Unit SYSTEMIC PATHOLOGY V
- Course
- Medicine and surgery
- Study-unit Code
- GP004561
- Curriculum
- In all curricula
- CFU
- 12
- Course Regulation
- Coorte 2020
- Offered
- 2023/24
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa integrata
BLOOD DISEASES - MOD. 1
| Code | GP004621 |
|---|---|
| CFU | 2 |
| Learning activities | Caratterizzante |
| Area | Fisiopatologia, metodologia clinica, propedeutica clinica e sistematica medico-chirurgica |
| Academic discipline | MED/15 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 2
- Teacher
- Maria Paola Martelli
- Teachers
- Maria Paola Martelli
- Hours
- 25 ore - Maria Paola Martelli
- Language of instruction
- Italian
- Contents
- The myeloproliferative syndromes:
- Chronic myeloid leukemia
- Idiopathic myelofibrosis
- Polycythemia Vera
- Essential thrombocythemia
The myelodysplastic syndromes
The acute leukemias
- Acute myeloid and lymphoid leukemias
- Classification and clinical presentation.
- Key molecular alterations associated
- Examples of 'target' therapy
Chronic lymphoproliferative disorders:
- Chronic lymphocytic leukemia
- The hairy cell leukemia
The malignant lymphomas
- Hodgkin's disease
- Non-Hodgkin's Lymphoma
The monoclonal gammopathy
- MGUS
- Multiple Myeloma
- Waldenstrom's Macroglobulinemia - Reference texts
- Harrison's - Principles of Internal Medicine
Hoffbrand/Moss - Essential Haematology
Bosi, De Stefano, Di Raimondo, La Nasa – Manuale di Malattie del Sangue
Avvisati – Ematologia di Mandelli
Hoffman - Hematology basic principles and practice - Educational objectives
- The learning outcomes are compliant with the provisions in the didactic published at: http: //www.med.unipg.it/ccl (http://www.med.unipg.it/ccl)
In detail, the general objective of education is to provide students with the foundation to address the study of blood diseases (either malignant or not). - Prerequisites
- In order to understand and know how to tackle the course, students must have the basic understanding on:
- Physiology of blood, features and functions of the elements of blood (leukocytes, erythrocytes and platelets)
- Anatomy, organization and functions of the lymphatic system
- Cellular and humoral immunity
- Structure of the bone marrow and hematopoiesis
- The blood count
- Principles of Serum protein electrophoresis
- The monoclonal antibodies - Teaching methods
- Face to face lessons. Clinical cases discussion.
- Learning verification modality
- METHOD OF CONDUCTING THE EXAM: oral test (lasting about 15-20 minutes) will be assessed the acquired knowledge and the student's ability to communicate and reason confronted with a specific question. The oral exam consists of a discussion-interview on the topics covered during the course or at least in the program and in-depth texts Recommended. For Blood Diseases Teaching a topic of oncohematology and non malignant disease will be addressed.
TESTING OF CLINICAL SKILLS: interpretation of a blood count, discussion of a clinical case.
METHOD OF ALLOCATION OF THE FINAL MARK: arithmetic average of the marks obtained in the individual disciplines - Extended program
- The myeloproliferative syndromes:
- Chronic myeloid leukemia
- Idiopathic myelofibrosis
- Polycythemia Vera
- Essential thrombocythemia
The myelodysplastic syndromes
The acute leukemias
- Acute myeloid and lymphoid leukemias
- Classification and clinical presentation.
- Key molecular alterations associated
- Examples of 'target' therapy
Chronic lymphoproliferative disorders:
- Chronic lymphocytic leukemia
- The hairy cell leukemia
The malignant lymphomas
- Hodgkin's disease
- Non-Hodgkin's Lymphoma
The monoclonal gammopathy
- MGUS
- Multiple Myeloma
- Waldenstrom's Macroglobulinemia
Cognomi M-Z
- CFU
- 2
- Teacher
- Maria Paola Martelli
- Teachers
- Maria Paola Martelli
- Hours
- 25 ore - Maria Paola Martelli
- Language of instruction
- Italian
- Contents
- The myeloproliferative syndromes:
- Chronic myeloid leukemia
- Idiopathic myelofibrosis
- Polycythemia Vera
- Essential thrombocythemia
The myelodysplastic syndromes
The acute leukemias
- Acute myeloid and lymphoid leukemias
- Classification and clinical presentation.
- Key molecular alterations associated
- Examples of 'target' therapy
Chronic lymphoproliferative disorders:
- Chronic lymphocytic leukemia
- The hairy cell leukemia
The malignant lymphomas
- Hodgkin's disease
- Non-Hodgkin's Lymphoma
The monoclonal gammopathy
- MGUS
- Multiple Myeloma
- Waldenstrom's Macroglobulinemia - Reference texts
- Harrison's - Principles of Internal Medicine
Hoffbrand/Moss - Essential Haematology
Bosi, De Stefano, Di Raimondo, La Nasa – Manuale di Malattie del Sangue
Avvisati – Ematologia di Mandelli
Hoffman - Hematology basic principles and practice - Educational objectives
- The learning outcomes are compliant with the provisions in the didactic published at: http: //www.med.unipg.it/ccl (http://www.med.unipg.it/ccl)
In detail, the general objective of education is to provide students with the foundation to address the study of blood diseases (either malignant or not). - Prerequisites
- In order to understand and know how to tackle the course, students must have the basic understanding on:
- Physiology of blood, features and functions of the elements of blood (leukocytes, erythrocytes and platelets)
- Anatomy, organization and functions of the lymphatic system
- Cellular and humoral immunity
- Structure of the bone marrow and hematopoiesis
- The blood count
- Principles of Serum protein electrophoresis
- The monoclonal antibodies - Teaching methods
- Face to face lessons. Clinical cases discussion.
- Learning verification modality
- METHOD OF CONDUCTING THE EXAM: oral test (lasting about 15-20 minutes) will be assessed the acquired knowledge and the student's ability to communicate and reason confronted with a specific question. The oral exam consists of a discussion-interview on the topics covered during the course or at least in the program and in-depth texts Recommended. For Blood Diseases Teaching a topic of oncohematology and non malignant disease will be addressed.
TESTING OF CLINICAL SKILLS: interpretation of a blood count, discussion of a clinical case.
METHOD OF ALLOCATION OF THE FINAL MARK: arithmetic average of the marks obtained in the individual disciplines - Extended program
- The myeloproliferative syndromes:
- Chronic myeloid leukemia
- Idiopathic myelofibrosis
- Polycythemia Vera
- Essential thrombocythemia
The myelodysplastic syndromes
The acute leukemias
- Acute myeloid and lymphoid leukemias
- Classification and clinical presentation.
