Unit MOLECULAR DIAGNOSTICS IN NEUROPATHOLOGY

Course
Medical, veterinary and forensic biotechnological sciences
Study-unit Code
A001765
Curriculum
In all curricula
CFU
12
Course Regulation
Coorte 2022
Offered
2022/23
Type of study-unit
Obbligatorio (Required)
Type of learning activities
Attività formativa integrata

NEUROLOGY

Code A001766
CFU 6
Teacher Cinzia Costa
Teachers
  • Cinzia Costa
Hours
  • 52 ore - Cinzia Costa
Learning activities Caratterizzante
Area Discipline medico-chirurgiche e riproduzione umana
Academic discipline MED/26
Type of study-unit Obbligatorio (Required)
Language of instruction English
Contents 1) Neuronal physiopathology
2) Resting potential and action potential
3) Synaptic transmission
4) Epileptogenesis
5) Experimental models of epilepsy
6) Neuroprotective effects of antiepileptic drugs during in vitro ischemia
7) Physiopathology of Stroke
8) Synaptic plasticity
9) Experimental models of cerebral ischemia
10) Neurobiology and pathogenesis of Parkinson’s disease and Alzheimer’s disease
11) Laboratory techniques
12) Electrophysiological techniques (extra-cellular, intra-cellular and patch clamp recordings
13) Physiopathological aspects of multiple sclerosis
14) Phatogenetic bases of immuno-modulatory treatment in multiple sclerosis: interferon, beta copolymer 1
Reference texts Principles of Neural Science, Fifth Edition (Principles of Neural Science (Kandel) 5th Edition
by Eric R. Kandel
Educational objectives The main purpose of this course is to provide the fundamental knowledge on the physiopathological bases of neurological diseases. Moreover, the program will focus on the molecular and synaptic mechanisms underlying some neurological diseases, such as Parkinson’s, Huntington’s, and Alzheimer’s, multiple sclerosis, stroke, and epilepsy. The course provides also a practical approach on the use of electrophysiological techniques (extra-, intra-, and patch-clamp-cellular recordings) in experimental brain slice preparations.
Prerequisites Neuron biology basics.
Teaching methods Frontal lessons and practical exercises.
Other information Frequency not mandatory but strongly recommended.
Learning verification modality Written test and final oral exam.
Extended program 1) Neuronal physiopathology
2) Resting potential and action potential
3) Synaptic transmission
4) Epileptogenesis
5) Experimental models of epilepsy
6) Neuroprotective effects of antiepileptic drugs during in vitro ischemia
7) Physiopathology of Stroke
8) Synaptic plasticity
9) Experimental models of cerebral ischemia
10) Neurobiology and pathogenesis of Parkinson’s disease and Alzheimer’s disease
11) Laboratory techniques
12) Electrophysiological techniques (extra-cellular, intra-cellular and patch clamp recordings
13) Physiopathological aspects of multiple sclerosis
14) Phatogenetic bases of immuno-modulatory treatment in multiple sclerosis: interferon, beta copolymer 1
15) Physiopathological aspects of migraine and experimental models

PHYSIOLOGY

Code A001767
CFU 6
Teacher Alessandro Tozzi
Teachers
  • Alessandro Tozzi
  • Miriam Sciaccaluga
Hours
  • 7 ore - Alessandro Tozzi
  • 45 ore - Miriam Sciaccaluga
Learning activities Caratterizzante
Area Discipline biotecnologiche comuni
Academic discipline BIO/09
Type of study-unit Obbligatorio (Required)
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