Unit INTERGRATED SCIENCES OF HUMAN FUNCTIONS
- Course
- Environment and workplace prevention techniques
- Study-unit Code
- GP003863
- Curriculum
- In all curricula
- CFU
- 6
- Course Regulation
- Coorte 2020
- Offered
- 2020/21
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa integrata
BIOCHEMISTRY
Code | GP003873 |
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CFU | 2 |
Teachers |
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Hours |
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Learning activities | Base |
Area | Scienze biomediche |
Academic discipline | BIO/10 |
Type of study-unit | Obbligatorio (Required) |
Language of instruction | Italian |
Contents | Principle of basic Biochemistry |
Reference texts | Biochimica e Biologia per le professioni sanitarie. McGraw Hill Education |
Educational objectives | Understanding the biochemical mechanism of the cell and the necessary medotology |
Prerequisites | Inorganic and organic chemistry |
Teaching methods | Frontal lessons |
Other information | None |
Learning verification modality | Written exam |
Extended program | Water and biological buffers - amino acids, peptides and proteins - tridimensinal strucure of proteins- protein functions - enzyme and enzyme catalysis - carbohydrates and glycobiology - monosaccharides- disaccharides and polysaccharides - nucleic acid - lipids- storage lipis - structural lipids- biological membranes - membrane transport - biosignaling - bioenergetics and metabolism- glycolisis and gluconeogensis - Krebs cycle - catabolism of fatty acids - aminoacids oxidation and urea cycle - oxidative phosphorilation - biosynthesis of carbohydrates - biosynthesis of aminoacids - hormonal regulation - protein metabolism - |
APPLIED BIOLOGY
Code | GP003871 |
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CFU | 2 |
Teacher | Cinzia Antognelli |
Teachers |
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Hours |
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Learning activities | Base |
Area | Scienze biomediche |
Academic discipline | BIO/13 |
Type of study-unit | Obbligatorio (Required) |
Language of instruction | Italian |
Contents | Prokaryotic and eukaryotic cells. Flow of genetic information within a biological system and its regulation. Cell cycle and its control. Mutations: types and causes. Reproduction of multicellular living organisms: meiosis and gametogenesis. |
Reference texts | R. Roberti, G. Alunni Bistocchi, C. Antognelli, VN Talesa - Biochimica e Biologia per le professioni sanitarie - McGrawHillP. Bonaldo, S. Suga, R. Pierantoni, P. Riva, M.G, Romanelli- Biologia e Genetica - EdiSES |
Educational objectives | The aim of the course is the integrated study of the cell and living organisms, with emphasis on the mechanisms involved in: organelles biogenesis and cellular structures, cell-cell interactions, cell-extracellular matrix interactions, DNA duplication, transmission of the genetic information, gene expression, cell proliferation. The ability to learn, relate and integrate one concept to another will be considered fundamental issues in order to facilitate the understanding of the disciplines provided in the subsequent years of the Degree Course. |
Prerequisites | Basic elements of chemistry |
Teaching methods | Face-to-face |
Other information | Site of the teacher: Nuova sede dei Dipartimenti di Medicina, Edificio B, 4° piano, P.le L Severi 1, Sant'Andrea delle Fratte, Perugia |
Learning verification modality | Written examination |
Extended program | The characteristics of living organisms. Biological macromolecules: proteins, lipids and glucids (general characteristics). Models of cellular organization: prokaryotes and eukaryotes. Viruses: general characteristics. Animal eukaryotic cell. Plasma membrane: structure and functions. The main mechanisms of membrane transport and cellular communication; cytoplasm; ribosomes; rough and smooth endoplasmic reticulum; Golgi apparatus; lysosomes; peroxisomes; mitochondria and the energy problem; cytoskeleton (general characteristics), nucleus and nucleolus. DNA and RNA: structure and function. Organization of chromatin, chromosomes. The eukaryotic gene. Gene expression: transcription, maturation of primary transcripts, genetic code, translation. Regulation of gene expression: general characteristics. Cell cycle: interphase, DNA replication, mitosis. Cell cycle control: check-point and CdK-cyclines. Proto-oncogenes, oncogenes and tumor suppressor. Gene mutations (point mutations, missense, nonsense, neutral mutations), genomic mutations (aneuploidy and polyploidy mutations) and chromosomal mutations (deletion, duplication, inversion, translocation). Human normal and pathological karyotype. Heterochromatinization of the X chromosome. Reproduction of multicellular organisms; meiosis and its biological meaning, gametogenesis (spermatogenesis and oogenesis). |
MEDICAL GENETICS
Code | GP003872 |
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CFU | 2 |
Teacher | Emilio Donti |
Teachers |
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Hours |
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Learning activities | Base |
Area | Scienze biomediche |
Academic discipline | MED/03 |
Type of study-unit | Obbligatorio (Required) |