Unit SYSTEMIC PATHOLOGY V
- Course
- Medicine and surgery
- Study-unit Code
- GP004561
- Location
- PERUGIA
- Curriculum
- In all curricula
- Teacher
- Roberto Gerli
- CFU
- 12
- Course Regulation
- Coorte 2018
- Offered
- 2021/22
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa integrata
BLOOD DISEASES - MOD. 1
| Code | GP004621 |
|---|---|
| Location | PERUGIA |
| CFU | 2 |
| Teacher | Brunangelo Falini |
| Teachers |
|
| Hours |
|
| Learning activities | Caratterizzante |
| Area | Fisiopatologia, metodologia clinica, propedeutica clinica e sistematica medico-chirurgica |
| Academic discipline | MED/15 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian |
| Contents | MALATTIE DEL SANGUE |
| Reference texts | Harrison's - Principles of Internal Medicine Hoffbrand/Moss - Essential Haematology Bosi, De Stefano, Di Raimondo, La Nasa - Manuale di Malattie del sangue Avvisati - Ematologia di Mandelli Hoffman - Hematology basic priniples and practice |
| Educational objectives | L'obiettivo generale dell'insegnamento consiste nel fornire agli studenti le basi per affrontare lo studio delle malattie del sangue sia oncoematologiche che non. |
| Prerequisites | Al fine di comprendere e saper affrontare il corso lo studente deve possedere le nozioni generali relative a: - fisiologia del sangue, caratteristiche e funzioni degli elementi del sangue: leucociti, eritrociti e piastrine - anatomia, organizzazione e funzioni del sistema linfatico - immunità cellulare e umorale - struttura del midollo osseo e emopoiesi - l’esame emocromocitometrico |
| Teaching methods | Lezioni frontali in aula sui principali argomenti del corso - Discussione casi clinici a completamento dei principali argomenti trattati |
| Learning verification modality | La modalità di valutazione prevede una prova orale mediante la quale verranno valutate le conoscenze acquisite e la capacità dello studente di comunicare e ragionare di fronte ad un quesito specifico. |
| Extended program | Leucemia mieloide cronica - Mielofibrosi idiopatica - Policitemia vera - Trombocitemia essenziale LE SINDROMI MIELODISPLASTICHE LE LEUCEMIE ACUTE - Leucemie acute mieloidi e linfoidi - Classificazione e presentazione clinica - Principali alterazioni molecoalri asssociate - Esempi di terapia "target" PATOLOGIE LINFOPROLIFERATIVE CRONICHE - La leucemia linfatica cronica - La leucemia a cellule capellute I LINFOMI MALIGNI - Morbo di Hodgkin - Linfomi non Hodgkin LE GAMMOPATIE MONOCLONALI - MGUS - Mieloma Multiplo - Macroglobulinemia di Waldenstrom CENNI DI TERAPIA TRASFUSIIONALE - Componenti del sangue o terapia con i componenti del sangue |
BLOOD DISEASES - MOD. 2
| Code | GP004622 |
|---|---|
| Location | PERUGIA |
| CFU | 1 |
| Teacher | Maria Paola Martelli |
| Teachers |
|
| Hours |
|
| Learning activities | Caratterizzante |
| Area | Fisiopatologia, metodologia clinica, propedeutica clinica e sistematica medico-chirurgica |
| Academic discipline | MED/15 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian |
| Contents | The anemias: - General aspects of anemia and erythropoiesis - Classification of anemia: a. etiopathogenetic; b. morphological - Morphological alterations of red blood cells. The smear of peripheral venous blood - Iron deficiency anemia - Megaloblastic Anemia and other macrocytic anemias - Anemia of chronic disorders - Hemolytic anemias Hemolytic hereditary disorders Extraglobular causes of hemolytic disorders - Thalassemias - Aplastic anemia and other selective cytopenias (erythroblastopenia isolated, neutropenia and thrombocytopenia) - Differential diagnosis of anemic syndromes. Discussion of clinical cases and diagnostic work. The thrombocytopenia. - Idiopathic Thrombocytopenia Purpura - Thrombotic thrombocytopenia purpura Issues of general haematological interest: - Numerical changes of blood elements: a. differential diagnosis of erythrocytosis b. leukopenia and leukocytosis (lymphopenia and lymphocytosis, neutropenia and neutrophilia) c. thrombocytopenia and thrombocytosis - Splenomegaly. - Splenectomy. Indications in hematology and complications - Lymphadenopathy: Differential Diagnosis - Hematological alterations in systemic diseases |
