Unit GENERAL CHEMISTRY AND CHEMICAL LABORATORY
- Course
- Biomedical laboratory techniques
- Study-unit Code
- A003222
- Curriculum
- In all curricula
- Teacher
- Veronica Ceccarelli
- CFU
- 5
- Course Regulation
- Coorte 2023
- Offered
- 2023/24
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa integrata
GENERAL CHEMISTRY
| Code | GP003081 |
|---|---|
| CFU | 4 |
| Teacher | Veronica Ceccarelli |
| Teachers |
|
| Hours |
|
| Learning activities | Base |
| Area | Scienze biomediche |
| Academic discipline | BIO/10 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian |
| Contents | The program covers the main topics of General and Inorganic Chemistry: structure of the atom, chemical bonds, solutions, pH of acids and bases, salt hydrolysis and buffer systems. Organic Chemistry: structure and chemical properties of alcohols, aldehydes and ketones, carboxylic acid amines and carboxylic acid derivatives. Structure and characteristics of carbohydrates. Lipids. Amino acids and protein. Nucleotides and nucleic acids |
| Reference texts | Chimica e Propedeutica Biochimica L. Binaglia, B. Giardina - Ed. Mc Graw Hill |
| Educational objectives | The main competence will be to have a general knowledge necessary to address the Biochemistry lessons |
| Prerequisites | Basic knowledge of the basic principles of chemistry and mathematics studied for the examination of access to the degree course |
| Teaching methods | The course is organized in lectures on all the topics of the program; during the lessons the student is encouraged to intervene for the clarification request |
| Other information | The attendance is compulsory at least 75% of lessons |
| Learning verification modality | The final exam consists of writing and an oral test |
| Extended program | Atom structure: Nucleus and atomic orbitals Periodic table of the elements. Stable and radioactive isotopes. Mole and Avogadro number. Covalent and ionic chemical bonds. Electronegativity of the elements and polarity of the molecules. Hybridization of orbitals and geometry of molecules. Resonance and links to delocalized electrons. Intermolecular bonds. Nomenclature of inorganic compounds. States of aggregation of matter; internal pressure and condensation process of real gases, changes in status. Properties of liquids and solutions. Unit of concentration of solutions, vapor pressure, surface tension, osmotic pressure. Electrolytes and chemical equilibria in solution. Acids and bases. Calculation of the pH of solutions of acids, bases and salts. Acid-base buffers. Laws of chemical kinetics and their use in the biochemical-clinical laboratory. Oxidation-reduction processes of biomedical interest. Structure and nomenclature of alkanes, alkenes, alkynes, cycloalkanes, aromatic hydrocarbons. Conformational stereoisomerism. Geometric configurational stereoisomerism. Main reactions of the different classes of hydrocarbons: substitution and addition reactions. Optical stereoisomerism: Fischer convention and R / S convention. Structure and chemical properties of the functional groups: Alcoholic, thiol and phenol, Ethereal and thioethyl, Amino, Carbonyl, Carboxylic, ester and amide. Heterocyclic compounds. Thermodynamics of reactions. Carbohydrates. Lipids. Amino acids and proteins. Nucleotides and nucleic acids |
| Obiettivi Agenda 2030 per lo sviluppo sostenibile | Health and wellness, clean water and life on earth |
ELEMENTS OF INSTRUMENT CHEMISTRY
| Code | A001512 |
|---|---|
| CFU | 1 |
| Teacher | Gianluca Curti |
| Teachers |
|
| Hours |
|
| Learning activities | Caratterizzante |
| Area | Scienze della prevenzione e dei servizi sanitari |
| Academic discipline | MED/50 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian |
| Contents | General introduction to instrumental chemistry. |
| Reference texts | Lecture notes provided by the instructor. Study materials are published on Unistudium. |
| Educational objectives | The main objective of this course is to provide students with the fundamental knowledge of instrumental chemistry, which is a crucial prerequisite for further exploration of the use of analytical instrumentation in the biomedical laboratory. D1. Knowledge and Understanding The primary knowledge acquired will be in the field of important instrumental techniques. D2. Application of Knowledge and Understanding Engaging in relevant exercises related to the topics covered in the lectures provides students with the opportunity to assess and verify the acquired knowledge. D3. Autonomy of Judgment The course aims to encourage students to personally rework the topics discussed in the lectures, supported by interaction with the instructor. D4. Communication Skills The student will need to acquire the ability to present the course topics clearly and with linguistic accuracy, using the formalism of the subject matter correctly. D5. Learning Skills At the end of the course, the student will be capable of applying the basic concepts of instrumental chemistry to further develop specific competencies in the field of the biomedical laboratory, particularly cultivating a critical sense that allows for the evaluation of the potential, advantages, and limitations of the various studied analytical techniques. |
| Prerequisites | |
| Teaching methods | The course is structured as follows: - Classroom lectures (10 hours) covering the topics outlined in the course syllabus, supported by PowerPoint presentations and the blackboard. At the end of each topic, examples will be provided with the aim of facilitating, deepening, and enhancing the learning process. |
| Other information | |
| Learning verification modality | Practical exercises (2 hours) involving the resolution of analytical questions. Students may be divided into groups as needed. |
| Extended program | Essential Concepts Underlying Instrumental Chemistry Introduction Main Analytical Techniques Analysis of Chemical Species of Biological Interest Pre-analytical and Analytical Issues The Impact of Information Technologies Atomic Absorption Spectrophotometry General Principles Instrumentation Method Development Applications in Trace Element Analysis in Biological Matrices UV-Vis Spectrophotometry General Principles Applications in the Field of Occupational and Environmental Toxicology Chromatography General Principles Classification of Chromatographic Methods HPLC Instrumentation Method Development Applications in the Field of Occupational and Environmental Toxicology Gas Chromatography Instrumentation Method Development Applications in the Field of Occupational and Environmental Toxicology Mass Spectrometry General Principles Gas Chromatography Coupled with Mass Spectrometry GC-MS Instrumentation Method Development Applications in the Field of Occupational and Environmental Toxicology Liquid Chromatography Coupled with Mass Spectrometry LC-MS Instrumentation Method Development Applications in the Field of Occupational and Environmental Toxicology |
| Obiettivi Agenda 2030 per lo sviluppo sostenibile |