| Code |
GP003955 |
| CFU |
2 |
| Teacher |
Letizia Mezzasoma |
| Teachers |
|
| Hours |
- 30 ore - Letizia Mezzasoma
|
| Learning activities |
Base |
| Area |
Scienze biomediche |
| Academic discipline |
BIO/13 |
| Type of study-unit |
Obbligatorio (Required) |
| Language of instruction |
Italian |
| Contents |
Characteristics of living organisms. Prokaryotic and eukaryotic cells.
Structure and function of cell membrane and cellular organelles. Genome organization. Gene expression and its regulation. DNA duplication and reparation. Mutations. Cell cycle and its control. General genetics.
|
| Reference texts |
Roberti, GA. Bistocchi, C. Antognelli, VN. Talesa: "Biochimica e Bilogia pr le professioni santarie". McGrawHill. G.
Sadava D. Hills DM, Craig Heller H, Berembaum MR. Elementi di biologia e Genetica. Zanichelli.
|
| Educational objectives |
Objective of the course is the integrated study of the cell and living organisms, with particular reference to the mechanisms involved in the biogenesis of membranes, organelles and cellular structures, interactions among cells and interactions between cells and extracellular environment, duplication and transmission of genetic information, cell cycle and its control. Human genetics
|
| Prerequisites |
In order to understand the contents of the teaching course, it is fundamental to have acquired the basic knowledge of chemistry and biology according to the programs carried out at the High Schools. In particular, for the understanding of the language used in Biology, the student must have a general knowledge of the cellular structure , the structure of atoms, chemical bonds and of simple inorganic and organic molecules.
|
| Teaching methods |
Face to face
|
| Other information |
The teaching activities, as well as the schedule of lessons and exams will be published on the web site of the Degree Course.
|
| Learning verification modality |
The exam will be an oral examination that will consist of a discussion no longer than 20 minutes, aimed at ascertaining the level of knowledge and the understanding reached by the student and the ability of the student to integrate and connect the teaching contents. The oral examination will also test the student’s ability of communication and of an autonomous exposure.
|
| Extended program |
The biological organization. Characteristics of living organisms. Prokaryotic and eukaryotic cells. Virus.Biological macromolecules: proteins, nucleic acids, lipids, carbohydrates. The cell membrane: structure and function with particular reference to transport mechanisms and cellular communication. The nucleus and nucleolus: structure and function. Organization of chromatin, chromosomes. Characteristics of the eukaryotic gene. Gene expression: transcription and its regulation. Editing of primary transcripts. Gene expression: Characteristics of the genetic code and its operation. Translation and its control. Smooth and rough endoplasmic reticulum. Golgi apparatus, lysosomes and peroxisomes. Vesicle trafficking and sorting of proteins. The mitochondria and cellular respiration. Cytoskeleton.Cell cycle and its control. Interphase, DNA replication, mitosis. Mutations. Reproduction of multicellular organisms: Meiosis and gametogenesis. Definitions and meaning of a gene locus, allele, haploid, diploid genotype, phenotype, homozygous, heterozygous, dominant and recessive. Mendel's laws and their interpretation. Extensions to Mendelian analysis. Normal and pathological human karyotype. ABO and Rh blood type.
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