| Reference texts | Harrison's - Principles of Internal Medicine Hoffbrand/Moss - Essential Haematology Bosi, De Stefano, Di Raimondo, La Nasa – Manuale di Malattie del Sangue Avvisati – Ematologia di Mandelli Hoffman - Hematology basic principles and practice |
| Educational objectives | The learning outcomes are compliant with the provisions in the didactic published at: http: //www.med.unipg.it/ccl (http://www.med.unipg.it/ccl) In detail, the general objective of education is to provide students with the foundation to address the study of blood diseases (either malignant or not). |
| Prerequisites | In order to understand and know how to tackle the course, students must have the basic understanding on: - Physiology of blood, features and functions of the elements of blood (leukocytes, erythrocytes and platelets) - Anatomy, organization and functions of the lymphatic system - Cellular and humoral immunity - Structure of the bone marrow and hematopoiesis - The blood count - Principles of Serum protein electrophoresis - The monoclonal antibodies |
| Teaching methods | Face to face lessons. Clinical cases discussion. |
| Learning verification modality | Through oral test (lasting about 15-20 minutes) will be assessed the acquired knowledge and the student's ability to communicate and reason confronted with a specific question. The oral exam consists of a discussion-interview on the topics covered during the course or at least in the program and in-depth texts Recommended. For Blood Diseases Teaching a topic of oncohematology and non malignant disease will be addressed. |
| Extended program | The anemias: - General aspects of anemia and erythropoiesis - Classification of anemia: a. etiopathogenetic; b. morphological - Morphological alterations of red blood cells. The smear of peripheral venous blood - Iron deficiency anemia - Megaloblastic Anemia and other macrocytic anemias - Anemia of chronic disorders - Hemolytic anemias Hemolytic hereditary disorders Extraglobular causes of hemolytic disorders - Thalassemias - Aplastic anemia and other selective cytopenias (erythroblastopenia isolated, neutropenia and thrombocytopenia) - Differential diagnosis of anemic syndromes. Discussion of clinical cases and diagnostic work. The thrombocytopenia. - Idiopathic Thrombocytopenia Purpura - Thrombotic thrombocytopenia purpura Issues of general haematological interest: - Numerical changes of blood elements: a. differential diagnosis of erythrocytosis b. leukopenia and leukocytosis (lymphopenia and lymphocytosis, neutropenia and neutrophilia) c. thrombocytopenia and thrombocytosis - Splenomegaly. - Splenectomy. Indications in hematology and complications - Lymphadenopathy: Differential Diagnosis - Hematological alterations in systemic diseases |
DISEASES OF THE IMMUNE SYSTEM
| Code | GP005656 |
|---|---|
| Location | PERUGIA |
| CFU | 2 |
| Teacher | Andrea Velardi |
| Teachers |
|
| Hours |
|
| Learning activities | Caratterizzante |
| Area | Medicina delle attività motorie e del benessere |
| Academic discipline | MED/09 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian |
| Contents | Immunodeficiencies: pathogenic mechanisms and risk nfettivo diagnosis of primary immunodeficienze.Immunodeficienze; Severe Combined Immunodeficiency; Immunodeficiency by defective granulocyte function; immunideficienze The secondary; Secondary immunodeficiencies (not AIDS); After splenectomy Immediate hypersensitivity diseases, autoimmune diseases; Immune diseases (vasculitis); immunopathogenesis and clinical; The systemic vasculitinecrotizzanti; immunopathogenesis and clinical; Systemic autoimmune diseases; immunopathogenesis and clinical |
| Reference texts | HARRISON " Principles of Internal Medicine" |
| Educational objectives | At the end of the course the student will have to be able to know and to frame, from a clinical and diagnostic point of view , the main diseases of the immunity system., pimary and secondary systemic autoimmunities and immunodeficiency. The verification of the real acquisizioneis of the student will be carried out during examination. |
