Unit PHARMACOLOGY

Course
Medicine and surgery
Study-unit Code
GP004550
Curriculum
In all curricula
Teacher
Graziella Migliorati
CFU
13
Course Regulation
Coorte 2020
Offered
2023/24
Type of study-unit
Obbligatorio (Required)
Type of learning activities
Attività formativa integrata

PHARMACOLOGY - MOD. 1

Code GP004575
CFU 3
Teacher Graziella Migliorati
Learning activities Caratterizzante
Area Farmacologia, tossicologia e principi di terapia medica
Academic discipline BIO/14
Type of study-unit Obbligatorio (Required)

Cognomi A-L

CFU
3
Teacher
Graziella Migliorati
Teachers
  • Graziella Migliorati
Hours
  • 37.5 ore - Graziella Migliorati
Language of instruction
Italian
Contents
General principles

Pharmacokinetics

Pharmacodynamics

Molecular mechanisms of drug action

Principles of clinical pharmacology and therapy

Autonomic nervous system phramacology
Reference texts
Reccomended reading:
- F. Rossi, V. Cuomo, C. Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, V Edizione, Edizioni Minerva Medica
- B.G. Katzung, A.J. Trevor, Farmacologia generale e clinica, XI edizione, PICCIN

Reference books:
- A. Goodman & Gilman, Le basi farmacologiche della terapia, XIII edizione, Zanichelli
- F. Clementi, G. Fumagalli, Farmacologia generale e molecolare, V edizione, Edra
Educational objectives
At the end of the course students will have learned the pharmacodynamics, pharmacokinetics, undesirable side effects, toxicological aspects, the therapeutic foundations and methods of administration of drugs most important in medical practice.
Should be aware of the factors that influence the pharmacological effect and / or therapeutic, as well as the risk / benefit ratio of drug therapy.
Must know how to make a reasoned choice of drugs in relation to different pathological situations.
Prerequisites
In order to achieve the intended learning outcomes, the student must have a solid background in anatomy, physiology and general pathology. The student must have already passed the other exams considered as preparatory by the Academic Regulations.
Teaching methods
Lectures
Mandatory attendence
Other information
Attendance to the lectures plays an important role in the learning process as a guide to the critical reading of teaching material made available in electronic format through the institutional platform.
The consultation of the material presented during the lectures does not replace the study of textbooks. The teachers deny consent to disseminate in any form the possible recording of the lessons.
Learning verification modality
Written exam and oral exam

The test focuses globally on the entire program.

The test consists of 62 multiple choice quiz with five possible answers of which only one is correct;
The exam duration time is 1 hour and 15 minutes.

For the evaluation of the test takes into account the following criteria:
- 0.5 points for each correct answer;
- Less than 0.1 points for each wrong answer;
- 0 points for each question not answered;

The written exam is passed if for each test is obtained a score of at least 18/30.

The oral test is mandatory, concerns topics of the entire program and is primarily designed to evaluate the ability to apply their knowledge for the proper use of the drugs in clinical practice.

Final vote accounts for 40% of the vote overall written test and 60% vote of the oral test.
Extended program
General principles

Origin and Drug Classification

Pharmacokinetics
Routes of administration
Absorption, bioavailability
Distribution
Metabolism
Elimination
Main pharmacokinetic parameters: volume of distribution, half-life, clearance
Pharmacokinetics quantitative kinetics of zero order and first order
Clinical pharmacokinetics, kinetics of the drug administered in repeated doses, the concept of steady state

Pharmacodynamics
Drug-drug interaction recetthours
Agonists, antagonists, partial agonists and inverse
Dose-response curves and curves quantal
Affinity, potency, efficacy, therapeutic index
Molecular structure of receptors
Mechanisms of signal transduction
Regulation of receptor response
Mechanism of action of drugs and correlation between concentration and pharmacological effect of drugs
Principles of clinical pharmacology and therapy
Adverse drug reaction
Variability in individual response to drugs: pharmacokinetic and pharmacodynamic variables, tolerance
Pharmacogenetics
Drug interactions

