiologia Medica. Murray PR, Rosenthal LS, Pfaller MA. Edra Masson.
- Principi di Microbiologia Medica, Antonelli G, Clementi M, Pozzi G, Rossolini GM
- Power-point presentations of the face-to-face lessons - Educational objectives
- Knowledge of the various methodological approaches that can be used for the direct and indirect microbiological diagnosis of infectious diseases.
Knowledge of the correct microbiological diagnostic procedures for the etiological diagnosis of infections, with particular reference to the appropriateness of the required tests and the interpretation of the results of microbiological investigations.
• Acquire an adequate diagnostic approach with respect to the infection suspected on a clinical basis
• Knowing how to request microbiological tests
• Knowing how to read and interpret a report. - Prerequisites
- Passing exams in Microbiology and Clinical Biochemistry.
Basic knowledge of Anatomy, Physiology, General Pathology, Immunology. - Teaching methods
- face-to-face lessons and practical activities on the main diagnostic procedures described in the frontal lessons.
- Other information
- Professor receives 30 minutes after each lesson or by appointment made by e-mail.
- Learning verification modality
- ORAL EXAMINATION lasting about 15 min divided into 2 questions, 1 of which relating to the diagnosis of infections of a system/apparatus (see program) and 1 more technical relating to the meaning of a diagnostic technology. A third question on the minimum indispensable knowledge can be made in the case of an unsatisfactory answer to the two questions.
VERIFICATION OF CLINICAL SKILLS: interpretation of a microbiological/antibiogram report
Evaluation of internship activities: a question on microbiological technique or diagnostic process.
Final grade: average of the grades relating to the individual teachings - Extended program
- Organization of the Clinical Microbiology laboratory in diagnostic sectors.
Security level 2 and 3 laboratories.
Direct and indirect diagnosis of bacterial, viral, fungal, protozoal infectious diseases:
Microscopic and culture tests, molecular tests, serological tests, immunodiagnosis.
Antibiogram and detection of antibiotic resistance mechanisms of Gram positive and Gram negative bacteria (methicillin resistance, vancomycin resistance, inducible resistance to macrolides/lincosamides, ESBL, carbapenemase).
Microbiological diagnosis of bacterial, viral, fungal and protozoal infections of the following systems and systems: cardio-circulatory system, urinary system, central nervous system, respiratory system (upper and lower respiratory tract), genitourinary system, gastrointestinal system (notes), infections of wounds and pressure sores, bones and joints (outline). Nosocomial infections and MDRO.
Nosographic classification of each infectious disease (e.g.: sepsis, pneumonia, urinary tract infections, meningitis, septic arthritis, etc.) and of the most appropriate microbiological diagnostic approach. Formulation of the request for microbiological tests and correct reading/interpretation of the report. - Obiettivi Agenda 2030 per lo sviluppo sostenibile
- .
CLINICAL PATHOLOGY
| Code | GP005709 |
|---|---|
| CFU | 2 |
| Teacher | Stefano Brancorsini |
| Learning activities | Caratterizzante |
| Area | Medicina di laboratorio e diagnostica integrata |
| Academic discipline | MED/05 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 2
- Teacher
- Stefano Brancorsini
- Teachers
- Stefano Brancorsini
- Hours
- 25 ore - Stefano Brancorsini
- Language of instruction
- Italian
- Contents
- Introduction to clinical pathology and variability in Laboratory Medicine.
Blood count: microcytic, normo macrocytic and hemolytic anemias (hypo/hyperchromic). Thalassemias and hemoglobinopathies.
Coagulation: platelet alterations and coagulation disorders. Laboratory data for the evaluation of pre-thrombotic risks and for the control of anticoagulant therapies
Tumor markers in the diagnosis of neoplastic diseases: nature and classification of tumor markers.
Plasma and serum proteins: diagnostic importance. Notes on serum protein electrophoresis: alterations of plasma proteins and their diagnostic significance.
Clinical enzymology: laboratory evaluation of cardiac and hepatic pathologies.
Laboratory medicine of the kidney: laboratory diagnosis of the main renal pathologies. Urinalysis: composition of normal urine and clinical-diagnostic examination.
Determination and interpretation of hydro-electrolyte balance and blood gas balance: evaluation of homeostasis and alterations of sodium, potassium and acid-base balance.