| Prerequisites | In order to start Diseases of the Immune System lessons, the student should have good knowledge of anatomy and physiopatology and good skill in general phisical examonation of the patient. |
| Teaching methods | the course is organized in the following way: lecture on all subjects of the course practices that the students, divided in small groups, they will hold both in ambulatory that in department |
| Learning verification modality | The exam includes a multiple choice written test (30 questions with up to 5 possible answers of which only 1 correct). Score: + 1 for correct answer, - 0.25 for wrong answer, 0 points for not done answer. Questions will cover all rheumatology topics and can be afforded with a basic knowledge of such topics. The oral exam is open to students who passed the first written test (with a score of at least 18/30) and includes wider questions aimed at evaluating theoretical and practical skills as well as deductive processes and communication. The average examination time is 20-25 minutes. |
| Extended program | Immunodeficiencies: pathogenic mechanisms and risk nfettivo diagnosis of immunodeficiencies. Primary immunodeficiencies: Antibody deficiency diseases: X-linked agammaglobulinemia, Camune Variable immunodeficiency, IgA deficiency. Severe Combined Immunodeficiency: Interleukin receptor gamma chain deficiency, recombinase activating gene deficiency. Immunodeficiencies deficit granulocyte function: Chronic Granulomatous Disease The immunideficienze secondary AIDS: immunopatogeensi, natural history of the disease, the main clinical features. Secondary immunodeficiencies (not AIDS): after splenectomy In the course of lymphoproliferative disorders In the course of immunosuppressive and cytostatic After transplantation of hematopoietic cells, etc.. Immediate hypersensitivity diseases: Urticaria and angioedema, food Allergies Allergic rhinitis, Asthma. Autoimmune diseases: Immunological pathogenesis of organ-specific autoimmune diseases principalei: Hashimoto's thyroiditis, diabetes mellitus, multiple sclerosis, aplastic anemia, and autoimmune pistrinipenie, etc.. Immune diseases (vasculitis): immunopathogenesis and clinical pictures: From genes Infected: Schonlein-Henoch purpura, hepatitis .. The malettia serum drug and vasculitis. Sindromei clinical immune complex amlattie associated with systemic autoimmune (SLE, RA etc;) with cancer. the crioglobulinemie The systemic vasculitinecrotizzanti: immunopathogenesis and clinical pictures: Panarteritis Gnarled, microscipica polyangiitis, Churg-Strauss disease Wegener's granulomatosis Aterite time Disease Behce Systemic autoimmune diseases: immunopathogenesis and clinical Systemic lupus erythematosus Scleroderma and overlap syndromes sarcoidosis |
MOLECULAR MEDICINE
| Code | GP004623 |
|---|---|
| Location | PERUGIA |
| CFU | 1 |
| Teacher | Cristina Mecucci |
| Teachers |
|
| Hours |
|
| Learning activities | Caratterizzante |
| Area | Fisiopatologia, metodologia clinica, propedeutica clinica e sistematica medico-chirurgica |
| Academic discipline | MED/15 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian |
| Contents | Technological approaches for the study of the genome. Leukemic and tumor stem cells, multistep process of oncogenesis, mechanisms of alteration of oncogenes, tumor suppressors, shelter genes and check-point genes. Models of pathogenesis of congenital and acquired medullary insufficiencies. Models of pathogenesis of Acute Leukemia. Tyrosinchinase. Pathogenesis models of lymphoproliferative disorders. Myeloma pathogenesis models. Models of pathogenesis of solid tumors (lung, breast, colon). |
| Reference texts | The material will be provided by professor |
| Teaching methods | Frontal lessons Seminars |
| Learning verification modality | Multiple choice quiz or oral exam |
