Unit RESEARCH METHODOLOGY

ELECTRONIC BIOENGEENERING AND INFORMATICS

Code	50998703
CFU	3
Teacher	Elisabetta Zanetti
Teachers	Elisabetta Zanetti
Hours	24 ore - Elisabetta Zanetti
Learning activities	Caratterizzante
Area	Scienze informatiche applicate alla gestione sanitaria
Academic discipline	ING-INF/06
Type of study-unit	Obbligatorio (Required)
Language of instruction	Italian
Contents	Bioengineering and Informatics principles
Reference texts	Slided projected during lectures and uploaded on Unistudium platform
Educational objectives	Basical knowledge of medical instrumentation and of techniques to elaborate signals and images. Biomechanics and mechanical technology.
Prerequisites	Basic mathematics and physics
Teaching methods	Frontal lectures and informatic sessions
Other information	Further information can be requested via email
Learning verification modality	Written test: 12 questions with short answers (1h 30’)
Extended program	Introduction to bioengineering Specifications and calibration of a measuring system Frequency analysis of signals Signals digitalization Bioimages 3D modelling and fast prototyping Properties of materials PC, its main hardware, web connections. Health Informatics: ICD, DRG, SNOMED, Electronic health folder, RIS/PACS Directives concerning electrical safety

RESEARCH METHODOLOGY IN REHABILITATION

Code	50995101
CFU	3
Teacher	Daniela Gaburri
Teachers	Daniela Gaburri
Hours	30 ore - Daniela Gaburri
Learning activities	Caratterizzante
Area	* scienze della fisioterapia
Academic discipline	MED/48
Type of study-unit	Obbligatorio (Required)
Language of instruction	italian
Contents	Purposes and methods of EBM / EBP. EBP in five steps. EBP question fomation P.I.C.O Search for evidence in the literature. Critical appraisal
Reference texts	Educational material provided by the teacher
Educational objectives	Knowledge of purposes and methods of practice based on evidence Ability to apply knowledge and understanding in relation to the formulation of clinical questions Ability to conduct literature searches Ability of critical reading of scientific works
Prerequisites	Surf the web Basic knowledge of english
Teaching methods	Traditional lectures Practice
Other information	no one
Learning verification modality	Develop a paper
Extended program	General Aspects - Definition of evidence-based practice (EBP) understood as the integration of the best scientific evidence with clinical expertice and individual patient values and circumstances - The rationale for EBP - Advantages and limitations of the main study designs, identifying their correct hierarchy - The 5 steps of EBP: formulating clinical questions, researching, appraising and applying evidence, monitoring performance - Difference between using evidence to inform clinical decisions and producing evidence Formulating clinical questions - Foreground and background clinical questions - Different types of clinical questions: etiology, diagnosis, prognosis, treatment - Structuring clinical questions using the PICO model Searching for evidence - Primary sources where to search for scientific evidence: primary databases, evidence databases, and "filtered" or "pre-appraised" resources - Search strategy for clinical questions - Different areas covered by the main databases - Obtain full text of articles Critically evaluate and interpret evidence - Critically evaluate internal validity, clinical relevance, and applicability and integrity of clinical research - Critical appraisal and interpretation of various study types (RCTs, Systematic Reviews)

STATISTICS FOR EXPERIMENTAL RESEARCH

Code	50997402
CFU	2
Teacher	Lucio Patoia
Teachers	Lucio Patoia
Hours	16 ore - Lucio Patoia
Learning activities	Caratterizzante
Area	Statistica ed epidemiologia
Academic discipline	MED/01
Type of study-unit	Obbligatorio (Required)
Language of instruction	Italian
Contents	Biomedical reearch principles:basic research, clinical research Systematic reviews The measurements in biology Descriptive statistics
Reference texts	Pamphlet and slides provided from the professor
Educational objectives	1) To give information useful for critically read the different clinical studies, and expecially RCT and systematic reviews. 2) To give informations on both descriptive and inferential statistics useful to the didactic objective n.1
Prerequisites	none
Teaching methods	Lectures and practical exercises
Other information
Learning verification modality	Multiple choice tests.
Extended program	Biomedical reearch principles. Basic research, clinical research. Diferent types of clinical research: randomised controlled clinical trials, systematic reviews, case-control studies, cohort studies, survey studies, qualitative studies. The experimental method principles: RCT structure, the control group, the random, the blind (double and single), the parallel groups, the symmetry in clinical research conduction, the completeness of follow up. Systematic reviews: methodological quality of primary studies, qualitative or quantitative summary of informations, the methanalysis, the relative risk, the odds ratio, the confidence interval, the forest plot, the weight of different studies enclosed, the heterogeneity, discussione of reasons of concordance or discordance between studies results. The measurements in biology: variability of biological phenomenon, the constants and the variables. Quantitative and qualitative, continuos or discrete variables. The measures: .the scales of measurements, the errors in measurements, accuracy, precision. Diagnostic tests: sensibility, specificity, positive/negtive predictive values. Descriptive statistics: objectives, mean, median, mode. Normal curve of distribution. Range, deviation from mean, , variance, standard deviation. Inferential statistics, the statistical model, the null hypothesis and the alternative hypothesis, type I and type II error, the punctual exstimate and the confidence interval.

TECHNOLOGIES AND RECOMBINANTS APPLIED TO REHABILITATION

Code	50995001
CFU	1
Teacher	Vincenzo Nicola Talesa
Teachers	Vincenzo Nicola Talesa
Hours	8 ore - Vincenzo Nicola Talesa
Learning activities	Caratterizzante
Area	Scienze biomediche e psicologiche
Academic discipline	BIO/13
Type of study-unit	Obbligatorio (Required)
Language of instruction	Italian
Contents	Use of stem cells for cell regeneration
Reference texts	Notes of the teacher
Educational objectives	Knowledge of methodologies and technologies applied to rehabilitation
Prerequisites	Knowledge of biology, physics and chemistry
Teaching methods	Frontal lesson
Learning verification modality	Written multiple choice exams and oral exam For information on support services for students with disabilities and / or DSA visit the page http://www.unipg.it/disabilita-e-dsa
Extended program	Stamina cells Regeneration of bone tissue Cartilage tissue regeneration. Tissue engineering techniques for the creation of bio-materials of osteo-articular interest.