Unit GENERAL PATHOLOGY AND PATHOPHYSIOLOGY 1
- Course
- Medicine and surgery
- Study-unit Code
- GP001253
- Curriculum
- In all curricula
- CFU
- 8
- Course Regulation
- Coorte 2023
- Offered
- 2024/25
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa integrata
GENERAL PATHOLOGY AND PATHOPHYSIOLOGY - MOD. 1
| Code | GP004709 |
|---|---|
| CFU | 7 |
| Teacher | Stefano Brancorsini |
| Teachers |
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| Hours |
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| Learning activities | Caratterizzante |
| Area | Patologia generale e molecolare, immunopatologia, fisiopatologia generale, microbiologia e parassitologia |
| Academic discipline | MED/04 |
| Type of study-unit | Obbligatorio (Required) |
GENERAL PATHOLOGY AND PATHOPHYSIOLOGY - MOD. 2
| Code | GP004710 |
|---|---|
| CFU | 1 |
| Teacher | Marina Maria Bellet |
| Teachers |
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| Hours |
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| Learning activities | Caratterizzante |
| Area | Patologia generale e molecolare, immunopatologia, fisiopatologia generale, microbiologia e parassitologia |
| Academic discipline | MED/04 |
| Type of study-unit | Obbligatorio (Required) |
| Language of instruction | Italian |
| Contents | Atrophy and cell injury. Regeneration and adaptive cell responses. Aging and senescence. Pathology of blood and altered activity of blood cells. Immune pathologies. |
| Reference texts | - Kumar, Abbas, Aster "Robbins e Cotran: Le basi patologiche delle malattie" Edra, IX edizione - Pontieri, Russo, Frati "Patologia generale e Fisiopatologia Generale" Piccin, V Edizione |
| Educational objectives | This course is for the student the first teaching that allows to understand the intrinsic and extrinsic causes of disease, including the process of senescence and aging of the cells and their mechanisms to adapt to reversible or irreversible injury. The main aim of this teaching is to provide students with the bases needed to address not only the causes of disease, but also the pathological effect on cells and tissues, strengthening knowledge of physiology and molecular and cellular biology needed to understand pathological processes from molecules to human physiological systems. Main knowledge acquired will be: knowledge of the adaptive mechanisms of the cell; theory of senescence and their mechanisms; aging and cellular mechanism of diseases; knowledge of the pathology of blood cells. The main competences will be the definition of the causes of disease in order to acquire the correct clinical approach for their identification, and for the analysis of biomedical information derived from different diagnostic techniques. |
| Prerequisites | In order to be able to understand and succesfully deal with the majority of argument described within the Course, it is necessary to have successfully passed the Physiology exam. Moreover, other topics matter of the module require deep knowledge of Biochemistry, Molecular and Cellular Biology, Anatomy and Histology. Their knowledge represents a mandatory prerequisite for student planning to follow this course with profit. |
| Teaching methods | Face-to-face and seminar lectures with audiovisual material on all subjects of the Course |
| Other information | No additional information |
| Learning verification modality | The exam consists of an oral test as interview of about 20-30 minutes, aiming to ascertain the knowledge level and the understanding capability acquired by the student on issues proposed. The interview is focused on three important arguments (Pathology, Inflammation/Oncology and Phisiopathology) and require theoretical insights and clarification of details by members of the board of examiners. The examination, as a whole, allows to verify both the ability of knowledge and understanding, and the ability to apply the acquired skills and to develop solutions for independent judgement. |
| Extended program | PROGRESSIVE PROCESSES Physiological and pathological hypertrophy and hyperplasia. Atrophy. Regenerative process in labile, stable and perennial cells. liver regeneration. AGING Theories of senescence. Senescence in intermitotic and post-mitotic cells. Aging of the organism, cellular and subcellular. Programmed ageing. Pathology of aging. BLOOD DISORDERS Blood mass alterations. Red blood cells alterations: anemia, polycythemia, hemoglobinopathies. White blood cells and leukocytosis. Platelets and the process of hemostasis and coagulation. Bleeding. Thrombotic and embolic processes, cid. IMMUNOPATHOLOGIES Elements of immunology: innate and acquired immunity. Immunity cells and receptors. Hypersensitivity types I, II, III and IV. Diseases and major histocompatibility system. Autoimmune diseases. Primary and secondary immunodeficiencies. Notes on the mechanisms of acute and chronic transplant rejection. |