Unit MOLECULAR DIAGNOSTICS IN NEUROPATHOLOGY
- Course
- Medical, veterinary and forensic biotechnological sciences
- Study-unit Code
- A001765
- Curriculum
- In all curricula
- CFU
- 12
- Course Regulation
- Coorte 2022
- Offered
- 2022/23
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa integrata
NEUROLOGY
Code | A001766 |
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CFU | 6 |
Teacher | Cinzia Costa |
Teachers |
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Hours |
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Learning activities | Caratterizzante |
Area | Discipline medico-chirurgiche e riproduzione umana |
Academic discipline | MED/26 |
Type of study-unit | Obbligatorio (Required) |
Language of instruction | English |
Contents | 1) Neuronal physiopathology 2) Resting potential and action potential 3) Synaptic transmission 4) Epileptogenesis 5) Experimental models of epilepsy 6) Neuroprotective effects of antiepileptic drugs during in vitro ischemia 7) Physiopathology of Stroke 8) Synaptic plasticity 9) Experimental models of cerebral ischemia 10) Neurobiology and pathogenesis of Parkinson’s disease and Alzheimer’s disease 11) Laboratory techniques 12) Electrophysiological techniques (extra-cellular, intra-cellular and patch clamp recordings 13) Physiopathological aspects of multiple sclerosis 14) Phatogenetic bases of immuno-modulatory treatment in multiple sclerosis: interferon, beta copolymer 1 |
Reference texts | Principles of Neural Science, Fifth Edition (Principles of Neural Science (Kandel) 5th Edition by Eric R. Kandel |
Educational objectives | The main purpose of this course is to provide the fundamental knowledge on the physiopathological bases of neurological diseases. Moreover, the program will focus on the molecular and synaptic mechanisms underlying some neurological diseases, such as Parkinson’s, Huntington’s, and Alzheimer’s, multiple sclerosis, stroke, and epilepsy. The course provides also a practical approach on the use of electrophysiological techniques (extra-, intra-, and patch-clamp-cellular recordings) in experimental brain slice preparations. |
Prerequisites | Neuron biology basics. |
Teaching methods | Frontal lessons and practical exercises. |
Other information | Frequency not mandatory but strongly recommended. |
Learning verification modality | Written test and final oral exam. |
Extended program | 1) Neuronal physiopathology 2) Resting potential and action potential 3) Synaptic transmission 4) Epileptogenesis 5) Experimental models of epilepsy 6) Neuroprotective effects of antiepileptic drugs during in vitro ischemia 7) Physiopathology of Stroke 8) Synaptic plasticity 9) Experimental models of cerebral ischemia 10) Neurobiology and pathogenesis of Parkinson’s disease and Alzheimer’s disease 11) Laboratory techniques 12) Electrophysiological techniques (extra-cellular, intra-cellular and patch clamp recordings 13) Physiopathological aspects of multiple sclerosis 14) Phatogenetic bases of immuno-modulatory treatment in multiple sclerosis: interferon, beta copolymer 1 15) Physiopathological aspects of migraine and experimental models |
PHYSIOLOGY
Code | A001767 |
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CFU | 6 |
Teacher | Alessandro Tozzi |
Teachers |
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Hours |
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Learning activities | Caratterizzante |
Area | Discipline biotecnologiche comuni |
Academic discipline | BIO/09 |
Type of study-unit | Obbligatorio (Required) |