Drugs acting at synaptic and neuroeffector junctions
Neurohumoral transmission: the autonomic and somatic motor
Cholinergic Agonists
Anticholinesterases
Muscarinic antagonists
Drugs acting on the neuromuscular junction and autonomic ganglia
Catecholamines and sympathomimetic drugs
Adrenergic neuron antagonist

Cognomi M-Z

CFU
3
Teacher
Graziella Migliorati
Teachers
  • Graziella Migliorati
Hours
  • 37.5 ore - Graziella Migliorati
Language of instruction
Italian
Contents
General principles

Pharmacokinetics

Pharmacodynamics

Molecular mechanisms of drug action

Principles of clinical pharmacology and therapy

Autonomic nervous system phramacology
Reference texts
Reccomended reading:
- F. Rossi, V. Cuomo, C. Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, V Edizione, Edizioni Minerva Medica
- B.G. Katzung, A.J. Trevor, Farmacologia generale e clinica, XI edizione, PICCIN

Reference books:
- A. Goodman & Gilman, Le basi farmacologiche della terapia, XIII edizione, Zanichelli
- F. Clementi, G. Fumagalli, Farmacologia generale e molecolare, V edizione, Edra
Educational objectives
At the end of the course students will have learned the pharmacodynamics, pharmacokinetics, undesirable side effects, toxicological aspects, the therapeutic foundations and methods of administration of drugs most important in medical practice.
Should be aware of the factors that influence the pharmacological effect and / or therapeutic, as well as the risk / benefit ratio of drug therapy.
Must know how to make a reasoned choice of drugs in relation to different pathological situations.
Prerequisites
In order to achieve the intended learning outcomes, the student must have a solid background in anatomy, physiology and general pathology. The student must have already passed the other exams considered as preparatory by the Academic Regulations.
Teaching methods
Lectures
Mandatory attendence
Other information
Attendance to the lectures plays an important role in the learning process as a guide to the critical reading of teaching material made available in electronic format through the institutional platform.
The consultation of the material presented during the lectures does not replace the study of textbooks. The teachers deny consent to disseminate in any form the possible recording of the lessons.
Learning verification modality
Written exam and oral exam

The test focuses globally on the entire program.

The test consists of 62 multiple choice quiz with five possible answers of which only one is correct;
The exam duration time is 1 hour and 15 minutes.

For the evaluation of the test takes into account the following criteria:
- 0.5 points for each correct answer;
- Less than 0.1 points for each wrong answer;
- 0 points for each question not answered;

The written exam is passed if for each test is obtained a score of at least 18/30.

The oral test is mandatory, concerns topics of the entire program and is primarily designed to evaluate the ability to apply their knowledge for the proper use of the drugs in clinical practice.

Final vote accounts for 40% of the vote overall written test and 60% vote of the oral test.
Extended program
General principles

Origin and Drug Classification

Pharmacokinetics
Routes of administration
Absorption, bioavailability
Distribution
Metabolism
Elimination
Main pharmacokinetic parameters: volume of distribution, half-life, clearance
Pharmacokinetics quantitative kinetics of zero order and first order
Clinical pharmacokinetics, kinetics of the drug administered in repeated doses, the concept of steady state

Pharmacodynamics
Drug-drug interaction recetthours
Agonists, antagonists, partial agonists and inverse
Dose-response curves and curves quantal
Affinity, potency, efficacy, therapeutic index
Molecular structure of receptors
Mechanisms of signal transduction
Regulation of receptor response
Mechanism of action of drugs and correlation between concentration and pharmacological effect of drugs
Principles of clinical pharmacology and therapy
Adverse drug reaction
Variability in individual response to drugs: pharmacokinetic and pharmacodynamic variables, tolerance
Pharmacogenetics
Drug interactions

Drugs acting at synaptic and neuroeffector junctions
Neurohumoral transmission: the autonomic and somatic motor
Cholinergic Agonists
Anticholinesterases
Muscarinic antagonists
Drugs acting on the neuromuscular junction and autonomic ganglia
Catecholamines and sympathomimetic drugs
Adrenergic neuron antagonist

PHARMACOLOGY - MOD. 2

Code GP004576
CFU 3
Teacher Graziella Migliorati
Learning activities Caratterizzante
Area Farmacologia, tossicologia e principi di terapia medica
Academic discipline BIO/14
Type of study-unit Obbligatorio (Required)

