Unit PHARMACOLOGY
- Course
- Medicine and surgery
- Study-unit Code
- GP004550
- Location
- PERUGIA
- Curriculum
- In all curricula
- Teacher
- Graziella Migliorati
- CFU
- 13
- Course Regulation
- Coorte 2018
- Offered
- 2021/22
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa integrata
PHARMACOLOGY - MOD. 1
| Code | GP004575 |
|---|---|
| Location | PERUGIA |
| CFU | 2 |
| Teacher | Graziella Migliorati |
| Teachers |
|
| Hours |
|
| Learning activities | Caratterizzante |
| Area | Farmacologia, tossicologia e principi di terapia medica |
| Academic discipline | BIO/14 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian |
| Contents | General principles Pharmacokinetics Pharmacodynamics Molecular mechanisms of drug action |
| Reference texts | Reccomended reading: - F. Rossi, V. Cuomo, C. Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, IV Edizione, Edizioni Minerva Medica - B.G. Katzung, A.J. Trevor, Farmacologia generale e clinica, X edizione, PICCIN Reference books: - A. Goodman & Gilman, Le basi farmacologiche della terapia, XIII edizione, Zanichelli - F. Clementi, G. Fumagalli, Farmacologia generale e molecolare, V edizione, Edra |
| Educational objectives | At the end of the course students will have learned the pharmacodynamics, pharmacokinetics, undesirable side effects, toxicological aspects, the therapeutic foundations and methods of administration of drugs most important in medical practice. Should be aware of the factors that influence the pharmacological effect and / or therapeutic, as well as the risk / benefit ratio of drug therapy. Must know how to make a reasoned choice of drugs in relation to different pathological situations. |
| Prerequisites | In order to achieve the intended learning outcomes, the student must have a solid background in anatomy, physiology and general pathology. The student must have already passed the other exams considered as preparatory by the Academic Regulations. |
| Teaching methods | lessons face-to-face Mandatory attendence |
| Learning verification modality | Written exam and oral exam The test focuses globally on the entire program. The test consists of 62 multiple choice quiz with five possible answers of which only one is correct; The exam duration time is 1 hour and 15 minutes. For the evaluation of the test takes into account the following criteria: - 0.5 points for each correct answer; - Less than 0.1 points for each wrong answer; - 0 points for each question not answered; The written exam is passed if for each test is obtained a score of at least 18/30. The oral test is mandatory, concerns topics of the entire program and is primarily designed to evaluate the ability to apply their knowledge for the proper use of the drugs in clinical practice. Final vote accounts for 40% of the vote overall written test and 60% vote of the oral test. |
| Extended program | General principles Origin and Drug Classification Pharmacokinetics Routes of administration Absorption, bioavailability Distribution Metabolism Elimination Main pharmacokinetic parameters: volume of distribution, half-life, clearance Pharmacokinetics quantitative kinetics of zero order and first order Clinical pharmacokinetics, kinetics of the drug administered in repeated doses, the concept of steady state Pharmacodynamics Drug-drug interaction recetthours Agonists, antagonists, partial agonists and inverse Dose-response curves and curves quantal Affinity, potency, efficacy, therapeutic index Molecular structure of receptors Mechanisms of signal transduction Regulation of receptor response Mechanism of action of drugs and correlation between concentration and pharmacological effect of drugs |
PHARMACOLOGY - MOD. 2
| Code | GP004576 |
|---|---|
| Location | PERUGIA |
| CFU | 2 |
| Teacher | Graziella Migliorati |
| Teachers |
|
| Hours |
|
| Learning activities | Caratterizzante |
| Area | Farmacologia, tossicologia e principi di terapia medica |
| Academic discipline | BIO/14 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian |
| Contents | Principles of clinical pharmacology and therapy Drugs acting at synaptic and neuroeffector junctions |
| Reference texts | Reccomended reading: - F. Rossi, V. Cuomo, C. Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, IV Edizione, Edizioni Minerva Medica - B.G. Katzung, A.J. Trevor, Farmacologia generale e clinica, X edizione, PICCIN Reference books: - A. Goodman & Gilman, Le basi farmacologiche della terapia, XIII edizione, Zanichelli - F. Clementi, G. Fumagalli, Farmacologia generale e molecolare, V edizione, Edra |
| Educational objectives | At the end of the course students will have learned the pharmacodynamics, pharmacokinetics, undesirable side effects, toxicological aspects, the therapeutic foundations and methods of administration of drugs most important in medical practice. Should be aware of the factors that influence the pharmacological effect and / or therapeutic, as well as the risk / benefit ratio of drug therapy. Must know how to make a reasoned choice of drugs in relation to different pathological situations. |
