Unit ADVANCED MOLECULAR BIOLOGY

Course
Biology
Study-unit Code
GP004083
Curriculum
Biomolecolare
Teacher
Sabata Martino
Teachers
  • Sabata Martino
Hours
  • 47 ore - Sabata Martino
CFU
6
Course Regulation
Coorte 2020
Offered
2020/21
Learning activities
Caratterizzante
Area
Discipline del settore nutrizionistico e delle altre applicazioni
Academic discipline
BIO/13
Type of study-unit
Obbligatorio (Required)
Type of learning activities
Attività formativa monodisciplinare
Language of instruction
Italian
Contents
Biological relevance of the basic biological molecular mechanisms
Advancing applications in the biomedical, nutrition and environment fields.
Molecular mechanisms of stem cell biology.
Regulation of gene expression
Apoptosis
Aging mechanisms
Reference texts
Educational slides provided by the teacher
LEWIN Benjamin IL GENE X
Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monthy Krieger, Matthew P. Scott, Antony Bretscher, Hidde Ploegh, Paul Matsudaira Molecular cell biology
James D. Watson, Tania A. Baker, Stephen P. Bell, Alexander Gann, Michael Levine, Richard Losick
ed, Molecular biology of the gene .
Helen Kreuzer, Adrianne Massey Molecular Biology and Biotechnology
Educational objectives
Mechanisms of regulation of gene expression. Relevance of molecular mechanisms of animal and plant biology. Molecular mechanisms of stem cell biolog
Prerequisites
Molecular Biology, Biochemistry
ChemistryùCellular Biology
Teaching methods
Lectures will be made by using slides and movies. Some lessons could be dedicated to innovative issues also proposed by students, with the involvement of students themselves.
Practical lessons (1 CFU) will be held in the laboratory and will focus on basic methodologies such as transfection of nucleic acids on host cells and analysis of recombinant proteins by immunofluorence.
Other information
It is planned a tutorial activity during the course and for students who request help for the preparation of the exam. The dates of receipt students are available in the professor's website.
Learning verification modality
Oral exam
Extended program
Regulation of gene expression: mechanisms of gene activation and repression.
MicroRNA; Long non-coding-RNA; CE-RNA. Mechanism of gene repragramming .
Molecular mechanism of cell cycle. Apoptosis. Molecular mechanism of Aging .
Stem cells and regulatory mechanism. Stem cell: therapeutic applications. Induced pluripoten stem cells. Gene therapy.
Interactions between macromolecules: mechanisms and biological significance.
Molecular Basicmechanisms as substrate for the development of biotechnologies.
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