Cognomi A-L

CFU
3
Teacher
Graziella Migliorati
Teachers
  • Graziella Migliorati
Hours
  • 37.5 ore - Graziella Migliorati
Language of instruction
Italian
Contents
Cardiovascular system drugs
Drugs acting on blood and blood-forming organs
Reference texts
Reccomended reading:
- F. Rossi, V. Cuomo, C. Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, V Edizione, Edizioni Minerva Medica
- B.G. Katzung, A.J. Trevor, Farmacologia generale e clinica, XI edizione, PICCIN

Reference books:
- A. Goodman & Gilman, Le basi farmacologiche della terapia, XIII edizione, Zanichelli
- F. Clementi, G. Fumagalli, Farmacologia generale e molecolare, V edizione, Edra
Educational objectives
At the end of the course students will have learned the pharmacodynamics, pharmacokinetics, undesirable side effects, toxicological aspects, the therapeutic foundations and methods of administration of drugs most important in medical practice.
Should be aware of the factors that influence the pharmacological effect and / or therapeutic, as well as the risk / benefit ratio of drug therapy.
Must know how to make a reasoned choice of drugs in relation to different pathological situations.
Prerequisites
In order to achieve the intended learning outcomes, the student must have a solid background in anatomy, physiology and general pathology. The student must have already passed the other exams considered as preparatory by the Academic Regulations.
Teaching methods
Lectures
Mandatory attendence
Other information
Attendance to the lectures plays an important role in the learning process as a guide to the critical reading of teaching material made available in electronic format through the institutional platform.
The consultation of the material presented during the lectures does not replace the study of textbooks. The teachers deny consent to disseminate in any form the possible recording of the lessons.
Learning verification modality
Written exam and oral exam

The test focuses globally on the entire program.

The test consists of 62 multiple choice quiz with five possible answers of which only one is correct;
The exam duration time is 1 hour and 15 minutes.

For the evaluation of the test takes into account the following criteria:
- 0.5 points for each correct answer;
- Less than 0.1 points for each wrong answer;
- 0 points for each question not answered;

The written exam is passed if for each test is obtained a score of at least 18/30.

The oral test is mandatory, concerns topics of the entire program and is primarily designed to evaluate the ability to apply their knowledge for the proper use of the drugs in clinical practice.

Final vote accounts for 40% of the vote overall written test and 60% vote of the oral test.
Extended program
Cardiovascular system drugs
Drugs that affect renal function and electrolyte metabolism
Pharmacological control of the renin-angiotensin-aldosterone
Antihypertensive drugs
Antianginal drugs
Cardiac glycosides
Antiarrhythmic drugs
Drugs for treatment of dyslipidemia
Drugs acting on blood and blood-forming organs
hematopoietic agents: growth factors and vitamins
Anticoagulant, thrombolytic and antiplatelet drugs

Cognomi M-Z

CFU
3
Teacher
Graziella Migliorati
Teachers
  • Graziella Migliorati
Hours
  • 37.5 ore - Graziella Migliorati
Language of instruction
Italian
Contents
Cardiovascular system drugs
Drugs acting on blood and blood-forming organs
Reference texts
Reccomended reading:
- F. Rossi, V. Cuomo, C. Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, V Edizione, Edizioni Minerva Medica
- B.G. Katzung, A.J. Trevor, Farmacologia generale e clinica, XI edizione, PICCIN

Reference books:
- A. Goodman & Gilman, Le basi farmacologiche della terapia, XIII edizione, Zanichelli
- F. Clementi, G. Fumagalli, Farmacologia generale e molecolare, V edizione, Edra
Educational objectives
At the end of the course students will have learned the pharmacodynamics, pharmacokinetics, undesirable side effects, toxicological aspects, the therapeutic foundations and methods of administration of drugs most important in medical practice.
Should be aware of the factors that influence the pharmacological effect and / or therapeutic, as well as the risk / benefit ratio of drug therapy.
Must know how to make a reasoned choice of drugs in relation to different pathological situations.
Prerequisites
In order to achieve the intended learning outcomes, the student must have a solid background in anatomy, physiology and general pathology. The student must have already passed the other exams considered as preparatory by the Academic Regulations.
Teaching methods
Lectures
Mandatory attendence
Other information
Attendance to the lectures plays an important role in the learning process as a guide to the critical reading of teaching material made available in electronic format through the institutional platform.
The consultation of the material presented during the lectures does not replace the study of textbooks. The teachers deny consent to disseminate in any form the possible recording of the lessons.
Learning verification modality
Written exam and oral exam

The test focuses globally on the entire program.