Laboratory diagnosis of the main alterations of the following glands: pituitary, hypothalamus, thyroid, adrenal and pancreas (diabetes mellitus). - Reference texts
- Federici G. Medicina di laboratorio. McGraw-Hill Editore, 2014.
Pontieri - Russo - Frati e AA.VV., Patologia generale e fisiopatologia generale - II volume. Piccin Editore.
Antonozzi I, Gulletta E. Medicina di Laboratorio. Logica & Patologia clinica. Piccin Editore 2012. - Educational objectives
- Students must be able to understand and interpret the information obtained from laboratory data and associate them with pathophysiological events in order to make a correct diagnosis. At the end of the module, the students' main skills will be the interpretation of biomedical parameters in the diagnosis of renal, cardiac, hepatic, immunological and hematological disorders and adequate knowledge of the use of blood products.
- Prerequisites
- Teaching requires basic knowledge, particularly that deriving from Biochemistry, and the ability to relate it to General Pathology and Physiopathology.
- Teaching methods
- Lectures
- Other information
- Learning verification modality
- Oral test lasting approximately 15 minutes divided into 2 questions, 1 of which relating to the diagnosis of infections of a system/apparatus (v programme) and 1 more technical question relating to the meaning of a diagnostic technology. A further question on the minimum necessary knowledge may be asked in the case of an unsatisfactory answer to the 2 previous questions.
- Extended program
- Introduction to clinical pathology and variability in Laboratory Medicine.
Blood count: microcytic, normo macrocytic and hemolytic anemias (hypo/hyperchromic). Thalassemias and hemoglobinopathies.
Coagulation: platelet alterations and coagulation disorders. Laboratory data for the evaluation of pre-thrombotic risks and for the control of anticoagulant therapies
Tumor markers in the diagnosis of neoplastic diseases: nature and classification of tumor markers.
Plasma and serum proteins: diagnostic importance. Notes on serum protein electrophoresis: alterations of plasma proteins and their diagnostic significance.
Clinical enzymology: laboratory evaluation of cardiac and hepatic pathologies.
Laboratory medicine of the kidney: laboratory diagnosis of the main renal pathologies. Urinalysis: composition of normal urine and clinical-diagnostic examination.
Determination and interpretation of hydro-electrolyte balance and blood gas balance: evaluation of homeostasis and alterations of sodium, potassium and acid-base balance.
Laboratory diagnosis of the main alterations of the following glands: pituitary, hypothalamus, thyroid, adrenal and pancreas (diabetes mellitus). - Obiettivi Agenda 2030 per lo sviluppo sostenibile
Cognomi M-Z
- CFU
- 2
- Teacher
- Stefano Brancorsini
- Teachers
- Stefano Brancorsini
- Hours
- 25 ore - Stefano Brancorsini
- Language of instruction
- Italian
- Contents
- Introduction to clinical pathology and variability in Laboratory Medicine.
Blood count: microcytic, normo macrocytic and hemolytic anemias (hypo/hyperchromic). Thalassemias and hemoglobinopathies.
Coagulation: platelet alterations and coagulation disorders. Laboratory data for the evaluation of pre-thrombotic risks and for the control of anticoagulant therapies
Tumor markers in the diagnosis of neoplastic diseases: nature and classification of tumor markers.
Plasma and serum proteins: diagnostic importance. Notes on serum protein electrophoresis: alterations of plasma proteins and their diagnostic significance.
Clinical enzymology: laboratory evaluation of cardiac and hepatic pathologies.
Laboratory medicine of the kidney: laboratory diagnosis of the main renal pathologies. Urinalysis: composition of normal urine and clinical-diagnostic examination.
Determination and interpretation of hydro-electrolyte balance and blood gas balance: evaluation of homeostasis and alterations of sodium, potassium and acid-base balance.
Laboratory diagnosis of the main alterations of the following glands: pituitary, hypothalamus, thyroid, adrenal and pancreas (diabetes mellitus). - Reference texts
- Federici G. Medicina di laboratorio. McGraw-Hill Editore, 2014.
Pontieri - Russo - Frati e AA.VV., Patologia generale e fisiopatologia generale - II volume. Piccin Editore.
