Unit PHYSICAL CHEMISTRY
- Course
- Chemistry and technology of drugs
- Study-unit Code
- 65004708
- Location
- PERUGIA
- Curriculum
- In all curricula
- Teacher
- Paola Sassi
- Teachers
-
- Paola Sassi
- Hours
- 64 ore - Paola Sassi
- CFU
- 8
- Course Regulation
- Coorte 2018
- Offered
- 2019/20
- Learning activities
- Affine/integrativa
- Area
- Attività formative affini o integrative
- Academic discipline
- CHIM/02
- Type of study-unit
- Obbligatorio (Required)
- Type of learning activities
- Attività formativa monodisciplinare
- Language of instruction
- Italian
- Contents
- The course points to the study of the matter, its equilibrium state and transformations. The programme is divided into three main parts: chemical thermodynamics; chemical kinetics; atomic and molecular spectroscopy.
- Reference texts
- "Chimica Fisica" di Raymond Chang, Ed. Zanichelli, vol.1 e 2
- Educational objectives
- The oral examination is aimed to test (a) the knowledge of basic concepts of thermodynamics and kinetics, (b) the knowledge of the theory and experiment of molecular spectroscopic techniques; (c) the student’s ability to clearly describe even complex concepts, by using the proper technical-scientific language, (d) the ability to face and solve new problems as requested to a master graduate.
The minimum requirement to pass the exam is to fulfil (a) and (b) points. A maximum seven/30 evaluation is assigned to point (c); a maximum five/30 evaluation is assigned to point (d). To have a maximum cum laude evaluation, the complete mastery of reported arguments and no intervention from the teacher is requested.
For the student that is not passing the exam, a minimum of two week is requested for the new test and no more than two attempt are allowed in one section (one attempt every section if the student failed four times). - Prerequisites
- basic knowledge of General Chemistry and Mathematics
- Teaching methods
- The course develops on frontal lecturing. At the beginning of each lesson a short summary of precedent arguments will be given to introduce the new subjects. All the basic concepts will be applied to the interpretation of natural phenomena or to the solution of demonstrative exercises. Each part of the course (thermodynamics, kinetics, spectroscopy) will end with a short summary of the general concepts to evidence the connections and stimulate the comparison among different experimental approaches.
- Other information
- attendance is recommended
- Learning verification modality
- Referring to the training objectives stated above, the minimum requirement to pass the exam is to fulfil (a) and (b) points. A maximum seven/30 evaluation is assigned to point (c); a maximum five/30 evaluation is assigned to point (d). To have a maximum cum laude evaluation, the complete mastery of reported arguments and no intervention from the teacher is requested.
For the student that is not passing the exam, a minimum of two week is requested for the new test and no more than two attempt are allowed in one section (one attempt every section if the student failed four times). - Extended program
- Chemical thermodynamics
1)System and environment. Extensive and intensive properties. The first law of thermodynamics
2)Enthalpy and thermochemistry.
3)Entropy and second law of thermodynamics
4)Statistical thermodynamics and the third law of thermodynamics
5)Gibbs free energy function. Physical equilibria involving pure substances.
6)The chemical potential and the properties of solutions
7)The colligative properties: the boiling point elevation; freezing point lowering; osmosis and osmotic preassure
8)Real solutions and activity coefficient. Distillation of binary miscible solutions. Immiscible liquids and surface tension
9)Chemical equilibria and equilibrium constants: the effects of temperature, pressure and reagent addition
10)Solutions of electrolytes. The Debye-Huckel theory. The electrolytic conduction.
11)Electrochemical cells: cells and batteries.
Chemical kinetics
1)Measurement of reaction rate. Orders of reaction.
2)The rate constant and the Arrhenius law. Elementary processes and the theory of the transition state.
3)Ionic reactions. Chain reactions. Explosive reactions. Polymerization reactions and oscillating reactions.
4)Heterogeneous catalysis. Homogeneous catalysis: acid and basic catalysis. Enzymatic catalysis. The Michaelis-Menten kinetics. Inibition processes and allosteric modulation.
Atomic and molecular spectroscopy
1)Modern physics and quantum mechanics
2)Atomic spectroscopy
3)Molecular degrees of freedom and molecular spectroscopies
4)Instrumentation for optical spectroscopies
5)Rotational spectroscopy, absorption and diffusion
6)IR and Raman vibrational spectra
7)Absorpion and emission spectra in the UV-Vis region
8)Circular dichroism
9)Nuclear magnetic resonance