The test consists of 62 multiple choice quiz with five possible answers of which only one is correct;
The exam duration time is 1 hour and 15 minutes.

For the evaluation of the test takes into account the following criteria:
- 0.5 points for each correct answer;
- Less than 0.1 points for each wrong answer;
- 0 points for each question not answered;

The written exam is passed if for each test is obtained a score of at least 18/30.

The oral test is mandatory, concerns topics of the entire program and is primarily designed to evaluate the ability to apply their knowledge for the proper use of the drugs in clinical practice.

Final vote accounts for 40% of the vote overall written test and 60% vote of the oral test.
Extended program
Cardiovascular system drugs
Drugs that affect renal function and electrolyte metabolism
Pharmacological control of the renin-angiotensin-aldosterone
Antihypertensive drugs
Antianginal drugs
Cardiac glycosides
Antiarrhythmic drugs
Drugs for treatment of dyslipidemia
Drugs acting on blood and blood-forming organs
hematopoietic agents: growth factors and vitamins
Anticoagulant, thrombolytic and antiplatelet drugs

PHARMACOLOGY - MOD. 3

Code GP004577
CFU 3
Teacher Graziella Migliorati
Learning activities Caratterizzante
Area Farmacologia, tossicologia e principi di terapia medica
Academic discipline BIO/14
Type of study-unit Obbligatorio (Required)

Cognomi A-L

CFU
3
Teacher
Graziella Migliorati
Teachers
  • Graziella Migliorati
  • Domenico Vittorio Delfino
Hours
  • 25 ore - Graziella Migliorati
  • 15 ore - Domenico Vittorio Delfino
Language of instruction
Italian
Contents
Drugs acting on the central nervous system
Autacoids and anti-inflammatory drugs
Drugs that affect gastrointestinal function
Pharmacology of the immune system
Reference texts
Reccomended reading:
- F. Rossi, V. Cuomo, C. Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, V Edizione, Edizioni Minerva Medica
- B.G. Katzung, A.J. Trevor, Farmacologia generale e clinica, XI edizione, PICCIN

Reference books:
- A. Goodman & Gilman, Le basi farmacologiche della terapia, XIII edizione, Zanichelli
- F. Clementi, G. Fumagalli, Farmacologia generale e molecolare, V edizione, Edra
Educational objectives
At the end of the course students will have learned the pharmacodynamics, pharmacokinetics, undesirable side effects, toxicological aspects, the therapeutic foundations and methods of administration of drugs most important in medical practice.
Should be aware of the factors that influence the pharmacological effect and / or therapeutic, as well as the risk / benefit ratio of drug therapy.
Must know how to make a reasoned choice of drugs in relation to different pathological situations.
Prerequisites
In order to achieve the intended learning outcomes, the student must have a solid background in anatomy, physiology and general pathology. The student must have already passed the other exams considered as preparatory by the Academic Regulations.
Teaching methods
Lectures
Mandatory attendence
Other information
Attendance to the lectures plays an important role in the learning process as a guide to the critical reading of teaching material made available in electronic format through the institutional platform.
The consultation of the material presented during the lectures does not replace the study of textbooks. The teachers deny consent to disseminate in any form the possible recording of the lessons.
Learning verification modality
Written exam and oral exam

The test focuses globally on the entire program.

The test consists of 62 multiple choice quiz with five possible answers of which only one is correct;
The exam duration time is 1 hour and 15 minutes.

For the evaluation of the test takes into account the following criteria:
- 0.5 points for each correct answer;
- Less than 0.1 points for each wrong answer;
- 0 points for each question not answered;

The written exam is passed if for each test is obtained a score of at least 18/30.