- Key molecular alterations associated
- Examples of 'target' therapy
Chronic lymphoproliferative disorders:
- Chronic lymphocytic leukemia
- The hairy cell leukemia
The malignant lymphomas
- Hodgkin's disease
- Non-Hodgkin's Lymphoma
The monoclonal gammopathy
- MGUS
- Multiple Myeloma
- Waldenstrom's Macroglobulinemia
BLOOD DISEASES - MOD. 2
| Code | GP004622 |
|---|---|
| CFU | 1 |
| Learning activities | Caratterizzante |
| Area | Fisiopatologia, metodologia clinica, propedeutica clinica e sistematica medico-chirurgica |
| Academic discipline | MED/15 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 1
- Teacher
- Maria Paola Martelli
- Teachers
- Antonio Pierini (Codocenza)
- Hours
- 12.5 ore (Codocenza) - Antonio Pierini
- Language of instruction
- Italian
- Contents
- The anemias:
- General aspects of anemia and erythropoiesis
- Classification of anemia: a. etiopathogenetic; b. morphological
- Morphological alterations of red blood cells. The smear of peripheral venous blood
- Iron deficiency anemia
- Megaloblastic Anemia and other macrocytic anemias
- Anemia of chronic disorders
- Hemolytic anemias
Hemolytic hereditary disorders
Extraglobular causes of hemolytic disorders
- Thalassemias
- Aplastic anemia and other selective cytopenias (erythroblastopenia isolated, neutropenia and
thrombocytopenia)
- Differential diagnosis of anemic syndromes. Discussion of clinical cases and diagnostic work.
The thrombocytopenia.
- Idiopathic Thrombocytopenia Purpura
- Thrombotic thrombocytopenia purpura
Issues of general haematological interest:
- Numerical changes of blood elements:
a. differential diagnosis of erythrocytosis
b. leukopenia and leukocytosis (lymphopenia and lymphocytosis, neutropenia and neutrophilia)
c. thrombocytopenia and thrombocytosis
- Splenomegaly.
- Splenectomy. Indications in hematology and complications
- Lymphadenopathy: Differential Diagnosis
- Hematological alterations in systemic diseases - Reference texts
- Harrison's - Principles of Internal Medicine
Hoffbrand/Moss - Essential Haematology
Bosi, De Stefano, Di Raimondo, La Nasa – Manuale di Malattie del Sangue
Avvisati – Ematologia di Mandelli
Hoffman - Hematology basic principles and practice - Educational objectives
- The learning outcomes are compliant with the provisions in the didactic published at: http: //www.med.unipg.it/ccl (http://www.med.unipg.it/ccl)
In detail, the general objective of education is to provide students with the foundation to address the study of blood diseases (either malignant or not). - Prerequisites
- In order to understand and know how to tackle the course, students must have the basic understanding on:
- Physiology of blood, features and functions of the elements of blood (leukocytes, erythrocytes and platelets)
- Anatomy, organization and functions of the lymphatic system
- Cellular and humoral immunity
- Structure of the bone marrow and hematopoiesis
- The blood count
- Principles of Serum protein electrophoresis
- The monoclonal antibodies - Teaching methods
- Face to face lessons. Clinical cases discussion.
- Learning verification modality
- METHOD OF CONDUCTING THE EXAM: oral test (lasting about 15-20 minutes) will be assessed the acquired knowledge and the student's ability to communicate and reason confronted with a specific question. The oral exam consists of a discussion-interview on the topics covered during the course or at least in the program and in-depth texts Recommended. For Blood Diseases Teaching a topic of oncohematology and non malignant disease will be addressed.
TESTING OF CLINICAL SKILLS: interpretation of a blood count, discussion of a clinical case.
METHOD OF ALLOCATION OF THE FINAL MARK: arithmetic average of the marks obtained in the individual disciplines - Extended program
- The anemias:
- General aspects of anemia and erythropoiesis
- Classification of anemia: a. etiopathogenetic; b. morphological
- Morphological alterations of red blood cells. The smear of peripheral venous blood
- Iron deficiency anemia
- Megaloblastic Anemia and other macrocytic anemias
- Anemia of chronic disorders
- Hemolytic anemias
Hemolytic hereditary disorders
Extraglobular causes of hemolytic disorders
- Thalassemias
- Aplastic anemia and other selective cytopenias (erythroblastopenia isolated, neutropenia and
thrombocytopenia)
- Differential diagnosis of anemic syndromes. Discussion of clinical cases and diagnostic work.
The thrombocytopenia.
- Idiopathic Thrombocytopenia Purpura
- Thrombotic thrombocytopenia purpura
Issues of general haematological interest:
- Numerical changes of blood elements:
a. differential diagnosis of erythrocytosis
b. leukopenia and leukocytosis (lymphopenia and lymphocytosis, neutropenia and neutrophilia)
c. thrombocytopenia and thrombocytosis
- Splenomegaly.
- Splenectomy. Indications in hematology and complications
- Lymphadenopathy: Differential Diagnosis
- Hematological alterations in systemic diseases
Cognomi M-Z
- CFU
- 1
- Teacher
- Maria Paola Martelli
- Teachers
- Antonio Pierini (Codocenza)
- Hours
- 12.5 ore (Codocenza) - Antonio Pierini
- Language of instruction
- Italian
- Contents
- The anemias:
- General aspects of anemia and erythropoiesis
- Classification of anemia: a. etiopathogenetic; b. morphological
- Morphological alterations of red blood cells. The smear of peripheral venous blood
- Iron deficiency anemia
- Megaloblastic Anemia and other macrocytic anemias
- Anemia of chronic disorders
- Hemolytic anemias
Hemolytic hereditary disorders
Extraglobular causes of hemolytic disorders
- Thalassemias
- Aplastic anemia and other selective cytopenias (erythroblastopenia isolated, neutropenia and
thrombocytopenia)
- Differential diagnosis of anemic syndromes. Discussion of clinical cases and diagnostic work.
The thrombocytopenia.
- Idiopathic Thrombocytopenia Purpura
- Thrombotic thrombocytopenia purpura
Issues of general haematological interest:
- Numerical changes of blood elements:
a. differential diagnosis of erythrocytosis
b. leukopenia and leukocytosis (lymphopenia and lymphocytosis, neutropenia and neutrophilia)
c. thrombocytopenia and thrombocytosis
- Splenomegaly.
- Splenectomy. Indications in hematology and complications
- Lymphadenopathy: Differential Diagnosis
- Hematological alterations in systemic diseases - Reference texts
- Harrison's - Principles of Internal Medicine
Hoffbrand/Moss - Essential Haematology
Bosi, De Stefano, Di Raimondo, La Nasa – Manuale di Malattie del Sangue
Avvisati – Ematologia di Mandelli
Hoffman - Hematology basic principles and practice - Educational objectives
- The learning outcomes are compliant with the provisions in the didactic published at: http: //www.med.unipg.it/ccl (http://www.med.unipg.it/ccl)
In detail, the general objective of education is to provide students with the foundation to address the study of blood diseases (either malignant or not). - Prerequisites
- In order to understand and know how to tackle the course, students must have the basic understanding on:
- Physiology of blood, features and functions of the elements of blood (leukocytes, erythrocytes and platelets)
- Anatomy, organization and functions of the lymphatic system
- Cellular and humoral immunity
- Structure of the bone marrow and hematopoiesis
- The blood count
- Principles of Serum protein electrophoresis
- The monoclonal antibodies - Teaching methods
- Face to face lessons. Clinical cases discussion.
