Medical, veterinary and forensic biotechnological sciences
Study-unit Code
In all curricula
Paolo Gresele
  • Paolo Gresele
  • Loredana Bury (Codocenza)
  • 33 ore - Paolo Gresele
  • 19 ore (Codocenza) - Loredana Bury
Course Regulation
Coorte 2021
Learning activities
Discipline di base applicate alle biotecnologie
Academic discipline
Type of study-unit
Obbligatorio (Required)
Type of learning activities
Attività formativa monodisciplinare
Language of instruction
Coagulation, Approach to the patient with hemorrhagic diathesis, Diagnostic tests, Flow cytometry applied to the study of hemostasis, Megakaryocytes and platelet formation, Cellular models for the study of inherited platelet disorders, Laboratory monitoring of antithrombotic drugs, Micro-RNA in hemostasis and thrombosis, DVT and thrombophilia, PCR, Real Time PCR and sequencing applied to hematoma and thrombosis pathologies, Interaction between dyslipidemia and hemostasis and thrombosis, autoimmune thrombocytopenias and platelet function disorders, Congenital hemorrhagic diseases and acquired coagulopathies, Animals models for the study of hemostasis, thrombosis and atherosclerosis, Methods for the study of endothelial cells.
Reference texts
The teacher will prepare the didactic materials on the basis of the scientific literature available on the specific topics. Accordingly, participation to the teacher's lessons is essential. On specific topics, references to specific articles or textbooks will be provided.
Educational objectives
The course aims to provide students with the basic knowledge on the diagnostic and therapeutic techniques the most update biotechnological method in the field of hemostasis and thrombosis.
General biology, animal and vegetal models for biotecnology, molecular biology, principles of general anatomy and physiology, pharmacology
Teaching methods
Didactic activity will be mainly focused on face-to-face lessons using Power Point slides, practical lessons will be made at the Hemostasis and Thrombosis Centre.
Other information
The attendance to at least 80% of the lessons is required in order to allow a good understanding of the arguments in the absence of a single reference textbook. Materials presented during classes will be made available after the lessons.
Learning verification modality
Multiple choice and free text, written assessment
Extended program
The hemostatic process: physiolpathology and clinical aspects.Approach to the patient with suspected hemorrhagic disorders. Main diseases in the field of hemostasis and thrombosis (genetic and acquired hemorrhagic disorders);Megacaryocytes and piastrinopoiesis. Cellular models for the study of inherited platelet disorders. Flow cytometry applied to the study of hemostasis. Diagnostic tests for platelet disorders. Venous thromboembolism and the study of congenital and acquired thrombophilia. MicroRNA in hemostasis and thrombosis. Molecular biology techniques applied to hemostasis and thrombosis. Animal models in biomedical research in the held of hemostasis, thrombosis and atheroclerosis. Immunologic thrombocytopenias. Laboratory monitoring of antithrombotic drugs. Methos for the suty of endothelial cells- Interaction between lipids and hemostatic system
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