The oral test is mandatory, concerns topics of the entire program and is primarily designed to evaluate the ability to apply their knowledge for the proper use of the drugs in clinical practice.

Final vote accounts for 40% of the vote overall written test and 60% vote of the oral test.
Extended program
Drugs acting on the central nervous system
Neurotransmission and the central nervous system
Anxiolytics and sedative-hypnotics
Drugs of Affective Disorders, antipsychotics, antidepressants
Drugs for the treatment of migraine and the control of vomiting
Pharmacology of analgesia
General Anesthetics
Anticonvulsants
Drugs for treatment of neurodegenerative diseases
Pharmacology of drugs of abuse


Autacoids and anti-inflammatory drugs
General information on inflammation and mediators involved
Histamine and antihistamines
Non-steroidal anti-inflammatory drugs, drugs used in the treatment of rheumatoid arthritis and gout
Steroidal anti-inflammatory drugs
Drugs used to treat asthma

Drugs that affect gastrointestinal function
Antiulcer drugs
Drugs that affect gastrointestinal motility

Pharmacology of the immune system
Serums and Vaccines
Immunosuppressants and immunostimulants

Cognomi M-Z

CFU
3
Teacher
Graziella Migliorati
Teachers
  • Graziella Migliorati
  • Domenico Vittorio Delfino
Hours
  • 25 ore - Graziella Migliorati
  • 15 ore - Domenico Vittorio Delfino
Language of instruction
Italian
Contents
Drugs acting on the central nervous system
Autacoids and anti-inflammatory drugs
Drugs that affect gastrointestinal function
Pharmacology of the immune system
Reference texts
Reccomended reading:
- F. Rossi, V. Cuomo, C. Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, V Edizione, Edizioni Minerva Medica
- B.G. Katzung, A.J. Trevor, Farmacologia generale e clinica, XI edizione, PICCIN

Reference books:
- A. Goodman & Gilman, Le basi farmacologiche della terapia, XIII edizione, Zanichelli
- F. Clementi, G. Fumagalli, Farmacologia generale e molecolare, V edizione, Edra
Educational objectives
At the end of the course students will have learned the pharmacodynamics, pharmacokinetics, undesirable side effects, toxicological aspects, the therapeutic foundations and methods of administration of drugs most important in medical practice.
Should be aware of the factors that influence the pharmacological effect and / or therapeutic, as well as the risk / benefit ratio of drug therapy.
Must know how to make a reasoned choice of drugs in relation to different pathological situations.
Prerequisites
In order to achieve the intended learning outcomes, the student must have a solid background in anatomy, physiology and general pathology. The student must have already passed the other exams considered as preparatory by the Academic Regulations.
Teaching methods
Lectures
Mandatory attendence
Other information
Attendance to the lectures plays an important role in the learning process as a guide to the critical reading of teaching material made available in electronic format through the institutional platform.
The consultation of the material presented during the lectures does not replace the study of textbooks. The teachers deny consent to disseminate in any form the possible recording of the lessons.
Learning verification modality
Written exam and oral exam

The test focuses globally on the entire program.

The test consists of 62 multiple choice quiz with five possible answers of which only one is correct;
The exam duration time is 1 hour and 15 minutes.

For the evaluation of the test takes into account the following criteria:
- 0.5 points for each correct answer;
- Less than 0.1 points for each wrong answer;
- 0 points for each question not answered;

The written exam is passed if for each test is obtained a score of at least 18/30.

The oral test is mandatory, concerns topics of the entire program and is primarily designed to evaluate the ability to apply their knowledge for the proper use of the drugs in clinical practice.