- Learning verification modality
- METHOD OF CONDUCTING THE EXAM: oral test (lasting about 15-20 minutes) will be assessed the acquired knowledge and the student's ability to communicate and reason confronted with a specific question. The oral exam consists of a discussion-interview on the topics covered during the course or at least in the program and in-depth texts Recommended. For Blood Diseases Teaching a topic of oncohematology and non malignant disease will be addressed.
TESTING OF CLINICAL SKILLS: interpretation of a blood count, discussion of a clinical case.
METHOD OF ALLOCATION OF THE FINAL MARK: arithmetic average of the marks obtained in the individual disciplines - Extended program
- The anemias:
- General aspects of anemia and erythropoiesis
- Classification of anemia: a. etiopathogenetic; b. morphological
- Morphological alterations of red blood cells. The smear of peripheral venous blood
- Iron deficiency anemia
- Megaloblastic Anemia and other macrocytic anemias
- Anemia of chronic disorders
- Hemolytic anemias
Hemolytic hereditary disorders
Extraglobular causes of hemolytic disorders
- Thalassemias
- Aplastic anemia and other selective cytopenias (erythroblastopenia isolated, neutropenia and
thrombocytopenia)
- Differential diagnosis of anemic syndromes. Discussion of clinical cases and diagnostic work.
The thrombocytopenia.
- Idiopathic Thrombocytopenia Purpura
- Thrombotic thrombocytopenia purpura
Issues of general haematological interest:
- Numerical changes of blood elements:
a. differential diagnosis of erythrocytosis
b. leukopenia and leukocytosis (lymphopenia and lymphocytosis, neutropenia and neutrophilia)
c. thrombocytopenia and thrombocytosis
- Splenomegaly.
- Splenectomy. Indications in hematology and complications
- Lymphadenopathy: Differential Diagnosis
- Hematological alterations in systemic diseases
DISEASES OF THE IMMUNE SYSTEM
| Code | GP005656 |
|---|---|
| CFU | 2 |
| Learning activities | Caratterizzante |
| Area | Medicina delle attività motorie e del benessere |
| Academic discipline | MED/09 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 2
- Teacher
- Antonio Pierini
- Teachers
- Antonio Pierini
- Hours
- 25 ore - Antonio Pierini
- Language of instruction
- Italian
- Contents
- Physiology of the human immune system.
The immunodeficiencies:
Pathogenetic mechanisms of infectious risk and diagnostics of immunodeficiencies.
Primary immunodeficiencies:
Severe Combined Immunodeficiencies.
Antibody deficiency diseases.
Complement deficiency diseases
Immunodeficiencies due to granulocyte function deficit
New pathogenetic mechanisms of immune deficiencies and cytopenias
Secondary immunodeficiencies:
AIDS: immuno-pathogenesis, natural history of the disease, main clinical pictures.
Immunodeficiencies due to immunosuppressive and cytostatic drugs
Splenectomy
Immunodeficiencies due to neoplastic diseases
Hematopoietic cell transplantation: basic principles, donor choice,
infectious complications, tolerance and engraftment, graft versus host disease
Antibody and cellular immunotherapy
Principles of immunotherapy of neoplastic and autoimmune diseases
Checkpoint inhibitors
Cellular immunotherapy
Hypersensitivity diseases
Pathophysiology of allergic diseases: hypersensitivity types I, II, III, IV
Immediate hypersensitivity clinical syndromes: Urticaria and angiodema, Food allergies,
Allergic rhinitis, asthma, anaphylactic shock.
Immunological pathogenesis and clinical pictures of the main organ autoimmune diseases
specifications
Hashimoto's thyroiditis
Multiple sclerosis,
autoimmune cytopenias,
aplastic anemia,
Celiac disease
Immune complex diseases and vasculitis:
Purple of the Schonlein-Henoch,
serum sickness,
Cryoglobulinemias
Clinical Immunology of Vaccines - Reference texts
- HARRISON " Principles of Internal Medicine"
- Educational objectives
- At the end of the course the student will have to be able to know and to frame, from a clinical and diagnostic point of view , the main diseases of the immunity system., pimary and secondary systemic autoimmunities and immunodeficiency. The verification of the real acquisizioneis of the student will be carried out during examination.
- Prerequisites
- In order to start Diseases of the Immune System lessons, the student should have good knowledge of anatomy and physiopatology and good skill in general phisical examonation of the patient.
- Teaching methods
- the course is organized in the following way:
lecture on all subjects of the course
practices that the students, divided in small groups, they will hold both in ambulatory that in hospital warm - Learning verification modality
- The exam includes a 3 questions. Questions will cover all program topics and can be afforded with a basic knowledge of such topics. The oral exam is open to students who passed the first written test (with a score of at least 18/30) and includes wider questions aimed at evaluating theoretical and practical skills as well as deductive processes and communication. The average examination time is 20-25 minutes.
- Extended program
- Physiology of the human immune system.
The immunodeficiencies:
Pathogenetic mechanisms of infectious risk and diagnostics of immunodeficiencies.
Primary immunodeficiencies:
Severe Combined Immunodeficiencies.
Antibody deficiency diseases.
Complement deficiency diseases
Immunodeficiencies due to granulocyte function deficit
New pathogenetic mechanisms of immune deficiencies and cytopenias
Secondary immunodeficiencies:
AIDS: immuno-pathogenesis, natural history of the disease, main clinical pictures.
Immunodeficiencies due to immunosuppressive and cytostatic drugs
Splenectomy
Immunodeficiencies due to neoplastic diseases
Hematopoietic cell transplantation: basic principles, donor choice,
infectious complications, tolerance and engraftment, graft versus host disease
Antibody and cellular immunotherapy
Principles of immunotherapy of neoplastic and autoimmune diseases
Checkpoint inhibitors
Cellular immunotherapy
Hypersensitivity diseases
Pathophysiology of allergic diseases: hypersensitivity types I, II, III, IV
Immediate hypersensitivity clinical syndromes: Urticaria and angiodema, Food allergies,
Allergic rhinitis, asthma, anaphylactic shock.
Immunological pathogenesis and clinical pictures of the main organ autoimmune diseases
specifications
Hashimoto's thyroiditis
Multiple sclerosis,
autoimmune cytopenias,
aplastic anemia,
Celiac disease
Immune complex diseases and vasculitis:
Purple of the Schonlein-Henoch,
serum sickness,
Cryoglobulinemias
Clinical Immunology of Vaccines
Cognomi M-Z
- CFU
- 2
- Teacher
- Antonio Pierini
- Teachers
- Antonio Pierini
- Hours
- 25 ore - Antonio Pierini
- Language of instruction
- Italian
- Contents
- Physiology of the human immune system.
