Unit MICROBIOLOGY AND HYGIENE
- Course
- Pharmacy
- Study-unit Code
- A003565
- Location
- PERUGIA
- Curriculum
- In all curricula
- Teacher
- Massimo Moretti
- CFU
- 12
- Course Regulation
- Coorte 2023
- Offered
- 2024/25
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa integrata
HYGIENE AND PUBLIC HEALTH
| Code | 65003512 |
|---|---|
| Location | PERUGIA |
| CFU | 6 |
| Teacher | Massimo Moretti |
| Teachers |
|
| Hours |
|
| Learning activities | Base |
| Area | Discipline mediche |
| Academic discipline | MED/42 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian. |
| Contents | Primary, secondary and tertiary prevention of diseases. Epidemiology and prevention of infectious and chronic diseases. Health education and health promotion. Passive and active immunization: sera and vaccines. Cancer screening tests. |
| Reference texts | Pontello M. & Auxilia F. "Igiene, Medicina Preventiva e salute Globale" - Piccin, Padova. |
| Educational objectives | The learning experiences should help students in achieving attitudes and practices related to critical health issues: role of Pharmacists in diseases prevention and health education and promotion; Pharmacists as health experts of the National Health Service (NHS). |
| Prerequisites | None. |
| Teaching methods | Face-to-face lessons. |
| Other information | Co-Teaching (4 h): Prof. Milena Villarini. |
| Learning verification modality | Written (closed-ended questions). |
| Extended program | Introduction to Hygiene and Public Health; concepts of health and disease. Determinants of health. Natural history of disease. Principles of health economics. Health management: National Health Service (NHS), Local Health Units and Hospitals. General disease prevention: health promotion/protection. Levels of disease prevention: primary, secondary and tertiary prevention. Epidemiology and prevention of infectious diseases. Etiologic agent: definition. Routes of transmission of infectious disease agents: sexually transmitted diseases; bloodborne, airborne, vehicle(water)borne and vectorborne transmission. Ectoparasites: Pulex spp. (flea), Pediculus spp. (louse), Pthirus spp. (crab louse), Sarcoptes spp. (dust mite). Arthropod-transmitted diseases. Endoparasites: protozoans (Giardia spp.), flatworms (Taenia spp.) e nematodes (Dracunculus spp., Ascaris spp.). Vector-transmitted parasites: Plasmodium spp. (malaria), Leishmania spp. Principles of disinfection; classification of disinfectants; disinfectants in pharmacy. Sterilization; classification of methods of sterilization; controls of sterilization. Disinfestation and pest control; methods of mosquito control; management and control of pediculosis; rodent prevention and control. Immunoprophylaxis: sera/immunoglobulins and vaccines. Classification of vaccines: inactivated or engineered vaccines and toxoids; whole-cell and fractional vaccines; live attenuated vaccines; new vaccines. Epidemiology and control of selected vaccine-prevented diseases. Vaccinal strategies: control (tetanus), elimination (diphteria), eradication (smallpox) of infectious diseases. Immunization schedule for children; immunization of adults and travellers. Emerging infectious diseases (Legionella pneumophila; Escherichia coli O157:H7). Opportunistic infections. Hospital-acquired infections. Food hygiene; prevention of food-borne diseases; food safety legislation; control of food-borne diseases in pharmacy; HACCP method. Epidemiology and prevention of principal chronic diseases: cardiovascular diseases (CVD), cancer, diabetes, chronic obstructive pulmonary disease (COPD). CVD: the Framingham cohort. Prevention and control of infarction and ictus. Epidemiology and prevention of cancer. Mutagenesis and carcinogenesis processes. Secondary prevention (early diagnosis) of cancer. Cancer screening test: fecal occult blood (FOB), Pap-test, mammography. Epidemiology and prevention of diabetes and metabolic syndrome. Epidemiology and prevention of respiratory diseases: COPD and asthma. Tobacco smoking and health; prevention of (active/passive) smoking-related diseases. Methods of giving up smoking and nicotine replacement therapy; role of pharmacists in anti-smoking efforts. Health education: methods for health promotion (relationship between health and human behavior). Role of the pharmacist in health education and promotion; evidence of effectiveness of pharmacy-based health promotion. New health services in the pharmacy (D.L. n. 153, 3 October, 2009). Oral health; epidemiology and prevention of caries, parodontopathy and oral cancer; principles of oral hygiene. Environmental health; drinking water and health; methods of treatment of drinking water; mineral water and health; drinking water hardness and health. |
