Unit CLINICAL SCIENCES

HAEMATOLOGY

Code	50018202
CFU	2
Teacher	Giacomo Muzi
Teachers	Paolo Sportoletti (Codocenza)
Hours	24 ore (Codocenza) - Paolo Sportoletti
Learning activities	Caratterizzante
Area	Scienze interdisciplinari cliniche
Academic discipline	MED/15
Type of study-unit	Obbligatorio (Required)
Language of instruction	Italian
Contents	The module in question is intended to bring to the attention of the student the most important hematologic disorders, new diagnostic tests and their correlation with specific diseases. Provides the necessary elements in order to interpret the meaning of changes in the main laboratory tests
Reference texts	MALATTIE DEL SANGUE E DEGLI ORGANI EMOLINFOPOIETICI- Sante Tura - Editrice ESCULAPIO
Educational objectives	It aims to raise awareness and understanding of the student the meaning of laboratory tests for the purpose of major diseases. In particular, it aims to make early detection of diseases that may emerge from the evaluation of the laboratory tests at the end of the course the student should be able to use the acquired knowledge to identify the most common hematologic diseases
Prerequisites	N/A
Teaching methods	Lectures with presentation of reports and case studies that will give students the chance to meet with real cases in order to learn to be inferred from laboratory data sottese diseases and problems related to them.
Other information	N/A
Learning verification modality	The learning and the degree of preparation is checked by written examination concerning the arguments discussed during the lessons. The students must demonstrate that they have acquired adequate knowledge and skills to recognize the main hematological diseases and related alterations of laboratory tests.
Extended program	1) Hematopoiesis: concepts of general biology and laboratory techniques related to the identification and study of hematopoietic stem cells normal and pathological conditions. 2) leukemogenesis: general overview and pathogenetic mechanisms: laboratory tests related to diagnosis, prognosis, response to treatment and monitoring over time. 3) acute myeloid leukemia and acute leukemias LYMPHOID: generali. Esami concepts inherent laboratory diagnosis, prognosis, response to treatment and monitoring over time. 4) lymphoproliferative syndromes CHRONIC: general overview and differential diagnosis between the various lymphoproliferative diseases 5) chronic myeloproliferative disorders: general overview and differential diagnosis between the various myeloproliferative diseases

OCCUPATIONAL MEDICINE

Code	50788102
CFU	2
Teacher	Giacomo Muzi
Teachers	Giacomo Muzi
Hours	24 ore - Giacomo Muzi
Learning activities	Caratterizzante
Area	Scienze della prevenzione e dei servizi sanitari
Academic discipline	MED/44
Type of study-unit	Obbligatorio (Required)

LEGAL MEDICINE

Code	50667601
CFU	1
Teacher	Laura Paglicci Reattelli
Teachers	Laura Paglicci Reattelli
Hours	12 ore - Laura Paglicci Reattelli
Learning activities	Caratterizzante
Area	Scienze della prevenzione e dei servizi sanitari
Academic discipline	MED/43
Type of study-unit	Obbligatorio (Required)
Language of instruction	Italian
Contents	Biomedical lab technician activities in the judicial inspection and in the forensic tossicology and medico-legal laboratories.
Reference texts	Paolo Arbarello et al. “Medicina Legale per le Professioni Sanitarie: Diritto, Deontologia, Legislazione Sociale” Ed. Minerva Medica, 2010Material provided by the professorSlides
Educational objectives	Know the judicial inspection operating methods and the forensic tossicology and medico-legal analyses.
Prerequisites	Non ci sono pre-requisiti specifici per questa disciplina
Teaching methods	Lessons
Learning verification modality	Oral or written examination
Extended program	Judicial inspectionExamination of the placeExamination of the corpseSurvey of biological tracesThe identification of tracesTraces of bloodTraces of semenForensic toxicologyRegulatory frameworkNeurodepressing drugsOpiatesBarbituratesEthyl alcoholPsychostimulantCocaineHallucinogenic drugsPreparations of cannabis sativaAmphetaminesLSDEthyl alcohol intoxicationPoisoning by carbon monoxide

MEDICAL ONCOLOGY

Code	50667701
CFU	1
Teacher	Giulio Metro
Teachers	Giulio Metro
Hours	12 ore - Giulio Metro
Learning activities	Caratterizzante
Area	Scienze interdisciplinari cliniche
Academic discipline	MED/06
Type of study-unit	Obbligatorio (Required)
Contents	Medical oncology: generalities and principles of target therapy – Breast cancer – Non-small cell lung cancer – Gastrointestinal stromal tumor – Melanoma/Immunotherapy – Molecular biology: characterization of EGFR, KRAS and BRAF genes, liquid biopsy
Educational objectives	The main objective of the course is to provide students with basic notions on the clinically relevant genetic alterations of solid neoplasms which, if identified through specific laboratory tests, may result into the use of targeted therapy.