Final vote accounts for 40% of the vote overall written test and 60% vote of the oral test.
Extended program
Drugs acting on the central nervous system
Neurotransmission and the central nervous system
Anxiolytics and sedative-hypnotics
Drugs of Affective Disorders, antipsychotics, antidepressants
Drugs for the treatment of migraine and the control of vomiting
Pharmacology of analgesia
General Anesthetics
Anticonvulsants
Drugs for treatment of neurodegenerative diseases
Pharmacology of drugs of abuse


Autacoids and anti-inflammatory drugs
General information on inflammation and mediators involved
Histamine and antihistamines
Non-steroidal anti-inflammatory drugs, drugs used in the treatment of rheumatoid arthritis and gout
Steroidal anti-inflammatory drugs
Drugs used to treat asthma

Drugs that affect gastrointestinal function
Antiulcer drugs
Drugs that affect gastrointestinal motility

Pharmacology of the immune system
Serums and Vaccines
Immunosuppressants and immunostimulants

PHARMACOLOGY - MOD. 4

Code A001684
CFU 3
Teacher Graziella Migliorati
Learning activities Caratterizzante
Area Formazione clinica interdisciplinare e medicina basata sulle evidenze
Academic discipline BIO/14
Type of study-unit Obbligatorio (Required)

Cognomi A-L

CFU
3
Teacher
Giuseppe Nocentini
Teachers
  • Graziella Migliorati (Codocenza)
  • Emira Maria Ayroldi (Codocenza)
Hours
  • 25 ore (Codocenza) - Graziella Migliorati
  • 12.5 ore (Codocenza) - Emira Maria Ayroldi
Language of instruction
Italian
Contents
Endocrine Drugs

Drugs affecting uterine motility

Chemotherapy
Reference texts
Reccomended reading:
- F. Rossi, V. Cuomo, C. Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, V Edizione, Edizioni Minerva Medica
- B.G. Katzung, A.J. Trevor, Farmacologia generale e clinica, XI edizione, PICCIN

Reference books:
- A. Goodman & Gilman, Le basi farmacologiche della terapia, XIII edizione, Zanichelli
- F. Clementi, G. Fumagalli, Farmacologia generale e molecolare, V edizione, Edra
Educational objectives
At the end of the course students will have learned the pharmacodynamics, pharmacokinetics, undesirable side effects, toxicological aspects, the therapeutic foundations and methods of administration of drugs most important in medical practice.
Should be aware of the factors that influence the pharmacological effect and / or therapeutic, as well as the risk / benefit ratio of drug therapy.
Must know how to make a reasoned choice of drugs in relation to different pathological situations.
Prerequisites
In order to achieve the intended learning outcomes, the student must have a solid background in anatomy, physiology and general pathology. The student must have already passed the other exams considered as preparatory by the Academic Regulations.
Teaching methods
Lectures
Mandatory attendence
Other information
Attendance to the lectures plays an important role in the learning process as a guide to the critical reading of teaching material made available in electronic format through the institutional platform.
The consultation of the material presented during the lectures does not replace the study of textbooks. The teachers deny consent to disseminate in any form the possible recording of the lessons.
Learning verification modality
Written exam and oral exam

The test focuses globally on the entire program.

The test consists of 62 multiple choice quiz with five possible answers of which only one is correct;
The exam duration time is 1 hour and 15 minutes.

For the evaluation of the test takes into account the following criteria:
- 0.5 points for each correct answer;
- Less than 0.1 points for each wrong answer;
- 0 points for each question not answered;

The written exam is passed if for each test is obtained a score of at least 18/30.

The oral test is mandatory, concerns topics of the entire program and is primarily designed to evaluate the ability to apply their knowledge for the proper use of the drugs in clinical practice.

Final vote accounts for 40% of the vote overall written test and 60% vote of the oral test.
Extended program
Endocrine Drugs
Thyroid and Antithyroid
Estrogens, progestins, birth control
Androgens and anabolic steroids
Insulin and oral hypoglycemic

Drugs affecting uterine motility
Chemotherapy
General principles
Antibacterial chemotherapy:
Drugs inhibiting cell wall synthesis
Drugs inhibiting protein synthesis
Fluoroquinolones
Sulfonamides and trimethoprim
Metronidazole
Anti-tuberculosis
Antiprotozoal chemotherapy
Antiviral chemotherapy
Antifungal chemotherapy
Antineoplastic chemotherapy

Cognomi M-Z

CFU
3
Teacher
Giuseppe Nocentini
Teachers
  • Graziella Migliorati (Codocenza)
  • Giuseppe Nocentini
Hours
  • 12.5 ore (Codocenza) - Graziella Migliorati
  • 25 ore - Giuseppe Nocentini
Language of instruction
Italian
Contents
Endocrine Drugs