| Extended program | Technological approaches for the study of the genome. Leukemic and tumor stem cells, multistep process of oncogenesis, mechanisms of alteration of oncogenes, tumor suppressors, shelter genes and check-point genes. Models of pathogenesis of congenital and acquired medullary insufficiencies. Models of pathogenesis of Acute Leukemia. Tyrosinchinase. Pathogenesis models of lymphoproliferative disorders. Myeloma pathogenesis models. Models of pathogenesis of solid tumors (lung, breast, colon). |
REUMATHOLOGY
| Code | GP005657 |
|---|---|
| Location | PERUGIA |
| CFU | 2 |
| Teacher | Roberto Gerli |
| Teachers |
|
| Hours |
|
| Learning activities | Caratterizzante |
| Area | Clinica delle specialità medico-chirurgiche |
| Academic discipline | MED/16 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | ITALIAN |
| Contents | Classification, epidemiology and pathogenesis of rheumatic disease. Clinical features of most common acute and chronic osteoarticular disease, inflammatory and not, of extra-articular rheumatism, of systemic autoimmunitary disease and of systemic vasculitides. |
| Reference texts | REUMATOLOGIA per studenti e Medici di a cura di UNIREUMA. IDELSON GNOCCHI IV Ed. 2022. HARRISON et al. Principles of Internal Medicine XX Ed. McGraw Hill Ed. |
| Educational objectives | At the end of the Course students are expected to recognize and define the peculiar features of most common chronic articular conditions, both inflammatory and degenerative, extra-articular rheumatic diseases, systemic autoimmune diseases and systemic vasculitis, from an etiologic, pathogenic and, most importantly, clinical point of view. In addition, the students are asked to prove the ability to recognize and interpret the laboratory tests specific for the aforementioned conditions and the most common instrumental procedures employed in rheumatology clinics. The students’ diagnostic approach based on signs and symptoms will also be evaluated. |
| Prerequisites | In order to start Rheumatology lessons, the student should have good knowledge of anatomy and physiopathology and good skill in general phisical examination of the patient. |
| Teaching methods | The Course includes 25 hours with 14 theoretical hours and 11 hours of practical skills and practical training or seminars. |
| Other information | |
| Learning verification modality | The exam includes a multiple choice written test (30 questions with up to 5 possible answers of which only 1 correct). Score: + 1 for correct answer, - 0.25 for wrong answer, 0 points for not done answer. Questions will cover all rheumatology topics and can be afforded with a basic knowledge of such topics. The test will be performed only if the pandemic risk will allow it. The oral exam is open to students who passed the first written test (with a score of at least 18/30) and includes wider questions aimed at evaluating theoretical and practical skills as well as deductive processes and communication. The average examination time is 20-25 minutes. |
| Extended program | 1. Definition, classification and epidemiology of rheumatic diseases 2. The musculoskeletal system: anatomic- functional elements (signs) 3. Etiopathogenetic mechanism of rheumatic diseases 4. Signs and syntoms of rheumatic diseases 5. Laboratory and imaging diagnosis and synovial liquid analysis 6. Articular inflammatory reumatism i. Rheumatoid arthritis and other arthritis ii. Spondyloarthropathies (overview) iii. Ankylosing Spondylitis iv. Reactive arthritis v. Psoriatic arthritis vi. Enteropathic arthropaties 7. Connective tissue disease i. Systemic Lupus erythematosus ii. Antiphospholipid syndrome iii. Systemic Sclerosis iv. Polymyositis/ Dermatomyositis v. Sjögren syndrome vi. Overlap syndrome vii. Undifferentiated connective tissue diseases (UCTD) 8. Primitive systemic vasculitides i. Large sized-arteries: Takayasu arteritis, temporal arteritis ii. Medium -sized arteries: polyarteritis nodosa iii. Medium and small-sized arteries ANCA-associated ( Wegener's granulomatosis, Churg-Strauss syndrome, micropolyangiitis) iv. Small- sized arteries (Schönlein-Henoch purpura, cryoglobulinemia) 9. Secondary systemic vasculitides 10. Behçet's syndrome 11. Polymyalgia rheumatica 12. Septic and post-infective arthritis (rheumatic fever) 13. Microcrystal arthropaties (Gout, Calcium pyrophosphate dihydrate and hydroxyapatite deposition disorders) 14. Osteoarthrosis 15. Localized extra-articular rheumatic diseases and fibromyalgia 16. Neurovascular and neurologic syndrome i. Algodystrophi syndrome ii. Raynaud 's phenomenon 17. Miscellaneous disorders associated with articular manifestations i. Sarcoidosis ii. Amyloidosis |