Antonozzi I, Gulletta E. Medicina di Laboratorio. Logica & Patologia clinica. Piccin Editore 2012. - Educational objectives
- Students must be able to understand and interpret the information obtained from laboratory data and associate them with pathophysiological events in order to make a correct diagnosis. At the end of the module, the students' main skills will be the interpretation of biomedical parameters in the diagnosis of renal, cardiac, hepatic, immunological and hematological disorders and adequate knowledge of the use of blood products.
- Prerequisites
- Teaching requires basic knowledge, particularly that deriving from Biochemistry, and the ability to relate it to General Pathology and Physiopathology.
- Teaching methods
- Lectures
- Other information
- Learning verification modality
- Oral test lasting approximately 15 minutes divided into 2 questions, 1 of which relating to the diagnosis of infections of a system/apparatus (v programme) and 1 more technical question relating to the meaning of a diagnostic technology. A further question on the minimum necessary knowledge may be asked in the case of an unsatisfactory answer to the 2 previous questions.
- Extended program
- Introduction to clinical pathology and variability in Laboratory Medicine.
Blood count: microcytic, normo macrocytic and hemolytic anemias (hypo/hyperchromic). Thalassemias and hemoglobinopathies.
Coagulation: platelet alterations and coagulation disorders. Laboratory data for the evaluation of pre-thrombotic risks and for the control of anticoagulant therapies
Tumor markers in the diagnosis of neoplastic diseases: nature and classification of tumor markers.
Plasma and serum proteins: diagnostic importance. Notes on serum protein electrophoresis: alterations of plasma proteins and their diagnostic significance.
Clinical enzymology: laboratory evaluation of cardiac and hepatic pathologies.
Laboratory medicine of the kidney: laboratory diagnosis of the main renal pathologies. Urinalysis: composition of normal urine and clinical-diagnostic examination.
Determination and interpretation of hydro-electrolyte balance and blood gas balance: evaluation of homeostasis and alterations of sodium, potassium and acid-base balance.
Laboratory diagnosis of the main alterations of the following glands: pituitary, hypothalamus, thyroid, adrenal and pancreas (diabetes mellitus). - Obiettivi Agenda 2030 per lo sviluppo sostenibile
PROFESSIONALISING TRAINING IN CLINICAL MICROBIOLOGY
| Code | GP005715 |
|---|---|
| CFU | 1 |
| Teacher | Antonella Mencacci |
| Learning activities | Altro |
| Area | Tirocini formativi e di orientamento |
| Academic discipline | MED/07 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 1
- Teacher
- Antonella Mencacci
- Teachers
- Antonella Mencacci
- Hours
- 25 ore - Antonella Mencacci
- Language of instruction
- Italian
- Contents
- Diagnostic iter related to the microbiological diagnosis of infections.
- Reference texts
- Murray PR, Rosenthal KS, Pfaller MA. Microbiologia Medica, Edra Masson
Antonelli G, Clementi M, Pozzi G, Rossolini G.M. Principi di Microbiologia Medica, CEA - Educational objectives
- The student will have to know the diagnostic procedures, from the collection of the clinical sample to the final reporting of the tests, relating to the following infections: bloodstream infections, meingitis, respiratory infections, urinary tract infections, and skin and soft tissues infections.
- Prerequisites
- General and Systematic Microbiology
- Teaching methods
- Practical acivity at the Microbiology Unit (Perugia General Hospital)
- Other information
- .
- Learning verification modality
- The same as Clinical microbiology
- Extended program
- Diagnostic process for the diagnosis of:
sepsis, pneumonia, meningitis, urinary tract infections, skin and soft tissue infections. - Obiettivi Agenda 2030 per lo sviluppo sostenibile
- .
Cognomi M-Z
- CFU
- 1
- Teacher
- Antonella Mencacci
- Teachers
- Antonella Mencacci
- Hours
- 25 ore - Antonella Mencacci
- Language of instruction
- Italian
- Contents
- Diagnostic procedures related to the microbiological diagnosis of infections of different organs and systems
- Reference texts
- Murray PR, Rosenthal KS, Pfaller MA. Microbiologia Medica, Edra Masson
Antonelli G, Clementi M, Pozzi G, Rossolini G.M. Principi di Microbiologia Medica, CEA
power point presentations of the lessons - Educational objectives
- The student will have to know the diagnostic procedures, from the collection of the clinical sample to the final reporting of the tests, relating to the following infections: bloodstream infections, meingitis, respiratory infections, urinary tract infections, and skin and soft tissues infections.