Drugs affecting uterine motility

Chemotherapy
Reference texts
Reccomended reading:
- F. Rossi, V. Cuomo, C. Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, V Edizione, Edizioni Minerva Medica
- B.G. Katzung, A.J. Trevor, Farmacologia generale e clinica, XI edizione, PICCIN

Reference books:
- A. Goodman & Gilman, Le basi farmacologiche della terapia, XIII edizione, Zanichelli
- F. Clementi, G. Fumagalli, Farmacologia generale e molecolare, V edizione, Edra
Educational objectives
At the end of the course students will have learned the pharmacodynamics, pharmacokinetics, undesirable side effects, toxicological aspects, the therapeutic foundations and methods of administration of drugs most important in medical practice.
Should be aware of the factors that influence the pharmacological effect and / or therapeutic, as well as the risk / benefit ratio of drug therapy.
Must know how to make a reasoned choice of drugs in relation to different pathological situations.
Prerequisites
In order to achieve the intended learning outcomes, the student must have a solid background in anatomy, physiology and general pathology. The student must have already passed the other exams considered as preparatory by the Academic Regulations.
Teaching methods
Lectures
Mandatory attendence
Other information
Attendance to the lectures plays an important role in the learning process as a guide to the critical reading of teaching material made available in electronic format through the institutional platform.
The consultation of the material presented during the lectures does not replace the study of textbooks. The teachers deny consent to disseminate in any form the possible recording of the lessons.
Learning verification modality
Written exam and oral exam

The test focuses globally on the entire program.

The test consists of 62 multiple choice quiz with five possible answers of which only one is correct;
The exam duration time is 1 hour and 15 minutes.

For the evaluation of the test takes into account the following criteria:
- 0.5 points for each correct answer;
- Less than 0.1 points for each wrong answer;
- 0 points for each question not answered;

The written exam is passed if for each test is obtained a score of at least 18/30.

The oral test is mandatory, concerns topics of the entire program and is primarily designed to evaluate the ability to apply their knowledge for the proper use of the drugs in clinical practice.

Final vote accounts for 40% of the vote overall written test and 60% vote of the oral test.
Extended program
Endocrine Drugs
Thyroid and Antithyroid
Estrogens, progestins, birth control
Androgens and anabolic steroids
Insulin and oral hypoglycemic

Drugs affecting uterine motility
Chemotherapy
General principles
Antibacterial chemotherapy:
Drugs inhibiting cell wall synthesis
Drugs inhibiting protein synthesis
Fluoroquinolones
Sulfonamides and trimethoprim
Metronidazole
Anti-tuberculosis
Antiprotozoal chemotherapy
Antiviral chemotherapy
Antifungal chemotherapy
Antineoplastic chemotherapy

PHARMACOLOGY - MOD. 5

Code A001685
CFU 1
Teacher Graziella Migliorati
Learning activities Affine/integrativa
Area Attività formative affini o integrative
Academic discipline BIO/14
Type of study-unit Obbligatorio (Required)

Cognomi A-L

CFU
1
Teacher
Stefano Bruscoli
Teachers
  • Stefano Bruscoli
Hours
  • 12.5 ore - Stefano Bruscoli
Language of instruction
Italian
Contents
Toxicology
Pharmacological trials
Gender pharmacology
Reference texts
Recommended reading:
- F. Rossi, V. Cuomo, C. Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, V Edizione, Edizioni Minerva Medica
- F. Clementi, G. Fumagalli, Farmacologia generale e molecolare, V edizione, UTET
- B.G. Satzung, A.J. Trevor, Farmacologia general and clinical pharmacology, PICCIN, XI edition
Reference books:
- A. Goodman & Gilman, Le basi farmacologiche della terapia, XIII edizione, Zanichelli
Educational objectives
See module 1
Prerequisites
In order to achieve the intended learning outcomes, the student must have a solid background in anatomy, physiology and general pathology. The student must have already passed the other exams considered as preparatory by the Academic Regulations.
Teaching methods
Lessons face-to-face Mandatory attendence
Other information
See module 1
Learning verification modality
Written exam and oral exam
The test focuses globally on the entire program.
The test consists of 62 multiple choice quiz with five possible answers of which only one is correct;
The exam duration time is 1 hour and 15 minutes.
For the evaluation of the test takes into account the following criteria: - 0.5 points for each correct answer;
- Less than 0.1 points for each wrong answer;
- 0 points for each question not answered;
The written exam is passed if for each test is obtained a score of at least 18/30.
The oral test is mandatory, concerns topics of the entire program and is primarily designed to evaluate the ability to apply their knowledge for the proper use of the drugs in clinical practice.
Final vote accounts for 40% of the vote overall written test and 60% vote of the oral test.
Extended program
Toxicology
Principles of Toxicology
Mechanisms of toxicity
Fetotoxicity
Pharmacological trials, pharmacovigilance Gender pharmacology
Equivalent medicines
Biological drugs and biosimilar products
Obiettivi Agenda 2030 per lo sviluppo sostenibile

