Unit BIOTECHNOLOGY IN HEMOSTASIS AND THROMBOSIS
- Course
- Medical, veterinary and forensic biotechnological sciences
- Study-unit Code
- A001764
- Curriculum
- Medico
- Teacher
- Loredana Bury
- Teachers
-
- Loredana Bury
- Hours
- 52 ore - Loredana Bury
- CFU
- 6
- Course Regulation
- Coorte 2024
- Offered
- 2025/26
- Learning activities
- Caratterizzante
- Area
- Discipline medico-chirurgiche e riproduzione umana
- Sector
- MED/46
- Type of study-unit
- Opzionale (Optional)
- Type of learning activities
- Attività formativa monodisciplinare
- Language of instruction
- English
- Contents
- - Primary Hemostasis – Platelet structure and function - Megakaryocytopoiesis and proplatelet formation - Hereditary platelet disorders - Screening and first level tests for the study of platelets - Second level tests for the study of platelets - Secondary Hemostasis – The coagulation cascade - Molecular genetic diagnosis of inherited bleeding and thrombotic disorders - Deep vein thrombosis and thrombophilias - Thrombotic thrombocytopenias (TTP, HIT, VITT) - Immune thrombocytopenia (ITP) - Micro-RNA in haemostasis and thrombosis - Alternative functions of platelets - Congenital haemorrhagic diseases and acquired coagulopathies - Cellular models for therapeutic approaches to hemorrhagic disorders
- Reference texts
- The teacher will prepare the didactic materials on the basis of the scientific literature available on the specific topics. Accordingly, participation to the teacher's lessons is essential. On specific topics, references to specific articles or textbooks will be provided.
- Educational objectives
- The course aims to provide students with the basic knowledge on the diagnostic and therapeutic techniques the most update biotechnological method in the field of hemostasis and thrombosis.
- Prerequisites
- General biology, molecular biology, principles of general anatomy and physiology.
- Teaching methods
- Didactic activity will be mainly focused on face-to-face lessons using Power Point slides, practical lessons will be made at the Hemostasis and Thrombosis Centre.
- Other information
- The attendance of the lessons is warmly suggested in order to allow a good understanding of the arguments in the absence of a single reference textbook.
- Learning verification modality
- Multiple choice and free text, written assessment. For information about support services for students with disabilities and/or specific learning disorders (SLD), please visit the page: http://www.unipg.it/disabilita-e-dsa
- Extended program
- The hemostatic process: physiolpathology and clinical aspects.Approach to the patient with suspected hemorrhagic disorders. Main diseases in the field of hemostasis and thrombosis (genetic and acquired hemorrhagic disorders);Megacaryocytes and piastrinopoiesis. Cellular models for the study of inherited platelet disorders. Flow cytometry applied to the study of hemostasis. Diagnostic tests for platelet disorders. Venous thromboembolism and the study of congenital and acquired thrombophilia. MicroRNA in hemostasis and thrombosis. Molecular biology techniques applied to hemostasis and thrombosis. Immune-based thrombocytopenias, with a particular focus on immune thrombocytopenia (ITP). Alternative functions of platelets. Innovative treatments for bleeding disorders (gene therapy, bispecific antibodies, etc.).
- Obiettivi Agenda 2030 per lo sviluppo sostenibile
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