The immunodeficiencies:
Pathogenetic mechanisms of infectious risk and diagnostics of immunodeficiencies.
Primary immunodeficiencies:
Severe Combined Immunodeficiencies.
Antibody deficiency diseases.
Complement deficiency diseases
Immunodeficiencies due to granulocyte function deficit
New pathogenetic mechanisms of immune deficiencies and cytopenias
Secondary immunodeficiencies:
AIDS: immuno-pathogenesis, natural history of the disease, main clinical pictures.
Immunodeficiencies due to immunosuppressive and cytostatic drugs
Splenectomy
Immunodeficiencies due to neoplastic diseases
Hematopoietic cell transplantation: basic principles, donor choice,
infectious complications, tolerance and engraftment, graft versus host disease
Antibody and cellular immunotherapy
Principles of immunotherapy of neoplastic and autoimmune diseases
Checkpoint inhibitors
Cellular immunotherapy
Hypersensitivity diseases
Pathophysiology of allergic diseases: hypersensitivity types I, II, III, IV
Immediate hypersensitivity clinical syndromes: Urticaria and angiodema, Food allergies,
Allergic rhinitis, asthma, anaphylactic shock.
Immunological pathogenesis and clinical pictures of the main organ autoimmune diseases
specifications
Hashimoto's thyroiditis
Multiple sclerosis,
autoimmune cytopenias,
aplastic anemia,
Celiac disease
Immune complex diseases and vasculitis:
Purple of the Schonlein-Henoch,
serum sickness,
Cryoglobulinemias
Clinical Immunology of Vaccines - Reference texts
- HARRISON " Principles of Internal Medicine"
- Educational objectives
- At the end of the course the student will have to be able to know and to frame, from a clinical and diagnostic point of view , the main diseases of the immunity system., pimary and secondary systemic autoimmunities and immunodeficiency. The verification of the real acquisizioneis of the student will be carried out during examination.
- Prerequisites
- In order to start Diseases of the Immune System lessons, the student should have good knowledge of anatomy and physiopatology and good skill in general phisical examonation of the patient.
- Teaching methods
- the course is organized in the following way:
lecture on all subjects of the course
practices that the students, divided in small groups, they will hold both in ambulatory that in hospital warm - Learning verification modality
- The exam includes a 3 questions. Questions will cover all program topics and can be afforded with a basic knowledge of such topics. The oral exam is open to students who passed the first written test (with a score of at least 18/30) and includes wider questions aimed at evaluating theoretical and practical skills as well as deductive processes and communication. The average examination time is 20-25 minutes.
- Extended program
- Physiology of the human immune system.
The immunodeficiencies:
Pathogenetic mechanisms of infectious risk and diagnostics of immunodeficiencies.
Primary immunodeficiencies:
Severe Combined Immunodeficiencies.
Antibody deficiency diseases.
Complement deficiency diseases
Immunodeficiencies due to granulocyte function deficit
New pathogenetic mechanisms of immune deficiencies and cytopenias
Secondary immunodeficiencies:
AIDS: immuno-pathogenesis, natural history of the disease, main clinical pictures.
Immunodeficiencies due to immunosuppressive and cytostatic drugs
Splenectomy
Immunodeficiencies due to neoplastic diseases
Hematopoietic cell transplantation: basic principles, donor choice,
infectious complications, tolerance and engraftment, graft versus host disease
Antibody and cellular immunotherapy
Principles of immunotherapy of neoplastic and autoimmune diseases
Checkpoint inhibitors
Cellular immunotherapy
Hypersensitivity diseases
Pathophysiology of allergic diseases: hypersensitivity types I, II, III, IV
Immediate hypersensitivity clinical syndromes: Urticaria and angiodema, Food allergies,
Allergic rhinitis, asthma, anaphylactic shock.
Immunological pathogenesis and clinical pictures of the main organ autoimmune diseases
specifications
Hashimoto's thyroiditis
Multiple sclerosis,
autoimmune cytopenias,
aplastic anemia,
Celiac disease
Immune complex diseases and vasculitis:
Purple of the Schonlein-Henoch,
serum sickness,
Cryoglobulinemias
Clinical Immunology of Vaccines
MOLECULAR MEDICINE
| Code | GP004623 |
|---|---|
| CFU | 1 |
| Learning activities | Caratterizzante |
| Area | Fisiopatologia, metodologia clinica, propedeutica clinica e sistematica medico-chirurgica |
| Academic discipline | MED/15 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 1
- Teacher
- Roberta La Starza
- Teachers
- Roberta La Starza
- Hours
- 12.5 ore - Roberta La Starza
- Language of instruction
- Italian
- Contents
- Technological approaches for genome study: cytogenetics, molecular cytogenetics, microarrays, NGS, WET. Leukemic and cancer stem cells, multistep process of oncogenesis; mechanisms of deregulation of oncogenes, oncosuppressors, repair genes and check-point genes.
Hematopietic clonality and pathogenesis of leukemias. Pathogenesis models of congenital and acquired bone marrow failures. Patterns of pathogenesis of acute leukemias. Function of tyrosine kinases. Models of pathogenesis of lymphoproliferative disorders. Models of pathogenesis of myeloma. Patterns of pathogenesis of solid tumors (central nervous system). - Reference texts
- The material will be provided by professor
- Educational objectives
- The course aims to cover the basics of understanding bio-molecular aspects of medicine: mechanisms of gene deregulation, role/function of oncogenes and oncosuppressors, cell cycle, DNA repair mechanisms, germline or acquired alterations, clonal hematopoiesis, preneoplastic clonality
- Prerequisites
- none
- Teaching methods
- Frontal lessons
Seminars - Learning verification modality
- written exam with 15 multiple choice questions; duration 20 minutes
VOTE: Arithmetic mean of grades in individual modules - Extended program
- Technological approaches for genome study: conventional cytogenetics, fluorescence in situ hybridization (interphase, metaphase, on tissue), multi-FISH, arrays on DNA and RNA, NGS targets.
Characteristics of leukemic and cancer stem cell
Study of the multistep process of oncogenesis, mechanisms of alteration of oncogenes, oncosuppressors, repair genes and check-point genes.
Oncogenes and oncosuppressors: role and type of deregulation
Patterns of pathogenesis of congenital and acquired bone marrow failure.
Patterns of pathogenesis of Acute and chronic Leukemias. Function and involvement of tyrosine kinases in human neoplasms.
Pathogenesis models of Multiplo Myeloma and Lymphomas.