Cognomi M-Z

CFU
1
Teacher
Simona Ronchetti
Teachers
  • Simona Ronchetti
Hours
  • 12.5 ore - Simona Ronchetti
Language of instruction
Italian
Contents
Drugs acting on the central nervous system

Endocrine Drugs

Drugs affecting uterine motility

Chemotherapy
Reference texts
Reccomended reading:
- F. Rossi, V. Cuomo, C. Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, IV Edizione, Edizioni Minerva Medica
- B.G. Katzung, A.J. Trevor, Farmacologia generale e clinica, XI edizione, PICCIN

Reference books:
- A. Goodman & Gilman, Le basi farmacologiche della terapia, XIII edizione, Zanichelli
- F. Clementi, G. Fumagalli, Farmacologia generale e molecolare, V edizione, Edra
Educational objectives
At the end of the course students will have learned the pharmacodynamics, pharmacokinetics, undesirable side effects, toxicological aspects, the therapeutic foundations and methods of administration of drugs most important in medical practice.
Should be aware of the factors that influence the pharmacological effect and / or therapeutic, as well as the risk / benefit ratio of drug therapy.
Must know how to make a reasoned choice of drugs in relation to different pathological situations.
Prerequisites
In order to achieve the intended learning outcomes, the student must have a solid background in anatomy, physiology and general pathology. The student must have already passed the other exams considered as preparatory by the Academic Regulations.
Teaching methods
Lectures
Mandatory attendence
Other information
Attendance to the lectures plays an important role in the learning process as a guide to the critical reading of teaching material made available in electronic format through the institutional platform.
The consultation of the material presented during the lectures does not replace the study of textbooks. The teachers deny consent to disseminate in any form the possible recording of the lessons.
Learning verification modality
Written exam and oral exam

The test focuses globally on the entire program.

The test consists of 62 multiple choice quiz with five possible answers of which only one is correct;
The exam duration time is 1 hour and 15 minutes.

For the evaluation of the test takes into account the following criteria:
- 0.5 points for each correct answer;
- Less than 0.1 points for each wrong answer;
- 0 points for each question not answered;

The written exam is passed if for each test is obtained a score of at least 18/30.

The oral test is mandatory, concerns topics of the entire program and is primarily designed to evaluate the ability to apply their knowledge for the proper use of the drugs in clinical practice.

Final vote accounts for 40% of the vote overall written test and 60% vote of the oral test.
Extended program
Drugs acting on the central nervous system
General Anesthetics
Anticonvulsants
Drugs for treatment of neurodegenerative diseases
Pharmacology of drugs of abuse

Endocrine Drugs
Thyroid and Antithyroid
Estrogens, progestins, birth control
Androgens and anabolic steroids
Insulin and oral hypoglycemic

Drugs affecting uterine motility
Chemotherapy
General principles
Antibacterial chemotherapy:
Drugs inhibiting cell wall synthesis
Drugs inhibiting protein synthesis
Fluoroquinolones
Sulfonamides and trimethoprim
Metronidazole
Anti-tuberculosis
Antiprotozoal chemotherapy
Antiviral chemotherapy
Antifungal chemotherapy
Antineoplastic chemotherapy
Obiettivi Agenda 2030 per lo sviluppo sostenibile
5
Condividi su