Unit HERBAL PRODUCTS TOSSICOLOGY
- Course
- Pharmacy
- Study-unit Code
- A000578
- Location
- PERUGIA
- Curriculum
- In all curricula
- Teacher
- Claudia Zadra
- Teachers
-
- Claudia Zadra
- Hours
- 28 ore - Claudia Zadra
- CFU
- 4
- Course Regulation
- Coorte 2018
- Offered
- 2021/22
- Learning activities
- Affine/integrativa
- Area
- Attività formative affini o integrative
- Academic discipline
- AGR/13
- Type of study-unit
- Opzionale (Optional)
- Type of learning activities
- Attività formativa monodisciplinare
- Language of instruction
- Italian
- Contents
- Biotransformation of the active ingredients in the complementary medicines and their possible toxic effects.
Occurrence of residues and contaminants in medicinal herbs: source, class of contaminants (heavy metals, pesticides, mycotoxins..) and regulatory limits. Adverse effects of these xenobiotic for the human health. - Reference texts
- Casarett & Doull’s Toxicology -The basic science of poisons
Melis - Additivi e tossici negli alimenti - Educational objectives
- One of the goals of the course is to provide information about the biotransformation reactions of the active ingredients with particular attention for the possible toxic effects of some metabolites.
Another topic is to focus critical aspects in terms of the presence of contaminants in botanicals, with respect to their origin, presence in the environment or during the manufacturing process. - Prerequisites
- The student is requested to know Chemistry, Organic Chemistry and Botany
- Teaching methods
- frontal lectures
- Learning verification modality
- oral examination
- Extended program
- General principles of environmental and food contaminations; risk analysis; risk assessment;
Biotransformation of xenobiotics.
Natural toxicants (Terpenes, Phenylpropanoids, coumarins, nitrates, nitrosamines, cyanogenic compounds, alkaloids).
MICROPOLLUTANTS (heavy metals, dioxins and dioxins compounds like, PAH)
PESTICIDES (environmental fate, Herbicides, Insecticides, Fungicides ,
Pesticides in botanicals
MRLs, )