Patterns of pathogenesis of solid tumors (central nervous system). - Obiettivi Agenda 2030 per lo sviluppo sostenibile
- 3 - Health and welfare
Cognomi M-Z
- CFU
- 1
- Teacher
- Roberta La Starza
- Teachers
- Roberta La Starza
- Hours
- 12.5 ore - Roberta La Starza
- Language of instruction
- Italian
- Contents
- Technological approaches for genome study: cytogenetics, molecular cytogenetics, microarrays, NGS, WET. Leukemic and cancer stem cells, multistep process of oncogenesis; mechanisms of deregulation of oncogenes, oncosuppressors, repair genes and check-point genes.
Hematopietic clonality and pathogenesis of leukemias. Pathogenesis models of congenital and acquired bone marrow failures. Patterns of pathogenesis of acute leukemias. Function of tyrosine kinases. Models of pathogenesis of lymphoproliferative disorders. Models of pathogenesis of myeloma. Patterns of pathogenesis of solid tumors (central nervous system). - Reference texts
- The material will be provided by professor
- Educational objectives
- The course aims to cover the basics of understanding bio-molecular aspects of medicine: mechanisms of gene deregulation, role/function of oncogenes and oncosuppressors, cell cycle, DNA repair mechanisms, germline or acquired alterations, clonal hematopoiesis, preneoplastic clonality
- Prerequisites
- none
- Teaching methods
- Frontal lessons
Seminars - Learning verification modality
- written exam with 15 multiple choice questions; duration 20 minutes
VOTE: Arithmetic mean of grades in individual modules - Extended program
- Technological approaches for genome study: conventional cytogenetics, fluorescence in situ hybridization (interphase, metaphase, on tissue), multi-FISH, arrays on DNA and RNA, NGS targets.
Characteristics of leukemic and cancer stem cell
Study of the multistep process of oncogenesis, mechanisms of alteration of oncogenes, oncosuppressors, repair genes and check-point genes.
Oncogenes and oncosuppressors: role and type of deregulation
Patterns of pathogenesis of congenital and acquired bone marrow failure.
Patterns of pathogenesis of Acute and chronic Leukemias. Function and involvement of tyrosine kinases in human neoplasms.
Pathogenesis models of Multiplo Myeloma and Lymphomas.
Patterns of pathogenesis of solid tumors (central nervous system). - Obiettivi Agenda 2030 per lo sviluppo sostenibile
- 3 - Health and welfare
REUMATHOLOGY
| Code | GP005657 |
|---|---|
| CFU | 2 |
| Learning activities | Caratterizzante |
| Area | Clinica delle specialità medico-chirurgiche |
| Academic discipline | MED/16 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 2
- Teacher
- Roberto Gerli
- Teachers
- Roberto Gerli
- Giacomo Cafaro (Codocenza)
- Hours
- 20 ore - Roberto Gerli
- 5 ore (Codocenza) - Giacomo Cafaro
- Language of instruction
- ITALIAN
- Contents
- Classification, epidemiology and pathogenesis of rheumatic disease. Clinical features of most common acute and chronic osteoarticular disease, inflammatory and not, of extra-articular rheumatism, of systemic autoimmunitary disease and of systemic vasculitides.
- Reference texts
- REUMATOLOGIA per studenti e Medici di a cura di UNIREUMA. IDELSON GNOCCHI IV Ed. 2022.
HARRISON et al. Principles of Internal Medicine XX Ed. 2021
McGraw Hill Ed. - Educational objectives
- At the end of the Course students are expected to recognize and define the peculiar features of the most common chronic articular conditions, both inflammatory and degenerative, extra-articular rheumatic diseases, systemic autoimmune diseases and systemic vasculitis, from an etiologic, pathogenic and, most importantly, clinical point of view. In addition, the students are asked to prove the ability to recognize and interpret the laboratory tests specific for the aforementioned conditions and the most common instrumental procedures employed in rheumatology clinics. The students’ diagnostic approach based on signs and symptoms will also be evaluated.
- Prerequisites
- In order to start Rheumatology lessons, the student should have good knowledge of anatomy and physiopathology and good skill in general phisical examination of the patient.
- Teaching methods
- The Course includes 25 hours with 14 theoretical hours and 11 hours of practical skills and practical training or seminars.
- Other information
- secretariat Sezione of Reumatologia:
email: sezione.reumatologia@unipg.it
telephone: 075 578.3436 -.3975 - Learning verification modality
- The oral exam includes wider questions aimed at evaluating theoretical and practical skills as well as deductive processes and communication. The average examination time is 20-30 minutes.
- Extended program
- 1. Definition, classification and epidemiology of rheumatic diseases
2. The musculoskeletal system: anatomic and functional elements
3. Etiopathogenic mechanisms of rheumatic diseases
4. Signs and syntoms of rheumatic diseases
5. Laboratory and imaging diagnosis and synovial fluid analysis
6. Inflammatory joint diseases
a) Rheumatoid arthritis and other related joint diseases
b) Spondyloarthritis
i. Ankylosing Spondylitis
ii. Reactive arthritis
iii. Psoriatic arthritis
iv. Enteropathic arthritis
c. Polymyalgia rheumatica
7. Connective tissue diseases
a) Systemic lupus erythematosus
b) Antiphospholipid syndrome
c) Systemic sclerosis
d)Polymyositis/Dermatomyositis/Inflammatory myopathies/Anti-synthetasis antibody syndrome
e) Sjögren's syndrome
f) Overlap syndromes, included mixed connective tissue disesase
g) Undifferentiated connective tissue diseases (UCTD)
8. Primary systemic vasculitides
a) Large size-arteries: Takayasu arteritis, Horton arteritis
b) Medium-size arteries: polyarteritis nodosa
c) Medium and small-size vessels ANCA-associated (micropolyangioitis, granulomatosis with polyangioitis - Wegener's granulomatosis, with eosinophilic granulomatosis with polyangioitis - Churg-Strauss syndrome)
9. Small-size vessels
a) Behçet's disease
b) cryoglobulinemia
c) IgA vasculitis - Schönlein-Henoch purpura
10. Septic and post-infective arthritis (rheumatic fever)
11. Microcrystal arthropaties (Gout, Calcium pyrophosphate dihydrate and hydroxyapatite deposition disorders)
12. Osteoarthritis
13. Localized and generalized extra-articular rheumatic diseases and fibromyalgia
14. Neurovascular and neurologic syndrome
a) Raynaud 's phenomenon
b) Carpal tunnel syndrome
15. Autoinflammatory disorders
a. Adult Still disease
16. Miscellaneous disorders associated with rheumatologic manifestations
a. Sarcoidosis
Cognomi M-Z
- CFU
- 2
- Teacher
- Roberto Gerli
- Teachers
- Elena Bartoloni Bocci (Codocenza)
- Hours
- 25 ore (Codocenza) - Elena Bartoloni Bocci
- Language of instruction
- ITALIAN
- Contents
- Classification, epidemiology and pathogenesis of rheumatic disease. Clinical features of most common acute and chronic osteoarticular disease, inflammatory and not, of extra-articular rheumatism, of systemic autoimmunitary disease and of systemic vasculitides.