- Prerequisites
- General and Systematic Microbiology
- Teaching methods
- Practical activity at the Microbiology Unit of the Perugia General Hospital.
- Other information
- .
- Learning verification modality
- see Clinical Microbiology
- Extended program
- Diagnostic process for the diagnosis of:
sepsis, pneumonia, meningitis, urinary tract infections, skin and soft tissue infections. - Obiettivi Agenda 2030 per lo sviluppo sostenibile
- .
PROFESSIONALISING TRAINING IN CLINICAL PATHOLOGY
| Code | GP005714 |
|---|---|
| CFU | 1 |
| Teacher | Stefano Brancorsini |
| Learning activities | Altro |
| Area | Tirocini formativi e di orientamento |
| Academic discipline | MED/05 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 1
- Teacher
- Stefano Brancorsini
- Teachers
- Stefano Brancorsini
- Hours
- 25 ore - Stefano Brancorsini
- Language of instruction
- Italian
- Contents
- Introduction to clinical pathology and variability in Laboratory Medicine.
Blood count: microcytic, normo macrocytic and hemolytic anemias (hypo/hyperchromic). Thalassemias and hemoglobinopathies.
Coagulation: platelet alterations and coagulation disorders. Laboratory data for the evaluation of pre-thrombotic risks and for the control of anticoagulant therapies
Tumor markers in the diagnosis of neoplastic diseases: nature and classification of tumor markers.
Plasma and serum proteins: diagnostic importance. Notes on serum protein electrophoresis: alterations of plasma proteins and their diagnostic significance.
Clinical enzymology: laboratory evaluation of cardiac and hepatic pathologies.
Laboratory medicine of the kidney: laboratory diagnosis of the main renal pathologies. Urinalysis: composition of normal urine and clinical-diagnostic examination.
Determination and interpretation of hydro-electrolyte balance and blood gas balance: evaluation of homeostasis and alterations of sodium, potassium and acid-base balance.
Laboratory diagnosis of the main alterations of the following glands: pituitary, hypothalamus, thyroid, adrenal and pancreas (diabetes mellitus). - Reference texts
- Federici G. Medicina di laboratorio. McGraw-Hill Editore, 2014.
Pontieri - Russo - Frati e AA.VV., Patologia generale e fisiopatologia generale - II volume. Piccin Editore.
Antonozzi I, Gulletta E. Medicina di Laboratorio. Logica & Patologia clinica. Piccin Editore 2012. - Educational objectives
- Students must be able to understand and interpret the information obtained from laboratory data and associate them with pathophysiological events in order to make a correct diagnosis. At the end of the module, the students' main skills will be the interpretation of biomedical parameters in the diagnosis of renal, cardiac, hepatic, immunological and hematological disorders and adequate knowledge of the use of blood products.
- Prerequisites
- Teaching requires basic knowledge, particularly that deriving from Biochemistry, and the ability to relate it to General Pathology and Physiopathology.
- Teaching methods
- Lectures, seminars and attendance in the analysis laboratory
- Other information
- Learning verification modality
- Oral test lasting approximately 15 minutes divided into 2 questions, 1 of which relating to the diagnosis of infections of a system/apparatus (v programme) and 1 more technical question relating to the meaning of a diagnostic technology. A further question on the minimum necessary knowledge may be asked in the case of an unsatisfactory answer to the 2 previous questions. Interpretation of a hematology and clinical chemistry report
Description of a technology or clinical diagnostic process - Extended program
- Introduction to clinical pathology and variability in Laboratory Medicine.
Blood count: microcytic, normo macrocytic and hemolytic anemias (hypo/hyperchromic). Thalassemias and hemoglobinopathies.
Coagulation: platelet alterations and coagulation disorders. Laboratory data for the evaluation of pre-thrombotic risks and for the control of anticoagulant therapies
Tumor markers in the diagnosis of neoplastic diseases: nature and classification of tumor markers.
Plasma and serum proteins: diagnostic importance. Notes on serum protein electrophoresis: alterations of plasma proteins and their diagnostic significance.
Clinical enzymology: laboratory evaluation of cardiac and hepatic pathologies.
Laboratory medicine of the kidney: laboratory diagnosis of the main renal pathologies. Urinalysis: composition of normal urine and clinical-diagnostic examination.