| Prerequisites | In order to achieve the intended learning outcomes, the student must have a solid background in anatomy, physiology and general pathology. The student must have already passed the other exams considered as preparatory by the Academic Regulations. |
| Teaching methods | lessons face-to-face Mandatory attendence |
| Learning verification modality | Written exam and oral exam The test focuses globally on the entire program. The test consists of 62 multiple choice quiz with five possible answers of which only one is correct; The exam duration time is 1 hour and 15 minutes. For the evaluation of the test takes into account the following criteria: - 0.5 points for each correct answer; - Less than 0.1 points for each wrong answer; - 0 points for each question not answered; The written exam is passed if for each test is obtained a score of at least 18/30. The oral test is mandatory, concerns topics of the entire program and is primarily designed to evaluate the ability to apply their knowledge for the proper use of the drugs in clinical practice. Final vote accounts for 40% of the vote overall written test and 60% vote of the oral test. |
| Extended program | Principles of clinical pharmacology and therapy Adverse drug reaction Variability in individual response to drugs: pharmacokinetic and pharmacodynamic variables, tolerance Pharmacogenetics Drug interactions Drugs acting at synaptic and neuroeffector junctions Neurohumoral transmission: the autonomic and somatic motor Cholinergic Agonists Anticholinesterases Muscarinic antagonists Drugs acting on the neuromuscular junction and autonomic ganglia Catecholamines and sympathomimetic drugs Adrenergic neuron antagonist |
PHARMACOLOGY - MOD. 3
| Code | GP004577 |
|---|---|
| Location | PERUGIA |
| CFU | 2 |
| Teacher | Graziella Migliorati |
| Teachers |
|
| Hours |
|
| Learning activities | Caratterizzante |
| Area | Farmacologia, tossicologia e principi di terapia medica |
| Academic discipline | BIO/14 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian |
| Contents | Cardiovascular system drugs |
| Reference texts | Reccomended reading: - F. Rossi, V. Cuomo, C. Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, IV Edizione, Edizioni Minerva Medica - B.G. Katzung, A.J. Trevor, Farmacologia generale e clinica, X edizione, PICCIN Reference books: - A. Goodman & Gilman, Le basi farmacologiche della terapia, XIII edizione, Zanichelli - F. Clementi, G. Fumagalli, Farmacologia generale e molecolare, V edizione, Edra |
| Educational objectives | At the end of the course students will have learned the pharmacodynamics, pharmacokinetics, undesirable side effects, toxicological aspects, the therapeutic foundations and methods of administration of drugs most important in medical practice. Should be aware of the factors that influence the pharmacological effect and / or therapeutic, as well as the risk / benefit ratio of drug therapy. Must know how to make a reasoned choice of drugs in relation to different pathological situations. |
| Prerequisites | In order to achieve the intended learning outcomes, the student must have a solid background in anatomy, physiology and general pathology. The student must have already passed the other exams considered as preparatory by the Academic Regulations. |
| Teaching methods | lessons face-to-face Mandatory attendence |
| Learning verification modality | Written exam and oral exam The test focuses globally on the entire program. The test consists of 62 multiple choice quiz with five possible answers of which only one is correct; The exam duration time is 1 hour and 15 minutes. For the evaluation of the test takes into account the following criteria: - 0.5 points for each correct answer; - Less than 0.1 points for each wrong answer; - 0 points for each question not answered; The written exam is passed if for each test is obtained a score of at least 18/30. The oral test is mandatory, concerns topics of the entire program and is primarily designed to evaluate the ability to apply their knowledge for the proper use of the drugs in clinical practice. Final vote accounts for 40% of the vote overall written test and 60% vote of the oral test. |
| Extended program | Cardiovascular system drugs Drugs that affect renal function and electrolyte metabolism Pharmacological control of the renin-angiotensin-aldosterone Antihypertensive drugs Antianginal drugs Cardiac glycosides Antiarrhythmic drugs Drugs for treatment of dyslipidemia |
PHARMACOLOGY - MOD. 4
| Code | GP004578 |
|---|---|
| Location | PERUGIA |
| CFU | 3 |
| Teacher | Graziella Migliorati |
