Unit MICROBIOLOGY

Course
Pharmacy
Study-unit Code
65010709
Location
PERUGIA
Curriculum
In all curricula
Teacher
Anna Vecchiarelli
Teachers
  • Anna Vecchiarelli
  • Donatella Pietrella
Hours
  • 63 ore - Anna Vecchiarelli
  • 10 ore - Donatella Pietrella
CFU
9
Course Regulation
Coorte 2016
Offered
2017/18
Learning activities
Affine/integrativa
Area
Attività formative affini o integrative
Academic discipline
MED/07
Type of study-unit
Obbligatorio (Required)
Type of learning activities
Attività formativa monodisciplinare
Language of instruction
Italian
Contents
The course aims to provide students with elements to understand the structure and general characteristics of microorganisms. In particular, the bacteria, viruses and protozoa that cause diseases in humans, their pathogenic mechanisms and the spreading of diseases .
Reference texts
Principi di Microbiologia Medica
G. Antonelli, M. Clementi, G. Pozzi, G.M. Rossolini
Educational objectives
The course aims to provide elements to understand the general characteristics of microorganisms, immune responses and their pathogenic mechanisms
Teaching methods
face to face
Learning verification modality
oral examination
Extended program
General Microbiology
Introduction to microorganisms.
Differences between prokariotic cells and eukariotic cells. Bacteria Morphology: cell wall of Gram+ and Gram- bacteria, Peptidoglycan biosynthesis, cytoplasm, nucleus, cytoplasmic membrane, mesosomes, capsule, pili, flagella, spora.
Physiology and metabolism: nutrition, anaerobic and aerobic bacteria, fermentation.
Bacterial growth: different ways to count bacteria, Bacterial growth curve, culture media.
Microbial Genetics: Genetic exchange among bacteria: transformation, transduction, conjugation.
Fungi: definitions, structures, reproduction, virulence factors and pathogenicity.
Virus: classification, structures, viral replication. Virus-Cell Interactions.
Bacterial virulence factors: adhesins, capsule, exoenzymes, toxins). Transmission of infectious diseases. Immunology: the role and functions of the immune system, the non-specific response and the specific response. Primary and secondary lymphoid organs. Cells of the immune system (T lymphocytes, B lymphocytes,macrophages, polymorphonuclear cells). Antigens, immunoglobulins (structure, classes). The major histocompatibility complex, cytokines, Complement system, hypersensitivity reactions (types I, II, III, IV), immune response to infections. Principal microorganisms responsible of human diseases
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