- Reference texts
- REUMATOLOGIA per studenti e Medici di a cura di UNIREUMA. IDELSON GNOCCHI IV Ed. 2022.
HARRISON et al. Principles of Internal Medicine XX Ed. 2021.
McGraw Hill Ed. - Educational objectives
- At the end of the Course students are expected to recognize and define the peculiar features of the most common chronic articular conditions, both inflammatory and degenerative, extra-articular rheumatic diseases, systemic autoimmune diseases and systemic vasculitis, from an etiologic, pathogenic and, most importantly, clinical point of view. In addition, the students are asked to prove the ability to recognize and interpret the laboratory tests specific for the aforementioned conditions and the most common instrumental procedures employed in rheumatology clinics. The students’ diagnostic approach based on signs and symptoms will also be evaluated.
- Prerequisites
- In order to start Rheumatology lessons, the student should have good knowledge of anatomy and physiopathology and good skill in general phisical examination of the patient.
- Teaching methods
- The Course includes 25 hours with 14 theoretical hours and 11 hours of practical skills and practical training or seminars.
- Other information
- secretariat Sezione of Reumatologia:
email: sezione.reumatologia@unipg.it
telephone: 075 578.3436 -.3975 - Learning verification modality
- EXAM CONDUCTION METHOD: oral test, lasting on average approximately 15-20 minutes, divided into 2-3 questions relating to topics covered duirng frontal lessons.
TESTING OF CLINICAL SKILLS: the questions are aimed at evaluating theoretical and practical knowledge, as well as reasoning and communication skills.
VERIFICATION OF THE SKILLS ACQUIRED DURING THE INTERNSHIP: a question will concern the differential diagnosis of a clinical rheumatologic condition through the simulation of a clinical case.
METHOD OF ALLOCATION OF THE FINAL MARK: arithmetic mean of the marks obtained in the individual disciplines.
For information on support services for students with disabilities and/or DSA visit the page http://www.unipg.it/disabilita-e-dsa - Extended program
- 1. Definition, classification and epidemiology of rheumatic diseases
2. The musculoskeletal system: anatomic and functional elements
3. Etiopathogenic mechanisms of rheumatic diseases
4. Signs and syntoms of rheumatic diseases
5. Laboratory and imaging diagnosis and synovial fluid analysis
6. Inflammatory joint diseases
a) Rheumatoid arthritis and other related joint diseases
b) Spondyloarthritis
i. Ankylosing Spondylitis
ii. Reactive arthritis
iii. Psoriatic arthritis
iv. Enteropathic arthritis
c. Polymyalgia rheumatica
7. Connective tissue diseases
a) Systemic lupus erythematosus
b) Antiphospholipid syndrome
c) Systemic sclerosis
d)Polymyositis/Dermatomyositis/Inflammatory myopathies/Anti-synthetasis antibody syndrome
e) Sjögren's syndrome
f) Overlap syndromes, included mixed connective tissue disesase
g) Undifferentiated connective tissue diseases (UCTD)
8. Primary systemic vasculitides
a) Large size-arteries: Takayasu arteritis, Horton arteritis
b) Medium-size arteries: polyarteritis nodosa
c) Medium and small-size vessels ANCA-associated (micropolyangioitis, granulomatosis with polyangioitis - Wegener's granulomatosis, with eosinophilic granulomatosis with polyangioitis - Churg-Strauss syndrome)
9. Small-size vessels
a) Behçet's disease
b) cryoglobulinemia
c) IgA vasculitis - Schönlein-Henoch purpura
10. Septic and post-infective arthritis (rheumatic fever)
11. Microcrystal arthropaties (Gout, Calcium pyrophosphate dihydrate and hydroxyapatite deposition disorders)
12. Osteoarthritis
13. Localized and generalized extra-articular rheumatic diseases and fibromyalgia
14. Neurovascular and neurologic syndrome
a) Raynaud 's phenomenon
b) Carpal tunnel syndrome
15. Autoinflammatory disorders
a. Adult Still disease
16. Miscellaneous disorders associated with rheumatologic manifestations
a. Sarcoidosis
b. IgG4-related disease
PROFESSIONALISING TRAINING IN BLOOD DISEASES
| Code | GP004624 |
|---|---|
| CFU | 1 |
| Learning activities | Altro |
| Area | Tirocini formativi e di orientamento |
| Academic discipline | MED/15 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 1
- Teacher
- Maria Paola Martelli
- Teachers
- Maria Paola Martelli
- Hours
- 25 ore - Maria Paola Martelli
- Language of instruction
- Italian
- Contents
- Activities in the outpatient and clinic department with the specialist:
General approach to the patient with alteration of CBC
Discussion of normal and abnormal blood counts:
anemia and erythrocytosis
leucopenie and leukocytosis
thrombocytopenia and thrombocytosis
pancytopenia
General approach to the patient with lymphadenopathy
General approach to the patient with splenomegaly
- Execution, staining and reading the smear of peripheral venous blood (SVP)
- Vision and participation in the examination of the bone marrow: bone marrow aspiration and biopsy procedures - Reference texts
- Harrison's - Principles of Internal Medicine
Hoffbrand/Moss - Essential Haematology
Bosi, De Stefano, Di Raimondo, La Nasa – Manuale di Malattie del Sangue
Avvisati – Ematologia di Mandelli
Hoffman - Hematology basic principles and practice - Educational objectives
- The learning outcomes are compliant with the provisions in the didactic published at: http: //www.med.unipg.it/ccl (http://www.med.unipg.it/ccl)
In detail, the general objective of education is to provide students with the foundation to address the study of blood diseases (either malignant or not).
The main skills that will be acquired:
- Analyze a CBC
- Identify the diagnostic procedure for alterations in the numbers of blood elements
- Identify the diagnostic procedure in case of lymphadenopathy
- Identify the diagnostic procedure in case of splenomegaly - Prerequisites
- Blood Diseases course attendance
- Teaching methods
- Clinic department and laboratory attendance
- Other information
- Hematology Department / Day Hospital - Santa Maria della Misericordia Hospital –Perugia
- Learning verification modality
- Clinical case discussion. Practice test in the department. Discussion on differential diagnosis paths
- Extended program
- Activities in the outpatient and clinic department with the specialist:
General approach to the patient with alteration of CBC
Discussion of normal and abnormal blood counts:
anemia and erythrocytosis
leucopenie and leukocytosis
thrombocytopenia and thrombocytosis
pancytopenia
General approach to the patient with lymphadenopathy
General approach to the patient with splenomegaly
- Execution, staining and reading the smear of peripheral venous blood (SVP)
- Vision and participation in the examination of the bone marrow: bone marrow aspiration and biopsy procedures
Cognomi M-Z
- CFU
- 1
- Teacher
- Maria Paola Martelli
- Teachers
- Maria Paola Martelli
- Hours
- 25 ore - Maria Paola Martelli
- Language of instruction
- Italian
- Contents
- Activities in the outpatient and clinic department with the specialist:
General approach to the patient with alteration of CBC
Discussion of normal and abnormal blood counts:
anemia and erythrocytosis
leucopenie and leukocytosis
thrombocytopenia and thrombocytosis
pancytopenia
General approach to the patient with lymphadenopathy
General approach to the patient with splenomegaly
- Execution, staining and reading the smear of peripheral venous blood (SVP)
- Vision and participation in the examination of the bone marrow: bone marrow aspiration and biopsy procedures - Reference texts
- Harrison's - Principles of Internal Medicine
Hoffbrand/Moss - Essential Haematology
Bosi, De Stefano, Di Raimondo, La Nasa – Manuale di Malattie del Sangue
Avvisati – Ematologia di Mandelli
Hoffman - Hematology basic principles and practice - Educational objectives
- The learning outcomes are compliant with the provisions in the didactic published at: http: //www.med.unipg.it/ccl (http://www.med.unipg.it/ccl)
In detail, the general objective of education is to provide students with the foundation to address the study of blood diseases (either malignant or not).