| Teachers |
|
| Hours |
|
| Learning activities | Caratterizzante |
| Area | Farmacologia, tossicologia e principi di terapia medica |
| Academic discipline | BIO/14 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian |
| Contents | Drugs acting on the central nervous system Autacoids and anti-inflammatory drugs Drugs that affect gastrointestinal function Pharmacology of the immune system Drugs acting on blood and blood-forming organs |
| Reference texts | Reccomended reading: - F. Rossi, V. Cuomo, C. Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, IV Edizione, Edizioni Minerva Medica - B.G. Katzung, A.J. Trevor, Farmacologia generale e clinica, X edizione, PICCIN Reference books: - A. Goodman & Gilman, Le basi farmacologiche della terapia, XIII edizione, Zanichelli - F. Clementi, G. Fumagalli, Farmacologia generale e molecolare, V edizione, Edra |
| Educational objectives | At the end of the course students will have learned the pharmacodynamics, pharmacokinetics, undesirable side effects, toxicological aspects, the therapeutic foundations and methods of administration of drugs most important in medical practice. Should be aware of the factors that influence the pharmacological effect and / or therapeutic, as well as the risk / benefit ratio of drug therapy. Must know how to make a reasoned choice of drugs in relation to different pathological situations. |
| Prerequisites | In order to achieve the intended learning outcomes, the student must have a solid background in anatomy, physiology and general pathology. The student must have already passed the other exams considered as preparatory by the Academic Regulations. |
| Teaching methods | lessons face-to-face Mandatory attendence |
| Learning verification modality | Written exam and oral exam The test focuses globally on the entire program. The test consists of 62 multiple choice quiz with five possible answers of which only one is correct; The exam duration time is 1 hour and 15 minutes. For the evaluation of the test takes into account the following criteria: - 0.5 points for each correct answer; - Less than 0.1 points for each wrong answer; - 0 points for each question not answered; The written exam is passed if for each test is obtained a score of at least 18/30. The oral test is mandatory, concerns topics of the entire program and is primarily designed to evaluate the ability to apply their knowledge for the proper use of the drugs in clinical practice. Final vote accounts for 40% of the vote overall written test and 60% vote of the oral test. |
| Extended program | Drugs acting on the central nervous system Neurotransmission and the central nervous system Anxiolytics and sedative-hypnotics Drugs of Affective Disorders, antipsychotics, antidepressants Drugs for the treatment of migraine and the control of vomiting Pharmacology of analgesia Autacoids and anti-inflammatory drugs General information on inflammation and mediators involved Histamine and antihistamines Non-steroidal anti-inflammatory drugs, drugs used in the treatment of rheumatoid arthritis and gout Steroidal anti-inflammatory drugs Drugs used to treat asthma Drugs that affect gastrointestinal function Antiulcer drugs Drugs that affect gastrointestinal motility Pharmacology of the immune system Serums and Vaccines Immunosuppressants and immunostimulants Drugs acting on blood and blood-forming organs Emopietici agents: growth factors and vitamins Anticoagulants, thrombolytics, and antiplatelet |
PHARMACOLOGY - MOD. 5
| Code | GP004579 |
|---|---|
| Location | PERUGIA |
| CFU | 3 |
| Teacher | Graziella Migliorati |
| Learning activities | Caratterizzante |
| Area | Formazione clinica interdisciplinare e medicina basata sulle evidenze |
| Academic discipline | BIO/14 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 3
- Teacher
- Emira Maria Ayroldi
- Teachers
- Graziella Migliorati (Codocenza)
- Emira Maria Ayroldi
- Hours
- 12.5 ore (Codocenza) - Graziella Migliorati
- 25 ore - Emira Maria Ayroldi
- Language of instruction
- Italian
- Contents
- Drugs acting on the central nervous system
Endocrine Drugs
Drugs affecting uterine motility
Chemotherapy - Reference texts
- Reccomended reading:
- F. Rossi, V. Cuomo, C. Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, IV Edizione, Edizioni Minerva Medica
- B.G. Katzung, A.J. Trevor, Farmacologia generale e clinica, X edizione, PICCIN
Reference books:
- A. Goodman & Gilman, Le basi farmacologiche della terapia, XIII edizione, Zanichelli
- F. Clementi, G. Fumagalli, Farmacologia generale e molecolare, V edizione, Edra - Educational objectives
- At the end of the course students will have learned the pharmacodynamics, pharmacokinetics, undesirable side effects, toxicological aspects, the therapeutic foundations and methods of administration of drugs most important in medical practice.