PROFESSIONALISING TRAINING IN BLOOD DISEASES
| Code | GP004624 |
|---|---|
| Location | PERUGIA |
| CFU | 1 |
| Teacher | Roberto Gerli |
| Learning activities | Altro |
| Area | Tirocini formativi e di orientamento |
| Academic discipline | MED/15 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 1
- Teacher
- Brunangelo Falini
- Teachers
- Brunangelo Falini
- Hours
- 25 ore - Brunangelo Falini
Cognomi M-Z
- CFU
- 1
- Teacher
- Maria Paola Martelli
- Teachers
- Maria Paola Martelli
- Hours
- 25 ore - Maria Paola Martelli
- Language of instruction
- Italian
- Contents
- Activities in the outpatient and clinic department with the specialist:
General approach to the patient with alteration of CBC
Discussion of normal and abnormal blood counts:
anemia and erythrocytosis
leucopenie and leukocytosis
thrombocytopenia and thrombocytosis
pancytopenia
General approach to the patient with lymphadenopathy
General approach to the patient with splenomegaly
- Execution, staining and reading the smear of peripheral venous blood (SVP)
- Vision and participation in the examination of the bone marrow: bone marrow aspiration and biopsy procedures - Reference texts
- Harrison's - Principles of Internal Medicine
Hoffbrand/Moss - Essential Haematology
Bosi, De Stefano, Di Raimondo, La Nasa – Manuale di Malattie del Sangue
Avvisati – Ematologia di Mandelli
Hoffman - Hematology basic principles and practice - Educational objectives
- The learning outcomes are compliant with the provisions in the didactic published at: http: //www.med.unipg.it/ccl (http://www.med.unipg.it/ccl)
In detail, the general objective of education is to provide students with the foundation to address the study of blood diseases (either malignant or not).
The main skills that will be acquired:
- Analyze a CBC
- Identify the diagnostic procedure for alterations in the numbers of blood elements
- Identify the diagnostic procedure in case of lymphadenopathy
- Identify the diagnostic procedure in case of splenomegaly - Prerequisites
- Blood Diseases course attendance
- Teaching methods
- Clinic department and laboratory attendance
- Other information
- Hematology Department / Day Hospital - Santa Maria della Misericordia Hospital –Perugia
- Learning verification modality
- Clinical case discussion. Practice test in the department
- Extended program
- Activities in the outpatient and clinic department with the specialist:
General approach to the patient with alteration of CBC
Discussion of normal and abnormal blood counts:
anemia and erythrocytosis
leucopenie and leukocytosis
thrombocytopenia and thrombocytosis
pancytopenia
General approach to the patient with lymphadenopathy
General approach to the patient with splenomegaly
- Execution, staining and reading the smear of peripheral venous blood (SVP)
- Vision and participation in the examination of the bone marrow: bone marrow aspiration and biopsy procedures
PROFESSIONALISING TRAINING IN DISEASES OF THE IMMUNE SYSTEM
| Code | GP005658 |
|---|---|
| Location | PERUGIA |
| CFU | 1 |
| Teacher | Andrea Velardi |
| Learning activities | Altro |
| Area | Tirocini formativi e di orientamento |
| Academic discipline | MED/09 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 1
- Teacher
- Andrea Velardi
- Teachers
- Antonio Pierini (Codocenza)
- Hours
- 25 ore (Codocenza) - Antonio Pierini
- Language of instruction
- Italian
- Contents
- Tirocinio professionalizzante di malattie del sistema immunitario
- Reference texts
- HARRISON "TRATTATO DI MEDICINA INTERNA"
- Educational objectives
- I risultati dell'apprendimento si basano sulla verifica di abilità acquisite, sulla verifica delle conoscenze da un punto di vista clinico e diagnostico delle principali complicanze infettive causate da stati di Immunodeficienze.