The main skills that will be acquired:
- Analyze a CBC
- Identify the diagnostic procedure for alterations in the numbers of blood elements
- Identify the diagnostic procedure in case of lymphadenopathy
- Identify the diagnostic procedure in case of splenomegaly - Prerequisites
- Blood Diseases course attendance
- Teaching methods
- Clinic department and laboratory attendance
- Other information
- Hematology Department / Day Hospital - Santa Maria della Misericordia Hospital –Perugia
- Learning verification modality
- Clinical case discussion. Practice test in the department. Discussion on differential diagnosis paths
- Extended program
- Activities in the outpatient and clinic department with the specialist:
General approach to the patient with alteration of CBC
Discussion of normal and abnormal blood counts:
anemia and erythrocytosis
leucopenie and leukocytosis
thrombocytopenia and thrombocytosis
pancytopenia
General approach to the patient with lymphadenopathy
General approach to the patient with splenomegaly
- Execution, staining and reading the smear of peripheral venous blood (SVP)
- Vision and participation in the examination of the bone marrow: bone marrow aspiration and biopsy procedures
PROFESSIONALISING TRAINING IN DISEASES OF THE IMMUNE SYSTEM
| Code | GP005658 |
|---|---|
| CFU | 1 |
| Learning activities | Altro |
| Area | Tirocini formativi e di orientamento |
| Academic discipline | MED/09 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 1
- Teacher
- Antonio Pierini
- Teachers
- Antonio Pierini
- Hours
- 25 ore - Antonio Pierini
- Language of instruction
- Italian
- Contents
- clinical activity with the specialist, in the allogeneic bone marrow transplant department, and allows you to have an almost complete view of infectious complications caused by immunodeficiency states
- Reference texts
- HARRISON " Principles of Internal Medicine
- Educational objectives
- Results based on check of the acquired ability, on the verification of knowledge from a clinical and diagnostic point of view of the main infectious complications caused by states of Immunodeficiencie
- Prerequisites
- For the purpose of learning, the student should have good knowledge of anatomy and physiopathology and good skill in general phisical examination of the patient
- Teaching methods
- Participation in hospital ward activities
- Learning verification modality
- For the professionalizing intership, there is no a specific exam, but this included in the final oral exam.
- Extended program
- clinical activity with the specialist, in the allogeneic bone marrow transplant department, and allows you to have an almost complete view of infectious complications caused by immunodeficiency states
Cognomi M-Z
- CFU
- 1
- Teacher
- Antonio Pierini
- Teachers
- Antonio Pierini
- Hours
- 25 ore - Antonio Pierini
- Language of instruction
- Italian
- Contents
- clinical activity with the specialist, in the allogeneic bone marrow transplant department, and allows you to have an almost complete view of infectious complications caused by immunodeficiency states
- Reference texts
- HARRISON "TRATTATO DI MEDICINA INTERNA"
- Educational objectives
- Results based on check of the acquired ability, on the verification of knowledge from a clinical and diagnostic point of view of the main infectious complications caused by states of Immunodeficiencie
- Prerequisites
- For the purpose of learning, the student should have good knowledge of anatomy and physiopathology and good skill in general phisical examination of the patient.
- Teaching methods
- Participation in hospital ward activities
- Learning verification modality
- For the professionalizing intership, there is no a specific exam, but this included in the final oral exam.
- Extended program
- clinical activity with the specialist, in the allogeneic bone marrow transplant department, and allows you to have an almost complete view of infectious complications caused by immunodeficiency states
PROFESSIONALISING TRAINING IN MOLECULAR MEDICINE
| Code | GP004625 |
|---|---|
| CFU | 1 |
| Learning activities | Altro |
| Area | Tirocini formativi e di orientamento |
| Academic discipline | MED/15 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 1
- Teacher
- Roberta La Starza
- Teachers
- Roberta La Starza
- Hours
- 25 ore - Roberta La Starza
- Language of instruction
- Italian
- Contents
- Technological approaches to genome surveys. Protocols and their applications.
- Educational objectives
- Ability to address diagnostic investigations and optimize procedures.
- Prerequisites
- Knowledge of the genetic basis of tumors.
- Teaching methods
- Tutor system in working groups.
- Learning verification modality
- Verification of learning is done during the internship with questions and direct interaction with the student
- Extended program
- Conventional cytogenetics. FISH, PCR, sequencing. Telomeres, Chromosomal instability test. Test on paraffin sections. Nucleic acids, separation. Microarrays.
- Obiettivi Agenda 2030 per lo sviluppo sostenibile
- 3 - health and welfare
Cognomi M-Z
- CFU
- 1
- Teacher
- Roberta La Starza
- Teachers
- Roberta La Starza
- Hours
- 25 ore - Roberta La Starza
- Language of instruction
- Italian
- Contents
- Technological approaches to genome surveys. Protocols and their applications.
- Educational objectives
- Ability to address diagnostic investigations and optimize procedures.
- Prerequisites
- Knowledge of the genetic basis of tumors.
- Teaching methods
- Tutor system in working groups
- Learning verification modality
- Verification of learning is done during the internship with questions and direct interaction with the student
- Extended program
- Conventional cytogenetics. FISH, PCR, sequencing. Telomeres, Chromosomal instability test. Test on paraffin sections. Nucleic acids, separation. Microarrays.
