Unit PHYSIOLOGY
- Course
- Biological sciences
- Study-unit Code
- 55042808
- Curriculum
- In all curricula
- Teacher
- Fabio Franciolini
- Teachers
-
- Fabio Franciolini
- Hours
- 56 ore - Fabio Franciolini
- CFU
- 8
- Course Regulation
- Coorte 2015
- Offered
- 2017/18
- Learning activities
- Caratterizzante
- Area
- Discipline fisiologiche e biomediche
- Academic discipline
- BIO/09
- Type of study-unit
- Opzionale (Optional)
- Type of learning activities
- Attività formativa monodisciplinare
- Language of instruction
Italian- Contents
Cellular and molecular basis of cell excitability, synaptic transmission and muscle contraction- Reference texts
Fisiologia. Edi.Ermes, Milano - 2011. A cura di Egidio D'Angelo e Antonio Peres- Educational objectives
The course tackle the basic aspects of the mechanisms involved in cell excitability, and muscle contraction. The strongly interactive lectures will instill - that's the objective - in students the attitude and needs towards a rigorous approach of the fundamentals underlying each process, mechanism and function, the only one leading to the development of a conscious attitude towards things.- Prerequisites
Basic knowledge of Physics, Chemistry, Biology- Teaching methods
Class lectures, lab classes- Other information
N/A- Learning verification modality
Oral exam to evaluate the presentation ability, the logical approach to science, and the knowledge of the field- Extended program
1 - Central issues in Physiology Structure-function relationship Organizational levels and reductionism Omeostasis 3 – Cell membrane and transport Intra and extracellular environment Membrane permeation Active transport 4 – Membrane electrical processes Nernst equation Donnan equilibrium Generation of membrane potential 5 – Neural cells and signals Cell types of the nervous system Electrical signals All-or-nothing impulse Action potential Action potential propagation 6 – Ion channels Structure of ion channels and receptors Structure of voltage-gated channels Conformational transition of ion channels Voltage-dependent gating Ligand-dependent gating 7 – Cell communication Signal transduction Prevalent ligand types Seven TM receptors Chemical neurotransmission Ionotropic and metabotropic receptors 8 – Neurotransmission and synaptic plasticity Properties of chemical synapses Sequence of events in neurotransmission Calcium signals in presynaptic terminal Neurotransmitter release and reuptake Postsynaptic receptor activation Synaptic plasticity 10 – Muscle contration Muscle contraction Structure of skeletal muscle fibers Structure-function relationship in muscle Molecular mechanism of muscle contration Modulation of contraction and role of calcium E-C coupling in skeletal muscle and in myocardium General properties of smooth muscle