Unit FUNCTIONAL SEMIOLOGY IN VETERINARY INTERNAL MEDICINE

Course
Veterinary medicine
Study-unit Code
85100006
Curriculum
In all curricula
Teacher
Luca Avellini
CFU
6
Course Regulation
Coorte 2020
Offered
2022/23
Type of study-unit
Obbligatorio (Required)
Type of learning activities
Attività formativa integrata

CLINICAL BIOCHEMISTRY

Code 85002203
CFU 3
Teacher Luca Avellini
Teachers
  • Luca Avellini
Hours
  • 30 ore - Luca Avellini
Learning activities Affine/integrativa
Area Attività formative affini o integrative
Academic discipline BIO/12
Type of study-unit Obbligatorio (Required)
Language of instruction Italian
Contents Knowledge necessary to understand the process of production of laboratory data for its critical interpretation. Basic concepts of analytical variability and biological variation, pre-analytical phase, reference values and quality control. Basic concepts of the most used techniques. Point-of-Care testing; Biochemical markers of function or damage of tissues or organs in different animal species.
Reference texts S. Paltrinieri, W. Bertazzolo, A. Giordano - Patologia clinica del cane e del gatto. Masson
Meyer D.J. Harvey J.W. - Medicina di laboratorio veterinaria– interpretazione e diagnosi. Delfino Editore
Ciaccio, Lippi - Biochimica Clinica e Medicina di Laboratorio - EdiSES
Educational objectives KNOWLEDGE AND UNDERSTANDING
The student must have knowledge of:
- the interpretation ability of clinical laboratory data
- the meaning and limits of clinical laboratory data;
- correct application of bio-security principles in clinical biochemistry lab.
- collection, preservation and transport of biological samples;
APPLYING KNOWLEDGE AND UNDERSTANDING
At the end of the course the student must have developed the following skills:
- to use the simplest analytical instruments;
- select appropriate diagnostic tests based on its analytical quality.
AUTONOMY OF JUDGMENT
The student must be able to:
- Communicate clearly and collaborate with referral and diagnostic services;
- interpret and understand the limitations of the test results.
COMMUNICATION SKILLS
At the end of the course, the student must be able to organize and expose the acquired knowledge supporting them with argumentative rigor, completeness, language properties and connection skills into other contexts both in written and oral form.
LIFELONG LEARNING SKILLS
At the end of the course the student will be able to:
- integrate autonomously the acquired knowledge by consulting and understanding scientific texts or bibliographic updates, so as to employ them in different contexts, including research;
- use the acquired know-how to understand the contents of teachings such as laboratory diagnostics, medical clinics, medical therapy.
Prerequisites
Teaching methods The course is organized as follow:

- Lectures (26 hours) on all subjects of the course

- n° 2 laboratory exercises (overall 4 hours) will be done at the teaching lab (basement of the main building) for the knowledge/solution of basic problems regarding clinical chemistry lab. Students will be divided into groups (maximum 20 students per group).
Learning verification modality
Extended program ANALYTICAL TECHNIQUES and ANALYTICAL QUALITY:
Basic concepts of reliability analytical: precision, trueness, accuracy, sensitivity and specificity, the quality management. The internal quality control. Predictive value and decision-making levels.
Quantities and units of measurement in clinical biochemistry, pre-analytical variability, reference values and biological variability, the concept of critical difference and goal of analytical quality; diagnostic sensitivity and specificity.
Principles and techniques for collecting, processing and storage of biological samples.
Basic concepts of the techniques most commonly used in clinical biochemistry, with particular reference to the basic principles and applications of enzymatic techniques. Point-of-Care testing. Dry Chemistry: principles and its use in the examination of urine and in ambulatory monitoring of blood glucose. Blood gas analyzer.

Biochemical markers of function or damage of tissues or organs in different animal species with particular reference to: disorders of fluid and electrolyte metabolism and acid-base (blood gas analysis); markers of liver function: electropherogram of blood serum, heme metabolism and jaundice, coagulation tests; diabetes mellitus and dynamic tests of endocrine function of the pancreas. Clinical biochemistry of transmissible spongiform encephalopathies. Clinical enzymology. Clinical biochemistry of exercise.
Practical lessons:
Principles of good laboratory practice, evaluation of a method precision.
Urine examination by dry chemistry. Glucose analysis methods.

LABORATORY DIAGNOSTIC IN CLINICAL PRACTICE

Code 85107303
CFU 3
Teacher Arianna Miglio
Teachers
  • Arianna Miglio
  • Maria Teresa Antognoni (Codocenza)
Hours
  • 5 ore - Arianna Miglio
  • 34 ore (Codocenza) - Maria Teresa Antognoni
Learning activities Caratterizzante
Area Discipline cliniche veterinarie
Academic discipline VET/08
Type of study-unit Obbligatorio (Required)
Language of instruction Italian
Contents
Reference texts notes from teacher

Testi di consultazione: S. Paltrinieri, W. Bertazzolo, A. Giordano - Patologia clinica del cane e del gatto. Masson

Meyer D.J. Harvey J.W. - Medicina di laboratorio veterinaria– interpretazione e diagnosi. Delfino Editore

Michael D., Willard - Smal animal Clinical diagnosis by laboratory methods. Fifth edition. Elsevier
Educational objectives The main goal of education is to provide students with the foundation to address the study and knowledge of the main laboratory parameters are designed to veil diseases of organ and to learn to grasp the clinical significance in relation to various diseases.

The main skills are:

knowledge about the sampling procedure and storage of various materials

knowledge related to laboratory parameters such as markers of organ function, in different animal species

The main skills are:

perform surveys in specialized laboratories

analyze the data coming from the different samples

interpret data to identify diseases of organ and to address a differential diagnosis
Teaching methods Theoretical lessons and practical training
Learning verification modality oral examination
Extended program General laboratory concepts:sources of laboratory error; preanalytical errors: hemolysis, lipemia, icterus. Analitical errors. Sample collection. Metabolic profile.
Serum total protein. Protein electrophoresis; Altered electrophoretic patterns; Acute fase proteinsHyperglobulinemia, hypoglobulinemia, monoclonal gammopathy.
Hepatic disorders. Nefrology disorders. Urynary disorders.
Hemostatic abnormalities.
Fluid accumulation disorders: diagnostic approach, fluid collection technique, characterization of fluid. Gastrointestinal and pancreatic disorders. Cardiac disorders. Endocrine disorders
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