Should be aware of the factors that influence the pharmacological effect and / or therapeutic, as well as the risk / benefit ratio of drug therapy.
Must know how to make a reasoned choice of drugs in relation to different pathological situations. - Prerequisites
- In order to achieve the intended learning outcomes, the student must have a solid background in anatomy, physiology and general pathology. The student must have already passed the other exams considered as preparatory by the Academic Regulations.
- Teaching methods
- lessons face-to-face
Mandatory attendence - Learning verification modality
- Written exam and oral exam
The test focuses globally on the entire program.
The test consists of 62 multiple choice quiz with five possible answers of which only one is correct;
The exam duration time is 1 hour and 15 minutes.
For the evaluation of the test takes into account the following criteria:
- 0.5 points for each correct answer;
- Less than 0.1 points for each wrong answer;
- 0 points for each question not answered;
The written exam is passed if for each test is obtained a score of at least 18/30.
The oral test is mandatory, concerns topics of the entire program and is primarily designed to evaluate the ability to apply their knowledge for the proper use of the drugs in clinical practice.
Final vote accounts for 40% of the vote overall written test and 60% vote of the oral test. - Extended program
- Drugs acting on the central nervous system
General Anesthetics
Anticonvulsants
Drugs for treatment of neurodegenerative diseases
Pharmacology of drugs of abuse
Endocrine Drugs
Thyroid and Antithyroid
Estrogens, progestins, birth control
Androgens and anabolic steroids
Insulin and oral hypoglycemic
Drugs affecting uterine motility
Chemotherapy
General principles
Antibacterial chemotherapy:
Drugs inhibiting cell wall synthesis
Drugs inhibiting protein synthesis
Fluoroquinolones
Sulfonamides and trimethoprim
Metronidazole
Anti-tuberculosis
Antiprotozoal chemotherapy
Antiviral chemotherapy
Antifungal chemotherapy
Antineoplastic chemotherapy
Cognomi M-Z
- CFU
- 3
- Teacher
- Giuseppe Nocentini
- Teachers
- Graziella Migliorati (Codocenza)
- Giuseppe Nocentini
- Hours
- 12.5 ore (Codocenza) - Graziella Migliorati
- 25 ore - Giuseppe Nocentini
- Language of instruction
- Italian
- Contents
- Drugs acting on the central nervous system
Endocrine Drugs
Drugs affecting uterine motility
Chemotherapy - Reference texts
- Reccomended reading:
- F. Rossi, V. Cuomo, C. Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, IV Edizione, Edizioni Minerva Medica
- B.G. Katzung, A.J. Trevor, Farmacologia generale e clinica, X edizione, PICCIN
Reference books:
- A. Goodman & Gilman, Le basi farmacologiche della terapia, XIII edizione, Zanichelli
- F. Clementi, G. Fumagalli, Farmacologia generale e molecolare, V edizione, Edra - Educational objectives
- At the end of the course students will have learned the pharmacodynamics, pharmacokinetics, undesirable side effects, toxicological aspects, the therapeutic foundations and methods of administration of drugs most important in medical practice.
Should be aware of the factors that influence the pharmacological effect and / or therapeutic, as well as the risk / benefit ratio of drug therapy.
Must know how to make a reasoned choice of drugs in relation to different pathological situations. - Prerequisites
- In order to achieve the intended learning outcomes, the student must have a solid background in anatomy, physiology and general pathology. The student must have already passed the other exams considered as preparatory by the Academic Regulations.
- Teaching methods
- lessons face-to-face
Mandatory attendence - Other information
- no further information
- Learning verification modality
- Written exam and oral exam
The test focuses globally on the entire program.
