Unit NMR TECHNIQUES IN PHYSIOLOGY AND MEDICINE
- Course
- Physics
- Study-unit Code
- A002576
- Location
- PERUGIA
- Curriculum
- Fisica medica
- Teacher
- Roberto Tarducci
- Teachers
-
- Roberto Tarducci
- Hours
- 42 ore - Roberto Tarducci
- CFU
- 6
- Course Regulation
- Coorte 2022
- Offered
- 2022/23
- Learning activities
- Affine/integrativa
- Area
- Attività formative affini o integrative
- Academic discipline
- FIS/07
- Type of study-unit
- Opzionale (Optional)
- Type of learning activities
- Attività formativa monodisciplinare
- Language of instruction
- Italian
- Contents
- 1. Classical description of NMR;
2. Density matrix description of NMR;
3. Pulsed NMR
4. Applications - Reference texts
- MH Levitt - Spin Dynamics Basics of Nuclear Magnetic Resonance (2nd edition) Wiley (2008);
C Costantinides "Magnetic Resonace Imaging - the basic" CRC Press (2014) - Educational objectives
- To understand theoretical description of NMR phenomenon and its medical applications.
The application will concern:
1. NMR spectroscopy in vivo;
2. study of the cerebral activation of the motor areas;
3. measurement of the brain water diffusion tensor. - Prerequisites
- Statistical physics, quantum mechanics, classical electrodynamics
- Teaching methods
- interactive lesson
- Learning verification modality
- required to pass an oral examination
- Extended program
- 1) Physical foundations of magnetic resonance imaging
a. Treatment of the physical foundations of magnetic resonance imaging;
b. Structure of an NMR scanner for clinical use;
(10 lessons)
2) Biophysical aspects of nuclear spin relaxation
a. Relaxation mechanisms;
b. Contrasts in T1, T2 and proton density;
c. Paramagnetic contrast media.
(2 lessons)
3) Reconstruction of magnetic resonance images
a. Magnetic field gradients and slice selection;
b. Phase and frequency encoding;
c. Trajectories in space k;
d. Spin echo sequence;
e. Images based on the gradient echo;
f. Bloch equation simulation.
(7 lessons)