- Prerequisites
- Al fine di comprendere con profitto gli argomenti inclusi nel programma di torocinio, è indispensabile che lo studente abbia sostenuto con successo gli esami di fisiologia e patologia generale.
- Teaching methods
- Partecipazione alle attività di reparto
- Learning verification modality
- Prova orale
- Extended program
- Il programma di tirocinio prevede la partecipazione all'attività clinica, con lo specialista, nel reparto di trapianto di midollo allogenico, e consente di avere una quasi completa visione di complicanze infettive causate da stati di Immunodeficienze
Cognomi M-Z
- CFU
- 1
- Teacher
- Andrea Velardi
- Teachers
- Antonio Pierini (Codocenza)
- Hours
- 25 ore (Codocenza) - Antonio Pierini
- Language of instruction
- Italian
- Contents
- Tirocinio professionalizzante di malattie del sistema immunitario
- Reference texts
- HARRISON "TRATTATO DI MEDICINA INTERNA"
- Educational objectives
- I risultati dell'apprendimento si basano sulla verifica di abilità acquisite, sulla verifica delle conoscenze da un punto di vista clinico e diagnostico delle principali complicanze infettive causate da stati di Immunodeficienze.
- Prerequisites
- Al fine di comprendere con profitto gli argomenti inclusi nel programma di torocinio, è indispensabile che lo studente abbia sostenuto con successo gli esami di fisiologia e patologia generale.
- Teaching methods
- Partecipazione alle attività di reparto
- Learning verification modality
- Prova orale
- Extended program
- Il programma di tirocinio prevede la partecipazione all'attività clinica, con lo specialista, nel reparto di trapianto di midollo allogenico, e consente di avere una quasi completa visione di complicanze infettive causate da stati di Immunodeficienze
PROFESSIONALISING TRAINING IN MOLECULAR MEDICINE
| Code | GP004625 |
|---|---|
| Location | PERUGIA |
| CFU | 1 |
| Teacher | Cristina Mecucci |
| Learning activities | Altro |
| Area | Tirocini formativi e di orientamento |
| Academic discipline | MED/15 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 1
- Teacher
- Cristina Mecucci
- Teachers
- Cristina Mecucci
- Hours
- 25 ore - Cristina Mecucci
- Language of instruction
- Italian
- Contents
- Technological approaches to genome surveys. Protocols and their applications.
- Educational objectives
- Ability to address diagnostic investigations and optimize procedures.
- Prerequisites
- Knowledge of the genetic basis of tumors.
- Teaching methods
- Tutor system in working groups.
- Learning verification modality
- During the exam
- Extended program
- Conventional cytogenetics. FISH, PCR, sequencing. Telomeres, Chromosomal instability test. Test on paraffin sections. Nucleic acids, separation. Microarrays.
Cognomi M-Z
- CFU
- 1
- Teacher
- Cristina Mecucci
- Teachers
- Cristina Mecucci
- Hours
- 25 ore - Cristina Mecucci
- Language of instruction
- Italian
- Contents
- Technological approaches to genome surveys. Protocols and their applications.
- Educational objectives
- Ability to address diagnostic investigations and optimize procedures.
- Prerequisites
- Knowledge of the genetic basis of tumors.