The test consists of 62 multiple choice quiz with five possible answers of which only one is correct;
The exam duration time is 1 hour and 15 minutes.
For the evaluation of the test takes into account the following criteria:
- 0.5 points for each correct answer;
- Less than 0.1 points for each wrong answer;
- 0 points for each question not answered;
The written exam is passed if for each test is obtained a score of at least 18/30.
The oral test is mandatory, concerns topics of the entire program and is primarily designed to evaluate the ability to apply their knowledge for the proper use of the drugs in clinical practice.
Final vote accounts for 40% of the vote overall written test and 60% vote of the oral test. - Extended program
- Drugs acting on the central nervous system
General Anesthetics
Anticonvulsants
Drugs for treatment of neurodegenerative diseases
Pharmacology of drugs of abuse
Endocrine Drugs
Thyroid and Antithyroid
Estrogens, progestins, birth control
Androgens and anabolic steroids
Insulin and oral hypoglycemic
Drugs affecting uterine motility
Chemotherapy
General principles
Antibacterial chemotherapy:
Drugs inhibiting cell wall synthesis
Drugs inhibiting protein synthesis
Fluoroquinolones
Sulfonamides and trimethoprim
Metronidazole
Anti-tuberculosis
Antiprotozoal chemotherapy
Antiviral chemotherapy
Antifungal chemotherapy
Antineoplastic chemotherapy
PHARMACOLOGY - MOD. 6
| Code | GP004580 |
|---|---|
| Location | PERUGIA |
| CFU | 1 |
| Teacher | Graziella Migliorati |
| Learning activities | Affine/integrativa |
| Area | Attività formative affini o integrative |
| Academic discipline | BIO/14 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 1
- Teacher
- Stefano Bruscoli
- Teachers
- Stefano Bruscoli
- Hours
- 12.5 ore - Stefano Bruscoli
- Language of instruction
- Italian
- Contents
- Toxicology Pharmacological trials Gender pharmacology
- Reference texts
- Reccomended reading:
- F. Rossi, V. Cuomo, C. Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, IV Edizione, Edizioni Minerva Medica
- B.G. Katzung, A.J. Trevor, Farmacologia generale e clinica, X edizione, PICCIN
Reference books:
- A. Goodman & Gilman, Le basi farmacologiche della terapia, XIII edizion, Zanichelli
- F. Clementi, G. Fumagalli, Farmacologia generale e molecolare, V edizion, Edra - Educational objectives
- At the end of the course students will have learned the pharmacodynamics, pharmacokinetics, undesirable side effects, toxicological aspects, the therapeutic foundations and methods of administration of drugs most important in medical practice. Should be aware of the factors that influence the pharmacological effect and / or therapeutic, as well as the risk / benefit ratio of drug therapy. Must know how to make a reasoned choice of drugs in relation to different pathological situations.
- Prerequisites
- In order to achieve the intended learning outcomes, the student must have a solid background in anatomy, physiology and general pathology. The student must have already passed the other exams considered as preparatory by the Academic Regulations.
- Teaching methods
- Lessons face-to-face Mandatory attendence
- Other information
- N/A
- Learning verification modality
- Written exam and oral exam
The test focuses globally on the entire program.
The test consists of 62 multiple choice quiz with five possible answers of which only one is correct;
The exam duration time is 1 hour and 15 minutes.
For the evaluation of the test takes into account the following criteria: - 0.5 points for each correct answer;
- Less than 0.1 points for each wrong answer;
- 0 points for each question not answered;
The written exam is passed if for each test is obtained a score of at least 18/30.
The oral test is mandatory, concerns topics of the entire program and is primarily designed to evaluate the ability to apply their knowledge for the proper use of the drugs in clinical practice.
Final vote accounts for 40% of the vote overall written test and 60% vote of the oral test. - Extended program
- Toxicology
Principles of Toxicology
Mechanisms of toxicity
Fetotoxicity
Abuse, Drug Addiction
Rational basis of treatment of drug addiction Pharmacological trials, pharmacovigilance Gender pharmacology
Cognomi M-Z
- CFU
- 1
- Teacher
- Simona Ronchetti
- Teachers
- Simona Ronchetti
- Hours
- 12.5 ore - Simona Ronchetti