| Obiettivi Agenda 2030 per lo sviluppo sostenibile | Goal 3: Good health and well-being. Goal 6: Clean water and sanitation. |
GENERAL AND CLINICAL MICROBIOLOGY
| Code | A003564 |
|---|---|
| Location | PERUGIA |
| CFU | 6 |
| Teacher | Donatella Pietrella |
| Teachers |
|
| Hours |
|
| Learning activities | Base |
| Area | Discipline mediche |
| Academic discipline | MED/07 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian |
| Contents | Cellular organization, metabolism and genetics of bacteria, fungi and viruses. The microbial virulence factors and infection transmission routes. Infection control strategies (vaccines and antimicrobials). Disinfection and Sterilization Main microorganisms involved in human infections |
| Reference texts | Carlone N, Pompei R. Microbiologia farmaceutica. Edises G. Antonelli, M. Clementi, G. Pozzi, G.M. Rossolini. Principi di Microbiologia Medica. Casa Editrice Ambrosiana Terza Edizione (2017) |
| Educational objectives | The purpose of the present course is to acquire the following knowledge: Cellular organization, metabolism, genetics of microorganisms Positive and negative interactions between organism and man. Pathogenetic mechanisms of microbial infections; Vaccines in the containment of infection. Molecular targets for antimicrobial drugs Antibiotic resistance: mechanisms and prevention strategies. |
| Prerequisites | For the understanding of the course the student should have basic knowledge of cellular and molecular biology, anatomy, physiology and biochemistry. |
| Teaching methods | 24 Lectures |
| Other information | Recommended attendance |
| Learning verification modality | Oral examination. The test consists of a discussion of the topics covered in class. Knowledge of the subject, of the specific language acquired and presentation ability will be assessed. For information on support services for students with disabilities and/or DSA visit the page http://www.unipg.it/disabilita-e-dsa |
| Extended program | History of microbiology. Prokaryotic and eukaryotic microorganisms, general characteristics. Classification and nomenclature of microorganisms. The human microbiota. Biotechnology in the pharmaceutical field. General bacteriology: Structures of the bacterial cell. Classification and morphology of bacteria, bacterial metabolism. Spores. Bacterial physiology and metabolism: nutrition, respiration, fermentation. Bacterial growth: bacterial count, growth curve, culture media. Bacterial genetics (transduction, conjugation and transformation) and gene regulation mechanisms. Virulence factors: adhesins, capsule, exoenzymes, bacterial toxins (characteristics and mechanism of action), biofilm formation. Antibacterial drugs. Main classes (wall and protein synthesis inhibitors, transcription, DNA replication, bacterial metabolism inhibitors) and related mechanisms of bacterial resistance. Antibiogram. Main bacteria of clinical interest (Clostridia, Staphylococci, Streptococci, Escherichia coli, Pseudomonas aeruginosa, Mycobacterium tuberculosis). General virology: Viruses. Classification, structure and replication of viruses. Viral pathogenesis. Antiviral drugs. General principles for laboratory diagnosis: serological and molecular diagnosis. Main pathogenic viruses in humans: orthomyxovirus, hepatitis virus, measles virus, herpesvirus, rubella virus, mumps virus, HIV papillomavirus, poliovirus, coronavirus General mycology and protozoology: General information. Pathogenicity mechanisms. Superficial mycosis and deep mycosis. Antifungal drugs. Candida albicans. Toxoplasma gondii and Plasmodium |