- Teaching methods
- Tutor system in working groups.
- Learning verification modality
- during the exam
- Extended program
- Conventional cytogenetics. FISH, PCR, sequencing. Telomeres, Chromosomal instability test. Test on paraffin sections. Nucleic acids, separation. Microarrays.
PROFESSIONALISING TRAINING IN REUMATHOLOGY
| Code | GP005659 |
|---|---|
| Location | PERUGIA |
| CFU | 1 |
| Teacher | Roberto Gerli |
| Learning activities | Altro |
| Area | Tirocini formativi e di orientamento |
| Academic discipline | MED/16 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 1
- Teacher
- Roberto Gerli
- Teachers
- Roberto Gerli
- Hours
- 25 ore - Roberto Gerli
- Language of instruction
- Italian
- Contents
- Clinical activity with Rheumatologist, included clinical history, physical examination, diagnosis and therapeutic intervention; infusion of biotechnological agents; instrumental diagnosis by ultrasound evaluation of muscle-skeletal areas and ultrasound-driven interventions for joints, tendons, ...; diagnosis of microcirculation disorders by videocapillaroscopic examination; evaluations of foot and posture disorders.
- Reference texts
- REUMATOLOGIA per studenti e Medici a cura di UNIREUMA. IDELSON GNOCCHI IV Ed. 2022.
HARRISON et al. Principles of Internal Medicine XX Ed.
McGraw Hill Ed. - Educational objectives
- Results based on check of the acquired ability, behavior and interaction degree of the student.
- Prerequisites
- For the purpose of learning, the student should have good knowledge of anatomy and physiopathology and good skill in general phisical examination of the patient.
- Teaching methods
- Partecipation to the above described activities
- Learning verification modality
- For the professionalizing intership, there is no a specific exam, but this included in the final oral exam.
- Extended program
- 1. Definition, classification and epidemiology of rheumatic diseases
2. The musculoskeletal system: anatomic- functional elements (signs)
3. Etiopathogenetic mechanism of rheumatic diseases
4. Signs and syntoms of rheumatic diseases
5. Laboratory and imaging diagnosis and synovial liquid analysis
6. Articular inflammatory reumatism
i. Rheumatoid arthritis and other arthritis
ii. Spondyloarthropathies (overview)
iii. Ankylosing Spondylitis
iv. Reactive arthritis
v. Psoriatic arthritis
vi. Enteropathic arthropaties
7. Connective tissue disease
i. Systemic Lupus erythematosus
ii. Antiphospholipid syndrome
iii. Systemic Sclerosis
iv. Polymyositis/ Dermatomyositis
v. Sjögren syndrome
vi. Overlap syndrome
vii. Undifferentiated connective tissue diseases (UCTD)
8. Primitive systemic vasculitides
i. Large sized-arteries: Takayasu arteritis, temporal arteritis
ii. Medium -sized arteries: polyarteritis nodosa
iii. Medium and small-sized arteries ANCA-associated ( Wegener's granulomatosis, Churg-Strauss syndrome, micropolyangiitis)
iv. Small- sized arteries (Schönlein-Henoch purpura, cryoglobulinemia)
9. Secondary systemic vasculitides
10. Behçet's syndrome
11. Polymyalgia rheumatica
12. Septic and post-infective arthritis (rheumatic fever)
13. Microcrystal arthropaties (Gout, Calcium pyrophosphate dihydrate and hydroxyapatite deposition disorders)
14. Osteoarthrosis
15. Localized extra-articular rheumatic diseases and fibromyalgia
16. Neurovascular and neurologic syndrome
i. Algodystrophi syndrome
ii. Raynaud 's phenomenon
17. Miscellaneous disorders associated with articular manifestations
i. Sarcoidosis
ii. Amyloidosis
Cognomi M-Z
- CFU
- 1
- Teacher
- Roberto Gerli
- Teachers
- Carlo Perricone (Codocenza)
- Hours
- 25 ore (Codocenza) - Carlo Perricone