Determination and interpretation of hydro-electrolyte balance and blood gas balance: evaluation of homeostasis and alterations of sodium, potassium and acid-base balance.
Laboratory diagnosis of the main alterations of the following glands: pituitary, hypothalamus, thyroid, adrenal and pancreas (diabetes mellitus). - Obiettivi Agenda 2030 per lo sviluppo sostenibile
Cognomi M-Z
- CFU
- 1
- Teacher
- Stefano Brancorsini
- Teachers
- Stefano Brancorsini
- Hours
- 25 ore - Stefano Brancorsini
- Language of instruction
- Italian
- Contents
- Introduction to clinical pathology and variability in Laboratory Medicine.
Blood count: microcytic, normo macrocytic and hemolytic anemias (hypo/hyperchromic). Thalassemias and hemoglobinopathies.
Coagulation: platelet alterations and coagulation disorders. Laboratory data for the evaluation of pre-thrombotic risks and for the control of anticoagulant therapies
Tumor markers in the diagnosis of neoplastic diseases: nature and classification of tumor markers.
Plasma and serum proteins: diagnostic importance. Notes on serum protein electrophoresis: alterations of plasma proteins and their diagnostic significance.
Clinical enzymology: laboratory evaluation of cardiac and hepatic pathologies.
Laboratory medicine of the kidney: laboratory diagnosis of the main renal pathologies. Urinalysis: composition of normal urine and clinical-diagnostic examination.
Determination and interpretation of hydro-electrolyte balance and blood gas balance: evaluation of homeostasis and alterations of sodium, potassium and acid-base balance.
Laboratory diagnosis of the main alterations of the following glands: pituitary, hypothalamus, thyroid, adrenal and pancreas (diabetes mellitus). - Reference texts
- Federici G. Medicina di laboratorio. McGraw-Hill Editore, 2014.
Pontieri - Russo - Frati e AA.VV., Patologia generale e fisiopatologia generale - II volume. Piccin Editore.
Antonozzi I, Gulletta E. Medicina di Laboratorio. Logica & Patologia clinica. Piccin Editore 2012. - Educational objectives
- Students must be able to understand and interpret the information obtained from laboratory data and associate them with pathophysiological events in order to make a correct diagnosis. At the end of the module, the students' main skills will be the interpretation of biomedical parameters in the diagnosis of renal, cardiac, hepatic, immunological and hematological disorders and adequate knowledge of the use of blood products.
- Prerequisites
- Teaching requires basic knowledge, particularly that deriving from Biochemistry, and the ability to relate it to General Pathology and Physiopathology.
- Teaching methods
- Lectures, seminars and attendance in the analysis laboratory
- Other information
- Learning verification modality
- Oral test lasting approximately 15 minutes divided into 2 questions, 1 of which relating to the diagnosis of infections of a system/apparatus (v programme) and 1 more technical question relating to the meaning of a diagnostic technology. A further question on the minimum necessary knowledge may be asked in the case of an unsatisfactory answer to the 2 previous questions. Interpretation of a hematology and clinical chemistry report
Description of a technology or clinical diagnostic process - Extended program
- Introduction to clinical pathology and variability in Laboratory Medicine.
Blood count: microcytic, normo macrocytic and hemolytic anemias (hypo/hyperchromic). Thalassemias and hemoglobinopathies.
Coagulation: platelet alterations and coagulation disorders. Laboratory data for the evaluation of pre-thrombotic risks and for the control of anticoagulant therapies
Tumor markers in the diagnosis of neoplastic diseases: nature and classification of tumor markers.
Plasma and serum proteins: diagnostic importance. Notes on serum protein electrophoresis: alterations of plasma proteins and their diagnostic significance.
Clinical enzymology: laboratory evaluation of cardiac and hepatic pathologies.
Laboratory medicine of the kidney: laboratory diagnosis of the main renal pathologies. Urinalysis: composition of normal urine and clinical-diagnostic examination.
Determination and interpretation of hydro-electrolyte balance and blood gas balance: evaluation of homeostasis and alterations of sodium, potassium and acid-base balance.
Laboratory diagnosis of the main alterations of the following glands: pituitary, hypothalamus, thyroid, adrenal and pancreas (diabetes mellitus). - Obiettivi Agenda 2030 per lo sviluppo sostenibile