- Obiettivi Agenda 2030 per lo sviluppo sostenibile
- 3 - health and welfare
PROFESSIONALISING TRAINING IN REUMATHOLOGY
| Code | GP005659 |
|---|---|
| CFU | 1 |
| Learning activities | Altro |
| Area | Tirocini formativi e di orientamento |
| Academic discipline | MED/16 |
| Type of study-unit | Obbligatorio (Required) |
Cognomi A-L
- CFU
- 1
- Teacher
- Roberto Gerli
- Teachers
- Roberto Gerli
- Hours
- 25 ore - Roberto Gerli
- Language of instruction
- Italian
- Contents
- Clinical activity with Rheumatologist, included clinical history, physical examination, diagnosis and therapeutic intervention; infusion of biotechnological agents; instrumental diagnosis by ultrasound evaluation of muscle-skeletal areas and ultrasound-driven interventions for joints, tendons, ...; diagnosis of microcirculation disorders by videocapillaroscopic examination; evaluations of foot and posture disorders.
- Reference texts
- REUMATOLOGIA per studenti e Medici a cura di UNIREUMA. IDELSON GNOCCHI IV Ed. 2022.
HARRISON et al. Principles of Internal Medicine XX Ed. 2021
McGraw Hill Ed. - Educational objectives
- Results based on check of the acquired ability, behavior and interaction degree of the student.
- Prerequisites
- For the purpose of learning, the student should have good knowledge of anatomy and physiopathology and good skill in general phisical examination of the patient.
- Teaching methods
- Partecipation to the above described activities
- Other information
- secretariat Sezione of Reumatologia:
email: sezione.reumatologia@unipg.it
telephone: 075 578.3436 -.3975 - Learning verification modality
- For the professionalizing intership, there is no a specific exam, but this included in the final oral exam.
- Extended program
- 1. Definition, classification and epidemiology of rheumatic diseases
2. The musculoskeletal system: anatomic and functional elements
3. Etiopathogenic mechanisms of rheumatic diseases
4. Signs and syntoms of rheumatic diseases
5. Laboratory and imaging diagnosis and synovial fluid analysis
6. Inflammatory joint diseases
a) Rheumatoid arthritis and other related joint diseases
b) Spondyloarthritis
i. Ankylosing Spondylitis
ii. Reactive arthritis
iii. Psoriatic arthritis
iv. Enteropathic arthritis
c. Polymyalgia rheumatica
7. Connective tissue diseases
a) Systemic lupus erythematosus
b) Antiphospholipid syndrome
c) Systemic sclerosis
d)Polymyositis/Dermatomyositis/Inflammatory myopathies/Anti-synthetasis antibody syndrome
e) Sjögren's syndrome
f) Overlap syndromes, included mixed connective tissue disesase
g) Undifferentiated connective tissue diseases (UCTD)
8. Primary systemic vasculitides
a) Large size-arteries: Takayasu arteritis, Horton arteritis
b) Medium-size arteries: polyarteritis nodosa
c) Medium and small-size vessels ANCA-associated (micropolyangioitis, granulomatosis with polyangioitis - Wegener's granulomatosis, with eosinophilic granulomatosis with polyangioitis - Churg-Strauss syndrome)
9. Small-size vessels
a) Behçet's disease
b) cryoglobulinemia
c) IgA vasculitis - Schönlein-Henoch purpura
10. Septic and post-infective arthritis (rheumatic fever)
11. Microcrystal arthropaties (Gout, Calcium pyrophosphate dihydrate and hydroxyapatite deposition disorders)
12. Osteoarthritis
13. Localized and generalized extra-articular rheumatic diseases and fibromyalgia
14. Neurovascular and neurologic syndrome
a) Raynaud 's phenomenon
b) Carpal tunnel syndrome
15. Autoinflammatory disorders
a. Adult Still disease
16. Miscellaneous disorders associated with rheumatologic manifestations
a. Sarcoidosis
Cognomi M-Z
- CFU
- 1
- Teacher
- Elena Bartoloni Bocci
- Teachers
- Elena Bartoloni Bocci
- Hours
- 25 ore - Elena Bartoloni Bocci
- Language of instruction
- Italian
- Contents
- Clinical activity with Rheumatologist, included clinical history, physical examination, diagnosis and therapeutic intervention; infusion of biotechnological agents; instrumental diagnosis by ultrasound evaluation of muscle-skeletal areas and ultrasound-driven interventions for joints, tendons, ...; diagnosis of microcirculation disorders by videocapillaroscopic examination; evaluations of foot and posture disorders.
- Reference texts
- REUMATOLOGIA per studenti e Medici a cura di UNIREUMA. IDELSON GNOCCHI IV Ed. 2022. HARRISON et al. Principles of Internal Medicine XX Ed. 2021 McGraw Hill Ed.
- Educational objectives
- Results based on check of the acquired ability, behavior and interaction degree of the student.
- Prerequisites
- For the purpose of learning, the student should have good knowledge of anatomy and physiopathology and good skill in general phisical examination of the patient.
- Teaching methods
- Partecipation to the above described activities.
- Other information
- secretariat Sezione of Reumatologia: email: sezione.reumatologia@unipg.it telephone: 075 578.3436 -.3975
- Learning verification modality
- For the professionalizing intership, there is no a specific exam, but this included in the final oral exam.
- Extended program
- 1. Definition, classification and epidemiology of rheumatic diseases
2. The musculoskeletal system: anatomic and functional elements 3. Etiopathogenic mechanisms of rheumatic diseases
4. Signs and syntoms of rheumatic diseases
5. Laboratory and imaging diagnosis and synovial fluid analysis
6. Inflammatory joint diseases
a) Rheumatoid arthritis and other related joint diseases
b) Spondyloarthritis
i. Ankylosing Spondylitis ii. Reactive arthritis iii. Psoriatic arthritis iv. Enteropathic arthritis
c. Polymyalgia rheumatica
7. Connective tissue diseases
a) Systemic lupus erythematosus b) Antiphospholipid syndrome
c) Systemic sclerosis d)Polymyositis/Dermatomyositis/Inflammatory myopathies/Anti-synthetasis antibody syndrome
e) Sjögren's syndrome
f) Overlap syndromes, included mixed connective tissue disesase g) Undifferentiated connective tissue diseases (UCTD)
8. Primary systemic vasculitides
a) Large size-arteries: Takayasu arteritis, Horton arteritis
b) Medium-size arteries: polyarteritis nodosa
c) Medium and small-size vessels ANCA-associated (micropolyangioitis, granulomatosis with polyangioitis - Wegener's granulomatosis, with eosinophilic granulomatosis with polyangioitis - Churg-Strauss syndrome)
9. Small-size vessels a) Behçet's disease b) cryoglobulinemia c) IgA vasculitis - Schönlein-Henoch purpura
10. Septic and post-infective arthritis (rheumatic fever)
11. Microcrystal arthropaties (Gout, Calcium pyrophosphate dihydrate and hydroxyapatite deposition disorders)
12. Osteoarthritis
13. Localized and generalized extra-articular rheumatic diseases and fibromyalgia
14. Neurovascular and neurologic syndrome a) Raynaud 's phenomenon b) Carpal tunnel syndrome
15. Autoinflammatory disorders
a. Adult Still disease
16. Miscellaneous disorders associated with rheumatologic manifestations
a. Sarcoidosis
b. IgG4 related disease