Animal science
Study-unit Code
In all curricula
Chiara Brachelente
  • Chiara Brachelente
  • 54 ore - Chiara Brachelente
Course Regulation
Coorte 2022
Learning activities
Discipline della sanità animale
Academic discipline
Type of study-unit
Obbligatorio (Required)
Type of learning activities
Attività formativa monodisciplinare
Language of instruction
Principles of general veterinary pathology. Concept of injury and disease, evaluation of morphological, biochemical damage and alteration of homeostasis. Causes of disease, modifications of stationary systems and necrosis. Acute and chronic inflammation. Outcomes of the inflammatory process and wound healing. Immune system disorders. Hepatic, renal and pulmonary pathophysiology.
Reference texts
Patologia generale veterinaria. James F. Zachary. A cura di M. Castagnaro e L. Mechelli L. 4 Edizione. Edra, 2018
Educational objectives
The main objective of the course is to provide the student with the basic knowledge (knowledge) of the main pathological mechanisms of diseases. The main knowledge acquired ("know") will be:
- knowledge of the pathogenetic mechanisms underlying the injury, damage and disease;
- knowledge of functional and morphological alterations associated with stationary system modifications and cellular and extracellular degenerative events
- knowledge of the physiopathological mechanisms of reactive and inflammatory processes and alterations of the immune system
- causes and effects of hepatic, renal and pulmonary metabolic disorders.
The main skills (ie the ability to apply the acquired knowledge) ("knowing how") will be:
- the ability to deduce the ways in which an etiological agent of various nature can produce damage
- the ability to recognize and describe the morphological aspects of a macroscopic lesion in order to interpret its meaning and formulate a morphological diagnosis

Teaching methods
The course is organized as follows:
- Theoretical lessons: classroom lectures related to the course topics
- Practical lessons: the lessons consist of a first introductory part to the explanation of the methods of description of macroscopic lesions and of the formulation of the morphological diagnosis followed by exercises in class on slides or in necroscopic room on cadavers or viscera.
Other information

Learning verification modality
The final exam is carried out with a single final exam. To assess the achievement of the objectives set by the course, an oral test is conducted, conducted by a Commission made up of at least two professors. The methods used to carry out the test are defined and presented to the students on the first day of the lesson. The objectives of the test are to evaluate the ability to recognize and describe the fundamental characteristics of the lesions; the ability to deduce the ways in which an etiological agent can produce damage; c) knowledge of the damage response mechanisms implemented by the cellular and tissue systems of a living organism.
Extended program
"Action of pathogens on animal organisms"
Definition of homeostasis and change in homeostasis. Physical, chemical and biological causes of diseases. Morphological and biochemical lesions.
Predisposing and determinants causes of diseases.

"Cellular adaptations of growth and differentation"
Hyperplasia, hypertrophy, atrophy, hypoplasia, hypotrophy

"Cell death"
Necrosis and apoptosis.

"Acute and chronic inflammation"
Morphologic patterns of acute and inflammation. Outcome of inflammation. Wound healing.

"Disorders of the immune system"
Hypersensitivity. Autoimmunity. Immune deficiency.

"Changes in hepatic function"
Hepatic failure and its correlation with animal production.

"Changes in renal function"
Renal failure and its correlation with animal production.

"Changes in pulmonary function"
Lung failure and its correlation with animal production.
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