Unit VETERINARY MOLECULAR GENETICS
- Course
- Medical, veterinary and forensic biotechnological sciences
- Study-unit Code
- A001781
- Curriculum
- Veterinario
- Teacher
- Stefano Capomaccio
- Teachers
-
- Stefano Capomaccio
- Hours
- 52 ore - Stefano Capomaccio
- CFU
- 6
- Course Regulation
- Coorte 2020
- Offered
- 2021/22
- Learning activities
- Caratterizzante
- Area
- Discipline veterinarie e riproduzione animale
- Academic discipline
- AGR/17
- Type of study-unit
- Opzionale (Optional)
- Type of learning activities
- Attività formativa monodisciplinare
- Language of instruction
- Italian / English
- Contents
- Reference texts
- Personal notes and Keynotes from the teacher available in Unistudium.
As optional reference material (student choice): Genomi 4 "T.A. Brown", Edises.
Genetica Animale, Applicazioni Zootecniche e Veterinarie "G. Pagnacco" Casa Editrice Ambrosiana. - Educational objectives
- The course will illustrate and review some concepts of molecular genetics and the main applications to animals of veterinary interest.
The achievement of independence by the student in the understanding and implementation of experimental designs aimed at evaluating genetic differences between populations and the realization of molecular tests to be applied in laboratory contexts is proposed as a main learning result.
The main skills achieved will be: knowledge of the necessary tools to carry out molecular diagnosis and the prevention of genetic diseases; genetic-molecular evaluation of traits of interest in animal populations; interpretation of the results of a possible genetic-molecular test performed by another laboratory or competent structure; experimental designs’ planning for studying and understanding complex traits. - Prerequisites
- Background on genetics and molecular genetics as well as in bioinformatics are desirable but not mandatory.
- Teaching methods
- Lectures and laboratory exercises (WET and DRY LAB)
- Other information
- Learning verification modality
- Evaluation is carried out through an oral exam. A typical exam consists in a 30 minutes interview aiming to assess knowledge level and understanding capabilities on theoretical and methodological contents acquired by the student. The oral exam will also test the student communication skills, lexical congruence and consistency when presenting enquired topics.
- Extended program
- Genome organization and functioning: functional units in complex genomes, transcription and gene expression, mobile genetic elements, epigenetic signals;
Recombinant DNA: manipulation of genetic material, mapping (genetic and physical maps), molecular markers;
New data: Next generation sequencing, assembly of contiguous DNA sequences, interpretation of a genomic sequence; SNP chips and their applications. Genotyping by sequencing.
Genes controlling hereditary diseases and their molecular diagnosis.
Analysis of molecular data: biological databases, sequence alignments, GWAS, primer design, molecular testing in silico.